315 results match your criteria: "Cutis Verticis Gyrata"

Cutis verticis gyrata (CVG) is a rare benign neurocutaneous condition marked by thickened scalp folds resembling cerebral gyri and sulci. It has been classified into primary essential, primary non-essential, and secondary types. The primary essential type is idiopathic, and the primary non-essential type may be associated with neurological or ophthalmological complications.

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Article Synopsis
  • Cutis Verticis Gyrata (CVG) is a rare skin condition that can occur on its own or as a result of other diseases, with notable complexities in diagnosing it alongside genetic syndromes like Noonan and Turner syndromes.
  • A case study of a 38-year-old patient with CVG and a history of these syndromes highlighted the diagnostic challenges and the importance of using advanced imaging and histology for confirmation.
  • The report emphasizes the need for healthcare providers to consider rare conditions like CVG in their differential diagnoses to ensure timely and accurate treatment, thereby improving patient outcomes by addressing any associated genetic and systemic issues.
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  • - A 17-year-old patient was diagnosed with pachydermoperiostosis, a rare genetic condition that causes painful joint swelling and distinct facial features, after being referred to rheumatology.
  • - Genetic testing revealed a specific variant (SLCO2A1) linked to more severe symptoms, including significant functional impairment and psychosocial issues due to the patient's appearance.
  • - The condition is multi-systemic and can lead to serious complications like myelofibrosis and gastric issues, emphasizing the need for early detection and further research in medical management options.
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Cutis verticis gyrata in a patient with acromegaly: an unusual case and review of literature.

Dermatol Online J

June 2024

Laboratory of Epidemiology, Clinical Research and Public Health, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, University of Mohammed 1st, Oujda, Morocco.

Article Synopsis
  • * Cutis verticis gyrate (CVG) is a rare skin complication seen in some acromegaly patients, characterized by the abnormal growth of scalp skin resulting in folds and furrows.
  • * Treatment involves managing growth hormone and IGF1 levels through surgery or injections, and the diagnosis of CVG is primarily clinical, requiring no imaging.
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Acromegaly in humans and cats: Pathophysiological, clinical and management resemblances and differences.

Growth Horm IGF Res

June 2024

Pituitary Tumor Unit, Endocrinology Department, Hospital CUF Descobertas, Lisbon, Portugal; Faculdade de Medicina, Universidade Católica Portuguesa, Lisbon, Portugal. Electronic address:

Article Synopsis
  • Acromegaly is a disorder caused by excess growth hormone (GH) and insulin-like growth factor-1 (IGF-1), leading to distinct physical changes and various health complications in both humans and cats.
  • A literature review highlighted similarities and differences in how acromegaly manifests in these species, including craniofacial changes, joint issues, and cardiometabolic risks.
  • Both species experience growth-related problems and associated diseases, but unique symptoms like human-specific skin conditions and different physical changes in cats distinguish their presentations.
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  • Cutis verticis gyrata (CVG) is a rare skin condition featuring ridges and furrows on the scalp, categorized into primary essential, primary nonessential, and secondary types.
  • The case focuses on primary essential CVG, where a significant portion of the scalp and forehead was affected, requiring flap advancement after skin expansion for treatment.
  • This successful technique not only covers the skin defect and preserves hair growth but also leads to excellent cosmetic results, enhancing both the appearance and psychosocial well-being of the patient.
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Article Synopsis
  • Cutis verticis gyrata (CVG) is a rare benign scalp disorder characterized by deep folds and furrows that resemble brain structures.
  • The case reported involves a 3-week-old girl with primary CVG and an echocardiographic diagnosis of cor triatriatum, a type of congenital heart defect.
  • The findings suggest that while CVG is usually linked with neuropsychiatric and ophthalmologic issues, it may also be associated with isolated congenital heart defects, warranting careful evaluation in affected patients.
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Bulldog Scalp Syndrome.

Indian J Plast Surg

December 2023

Department of Burns and Plastic Surgery, All India Institute of Medical Sciences, Bathinda, Punjab, India.

Article Synopsis
  • Bulldog scalp syndrome, or cutis verticis gyrata (CVG), is a rare skin disorder characterized by scalp thickening that resembles bulldog skin folds, occurring in 0.026 to 1 per 100,000 people, and can significantly impact patients' social and psychological well-being.
  • It can be divided into primary (essential or nonessential) and secondary types, with symptoms varying in severity, and cosmetic concerns being the primary issue.
  • Surgical intervention is the best treatment to enhance appearance, and while both cases had different causes, they were successfully managed through the removal of skin folds, leading to patient satisfaction and a positive prognosis with no signs of malignant transformation.
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Article Synopsis
  • Cutis verticis gyrata (CVG) is a benign scalp condition characterized by convoluted folds and deep furrows that can resemble brain structures, causing concern for patients and their families.
  • Diagnosing CVG can be challenging, as it may be mistaken for other skin conditions, and the ultrasonic pattern had not been previously documented.
  • A study of 14 patients revealed specific ultrasound findings, such as thickened dermal and hypodermal layers and undulating cutaneous layers, which can aid in diagnosing CVG and distinguishing it from other scalp dermatological issues.
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Congenital Cutis Verticis Gyrata in a Newborn with Turner Syndrome: A Rare Clinical Manifestation of This Chromosomal Disease with Trichoscopic Evaluation.

Diagnostics (Basel)

August 2023

Section of Dermatology and Venereology, Department of Precision and Regenerative Medicine and Ionian Area (DiMePRe-J), University of Bari "Aldo Moro", 70124 Bari, Italy.

Article Synopsis
  • Cutis verticis gyrata (CVG) is a rare scalp disorder characterized by ridges and furrows that resemble brain anatomy, classified into primary essential, primary non-essential, and secondary forms based on associated conditions.
  • A case report of a one-month-old female with congenital CVG (CCVG) and Turner syndrome highlights the condition's skin folding at birth in the left frontal scalp area.
  • The study emphasizes the importance of clinical and trichoscopic diagnosis for CVG, potentially linking it to various genetic, inflammatory, and neoplastic conditions, and suggests that non-invasive techniques like brain and scalp ultrasonography can aid in classification.
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Autologous fat grafting as a novel technique for primary essential cutis verticis gyrata.

JPRAS Open

September 2023

Burn Unit and Plastic and Reconstructive Surgery Department, Fundación Santa Fé de Bogotá, Bogotá, Colombia.

Article Synopsis
  • The text discusses various treatment options for CVG, highlighting that surgery is typically favored, but recent methods may not always be ideal.
  • It presents a case study of a 51-year-old Colombian man who received autologous fat injections on his scalp after no success with previous treatments.
  • The results showed significant cosmetic improvements with this less invasive method, which could still allow for future surgical options if needed.
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[Folliculitis decalvans on a cutis verticis gyrata].

Rev Prat

May 2023

Département de dermatologie, université Mohammed-VI, hôpital d'Oujda, Maroc. Laboratoire d'épidémiologie, recherche clinique et santé publique, faculté de médecine et de pharmacie, université Mohammed-VI, hôpital d'Oujda, Maroc.

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Article Synopsis
  • Two cases of congenital hairline deformity were presented, characterized by wrinkled skin and ulcerated lesions due to hair irritation in the occipital region.
  • Both patients exhibited a unique pattern of raised wrinkles and a defect in the frontotemporal hairline on one side, without any other health issues.
  • Treatment involved excising excess skin and transplanting follicular units to restore the hairline, which resulted in natural-looking hair growth without any specific abnormalities detected.
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Article Synopsis
  • A 68 Ga-PSMA PET/CT scan was performed on a prostate cancer patient, showing increased PSMA uptake in an uncommon scalp condition called cutis verticis gyrata (CVG).
  • CVG causes the scalp to thicken and develop deep grooves, resembling features of the cerebral cortex.
  • The case highlights that 68 Ga-PSMA uptake can also occur in noncancerous conditions, supporting existing research on benign illnesses.
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