MLP Enhanced CO Emission Prediction Model with LWSSA Nature Inspired Optimization.

Environmental degradation due to the rapid increase in CO₂ emissions is a pressing global challenge, necessitating innovative solutions for accurate prediction and policy development. Machine learning (ML) techniques offer a robust approach to modeling complex relationships between various factors influencing emissions. Furthermore, ML models can learn and interpret the significance of each factor's contribution to the rise of CO.

Recent advances in bioactive materials: Future perspectives and opportunities in oral cancer biosensing.

Bioactive materials and biosensing technologies are emerging as pivotal tools in the early detection and management of oral cancer, a disease characterized by high morbidity and mortality rates. Recent advancements in nanotechnology have facilitated the development of innovative biosensors that utilize bioactive materials for non-invasive diagnostics, particularly through salivary analysis. These biosensors, including electrochemical, optical, and molecular types, target specific biomarkers such as DNA, RNA, and proteins associated with oral cancer.

Nebivolol, an FDA-Approved Drug, Has General Antibacterial and Antibiofilm Effects and Increases Tolerance to Ciprofloxacin.

Background: The repurposing of approved drugs for new activities is gaining widespread attention, including drugs that have antibacterial properties. Nevertheless, besides the benefits of repurposing drugs, the discovery of new antibiotic activity in commonly used medicines raises concerns about inducing antibiotic tolerance and resistance due to the stress produced by the drugs. We found that nebivolol, which is used to treat hypertension, also has antibacterial activity.

The Symbiotic Defence: Lung Microbiota and The Local Immune System.

Microbiota defines all microorganisms that are vital for our immunological, hormonal, and metabolic homeostasis by living symbiotically in different parts of our body. On the other hand, the microbiome is a collection of microorganisms that can be detected together. The lungs are constantly exposed to airborne microorganisms found in the upper respiratory tract.

Post-quarantine anxiety and depression levels of COVID-19 positive patients, Northern Cyprus.

Background: The COVID-19 Pandemic, which started to be seen in Northern Cyprus (NC) as of March 2020, has affected the psychological mood of many people in our country as well as all over the world.

Objectives: It was aimed to evaluate the post-illness anxiety and depression levels of people who were diagnosed with COVID-19 positive, completed the quarantine period and then received a negative PCR report.

Methods: Through the questionnaire used in the study carried out between 1-30 April 2021, the sociodemographic characteristics of the participants and their personal experiences about COVID-19 were questioned and they were asked to answer the questions about the hospital anxiety and depression (HAD) scale.

Repurposing metformin as a potential anticancer agent using in silico technique.

Background: The focus on repurposing readily available, well-known drugs for new, creative uses has grown recently. One such medication is metformin, a drug commonly used to manage diabetes, which shows a favorable correlation between its use and lower cancer morbidity and death. Numerous investigations and clinical trials have been conducted to evaluate the possible application of metformin as an anticancer medication in light of this conclusion.

Effect of coffee thermocycling on the color and translucency of milled and 3D printed definitive restoration materials.

Statement Of Problem: Research on the color and translucency properties of 3-dimensionally (3D) printed definitive resins and the effect of coffee thermocycling on these properties is lacking.

Purpose: The purpose of this in vitro study was to investigate the effect of coffee thermocycling on the color and translucency parameters of the milled and 3D printed materials used for definitive restorations.

Material And Methods: Plate-shaped specimens (12×12×1 mm) of 3 milled (IPS e.

Delayed vs. immediate placement of restorative materials over Biodentine and RetroMTA: a micro-shear bond strength study.

Background: The aim of the present study was to investigate the micro-shear bond strength (µSBS) of various restorative materials applied on two different fast-setting calcium silicate-based materials and to evaluate the effect of restoration time on µSBS.

Methods: A total of 180 acrylic blocks with a cavity in the center were randomly divided into 2 main groups according to the capping material to be used (Biodentine or RetroMTA). The specimens were also randomly divided into 3 groups according to the restoration time (3 min, 12 min, 24 h).

Soft tissue simulant materials in X-ray-based imaging in dentomaxillofacial radiology: a scoping review.

Introduction: In in-vitro dental radiographic research, simulation of soft tissue is required to replicate the clinical condition as close as possible. This study aimed to find out which soft tissue simulation material have been studied to use in dentomaxillofacial radiology and showed similarity in radiodensity to the soft tissues of the maxillofacial region.

Methods: In this scoping review, Web of Science, Embase, Scopus, Google scholar and PubMed databases were searched on April 9, 2023, considering the following PICOS: Population: soft tissue simulants, Intervention: X-ray-based imaging, Comparison: -, Outcome: properties of the soft tissue simulants, Study design: in-vitro studies.

Clinical performance of non-carious cervical lesions restored with using self-etch mode of adhesives according to the FDI criteria.

Aim: The purpose of this study was to evaluate the 18-month retrospective study of self-etch adhesive (Prime&Bond One Select) and self-etch mode of universal adhesives (Single Bond Universal, Gluma Bond Universal) applied to non-carious cervical lesions according to the World Dental Federation criteria.

Materials And Methods: Thirty patients without any systemic disease, good oral hygiene, having at least 20 teeth and six non-carious cervical lesions treated using a self-etch mode of adhesives operated between January and March 2017. Accordingly, 335 restorations were evaluated according to the World Dental Federation criteria at 3, 6, 12 and 18 months.

What Is Going on in Indoor Air Quality of a University Hospital in Northern Cyprus?

Background: There are two main purposes of microbial monitoring of the inanimate hospital environment. One of them is to monitor hygiene standards, and the second is to determine the presence of nosocomial pathogens. This study was aimed to investigate the indoor environment of the different departments of a university hospital.

Identification of the Relationship Between DNA Methylation of Circadian Rhythm Genes and Obesity.

In children, teenagers, and young adults, environmental factors and genetic modifications have contributed to the development of obesity. There is a close relationship between obesity and circadian rhythm. To understand the role of CLOCK and BMAL1 in obesity, we analyzed the methylation status of CLOCK and BMAL1 in obese and control subjects.

Computational Insight into the Mechanism of Action of DNA Gyrase Inhibitors; Revealing a New Mechanism.

Background: Discovery of novel antimicrobial agents is in need to deal with antibiotic resistance. Elucidating the mechanism of action for established drugs contributes to this endeavor. DNA gyrase is a therapeutic target used in the design and development of new antibacterial agents.

[Comparative Analyses of IgA Antibody Response of Non-COVID-19 Infected People Over 60 Years Old Following CoronaVac and Pfizer-BioNTech COVID-19 Vaccination].

The formation rate, magnitude, and duration of the antibody-mediated humoral immune response that develops against different viral proteins of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) are considered important in vaccine success. It is known that the response to vaccinations decreases due to immunosenescence in older adults. This study was aimed to investigate the levels of serum IgA response at 1st and 3rd month after vaccination of people over 60 years old who were immunized with CoronaVac and Pfizer-BioNTech.

Self-reported bio-psycho-social factors partially distinguish patellar tendinopathy from other knee problems and explain patellar tendinopathy severity in jumping athletes: A case-control study.

Objective: To determine what combinations of self-reported factors distinguish patellar tendinopathy (PT) from other knee problems, and explain PT severity variance.

Design: Case-control study.

Setting: Social media, private practice and National Health Service.

Comparative humoral response of mRNA and inactivated vaccines against COVID-19 in healthy adults aged 60 years and older.

Introduction: A vaccine against coronavirus disease 2019 (COVID-19) is critically needed for older adults because of the increased morbidity and mortality rates.

Methodology: In this prospective study, we analysed the titre magnitude of the IgG antibodies directed against the SARS-CoV-2 Spike Protein S1 (S1-RBD) antigen in both CoronaVac and Pfizer-BioNTech groups. The samples were tested to detect antibodies that bind to the receptor-binding domain of the spike protein of SARS-CoV-2 using the Enzyme-Linked Immunosorbent Assay (ELISA) technique with SARS-CoV-2 IgG II Quant.

Impact of different intraorifice barriers on fracture resistance of non-vital bleached teeth.

Background And Aim: This study aimed to evaluate the effects of bleaching agents on the fracture resistance of endodontically treated teeth using different intraorifice barrier (IOB) materials.

Materials And Methods: The endodontic treatment was performed for 160 mandibular premolars, and then, the teeth were divided into four groups according to the IOB: Ionoseal, Biodentine, ProRoot MTA, and TheraBase. Then, these teeth were subdivided into four subgroups (n = 10) based on the bleaching agents as distilled water (control), hydrogen peroxide 35% (HP), sodium perborate (SP), and carbamide peroxide 37% (CP).

Cancer Stem Cells and Their Therapeutic Usage.

Cancer stem cells (CSC) have unique characteristics which include self-renewal, multi-directional differentiation capacity, quiescence/dormancy, and tumor-forming capability. These characteristics are referred to as the "stemness" properties. Tumor microenvironment contributes to CSC survival, function, and remaining them in an undifferentiated state.

Shade matching potential of one-shade resin composites used for restoration repair.

To evaluate shade matching ability of one-shade composites used for repair of different resin-based restorative materials. Two one-shade composites or one layering composite of 1 mm thickness were placed over non-aged or aged 3 different base materials of 1 mm thickness to simulate repair. Two millimeters thick base samples were prepared and used for reference (n=12).

Investigation of Brucella canis and Brucella abortus Seropositivity by In-House Rapid Slide Agglutination Test and In-House ELISA in Northern Cyprus.

The incidence of Brucella canis (B. canis) in humans is unknown in Northern Cyprus. In this study, we investigated the prevalence of B.

Epigenetic Alteration in Colorectal Cancer: A Biomarker for Diagnostic and Therapeutic Application.

Colorectal cancer (CRC) is the leading cause of cancer death worldwide. A crucial process that initiates and progresses CRC is various epigenetic and genetic changes occurring in colon epithelial cells. Recently, huge progress has been made to understand cancer epigenetics, especially regarding DNA methylation changes, histone modifications, dysregulation of miRNAs and noncoding RNAs.

Self-reported bio-psycho-social factors partially distinguish rotator cuff tendinopathy from other shoulder problems and explain shoulder severity: A case-control study.

Objective: Examine how rotator cuff (RC) tendinopathy differed from other shoulder problems (OSP) by measuring a variety of self-reported bio-psycho-social factors, and establish which explain severity.

Methods: A validated online survey battery was used to collect self-reported biopsychosocial variables in an international population. Diagnostic group and severity were the dependent variables.

Comparison of the Efficacy of the Panoramic and Cone Beam Computed Tomography Imaging Methods in the Surgical Planning of the Maxillary All-On-4, M-4, and V-4.

This study is aimed at analyzing the difference between the measurements made according to certain anatomical signs of the maxillary jaw using panoramic radiography and cone beam computed tomography (CBCT) to decide whether to use all-on-4, M-4, or V-4 configuration to prevent complications caused by incorrect measurements during the presurgical planning stage of the placement of implants in the all-on-4 technique. A retrospective study was conducted with 50 patients with upper edentulous jaws suitable for the all-on-4 technique, who underwent preoperative panoramic radiography and cone beam computed tomography evaluation for dental implant surgery. The shortest vertical distances between anatomical structures were measured.