13 results match your criteria: "Cutaneous Melanoacanthoma"
Melanoacanthoma: a potential pitfall of reflectance confocal microscopy.
An Bras Dermatol
January 2020
Cutaneous Oncology Department, AC Camargo Cancer Center, São Paulo, SP, Brazil.
Article Synopsis
- Melanoacanthoma is a rare skin condition similar to seborrheic keratosis, marked by dark pigmentation and rapid growth, which complicates its differentiation from melanoma.
- *The condition is defined by a mixture of keratinocytes and dendritic melanocytes, which are cells that produce pigment.
- *In a case study, a fast-growing scalp lesion was examined and ultimately excised because it could not be reliably classified as benign; further analysis confirmed it as melanoacanthoma.
Clinical and Dermoscopic Features of Cutaneous Melanoacanthoma.
JAMA Dermatol
October 2015
Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Anogenital giant seborrheic keratosis.
G Ital Dermatol Venereol
August 2017
Georg Schmorl Institute of Pathology, Dresden-Friedrichstadt Academic Teaching Hospital, Dresden, Germany.
Article Synopsis
- Seborrheic keratosis (SK) is a common benign skin tumor, while giant seborrheic keratosis (GSK) is a rare variant that can be misdiagnosed, especially in genital areas where it is unusual.
- The potential causes of GSK may include chronic friction and HPV infection, making it crucial to differentiate it from similar conditions like Buschke-Löwenstein tumor and melanoma.
- Accurate diagnosis often requires histological verification since GSK's typical features can be lacking in genital lesions, and surgical treatment is the preferred approach, as demonstrated in a case involving a 72-year-old patient with GSK and HPV.
Multifocal cutaneous melanoacanthoma with ulceration: a case report with review of literature.
Indian J Dermatol Venereol Leprol
February 2012
Department of Dermatology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India.
Article Synopsis
- - A 58-year-old woman had multiple raised pigmented lesions on her body for 10 years, with one lesion ulcerating over the last five months.
- - Histopathological examination confirmed the presence of melanoacanthoma in the ulcerated lesion.
- - This case is notable as the first report of cutaneous melanoacanthoma presenting with an ulcerated plaque and only the third case with multiple lesions, a previously unreported feature in medical literature.
A Case of Melanoacanthoma: Immunohistochemical Staining Using VECTOR® NovaRED™ to Distinguish Melanocytes from the Cutaneous Pigment.
Ann Dermatol
March 2008
Department of Dermatology, College of Medicine, Korea University, Seoul, Korea.
Article Synopsis
- Melanoacanthoma is a rare, benign tumor that involves both keratinocytes and melanocytes, distinguishing it from the related condition seborrheic keratosis.
- * It features large melanocytes filled with melanin and shows issues in transferring melanin to surrounding skin cells.
- * The study introduces a unique staining method (VECTOR® NovaRED™) that helps differentiate between melanocytes and melanin-laden keratinocytes for better diagnosis.*
Oral melanoacanthoma and oral melanotic macule: a report of 8 cases, review of the literature, and immunohistochemical analysis.
Med Oral Patol Oral Cir Bucal
September 2007
Departamento de Patología y Medicina Oral, Centro Clínico de Cabeza y Cuello, Guatemala.
Article Synopsis
- Oral melanoacanthoma (MA) is a rare, benign pigmented lesion in the mouth, with its cause still unclear but likely related to a reactive process, typically found in younger black females.
- Oral melanotic macule (MM), another pigmented lesion, appears as a small brown-to-black spot, primarily affecting middle-aged females, and its cause is also uncertain.
- A biopsy is important to differentiate between MA, MM, and other similar oral lesions, as demonstrated by four case studies of these conditions in Caucasian and Latin American mestizo patients, including a unique case of MA in a Caucasian boy.
Oral melanoacanthosis (melanoachantoma): report of a case and review of the literature.
Med Oral Patol Oral Cir Bucal
May 2005
Centro de Medicina Oral de Guatemala, Ciudad de Guatemala, Guatemala.
Article Synopsis
- Oral melanoacanthosis (MA) is a rare pigmented lesion in the mouth, similar to cutaneous melanoacanthoma.
- It typically affects black females and commonly appears in areas like the buccal mucosa, lip, palate, and gingiva.
- Diagnosis requires a biopsy due to its non-specific appearance, as it needs to be distinguished from other melanocytic lesions, including melanoma.
Giant cutaneous melanoacanthoma.
Int J Dermatol
December 2004
Department of Dermatology, New Jersey Medical School, Newark, New Jersey 07103-2714, USA.
Oral melanoacanthoma: a report of 10 cases, review of the literature, and immunohistochemical analysis for HMB-45 reactivity.
Am J Dermatopathol
February 2003
Department of Oral and Maxillofacial Pathology, Medicine and Surgery, Temple University School of Dentistry, Philadelphia, Pennsylvania 19140-5096, USA.
Article Synopsis
- - Oral melanoacanthoma (MA) is a rare lesion in the mouth characterized by the overgrowth of certain skin cells, similar to its skin counterpart, but it does not relate to seborrheic keratosis.
- - This study adds 10 new cases to the existing literature, confirming that oral MA commonly appears as a flat or slightly raised dark area on the buccal mucosa, mainly in adult black women, but across a broader age range than previously noted (5-77 years).
- - All cases showed strong reactivity to HMB-45, suggesting this marker is not effective for differentiating oral MA from malignant melanoma.
Melanoacanthosis (melanoacanthoma) of the oral mucosa.
J Dermatol Surg Oncol
March 1990
Department of Oral Pathology, Indiana University School of Dentistry, Indianapolis.
Article Synopsis
- The text discusses a type of pigmented lesion found in the mouth that looks similar to a skin condition called melanoacanthoma.
- A study of 22 cases reveals that this lesion typically occurs in adult black women, particularly on the cheeks (buccal mucosa) and lips.
- The lesion is known to regress over time, and the authors propose using the term "melanoacanthosis" to describe it.
Article Synopsis
- The labial melanotic macule features more dendritic melanocytes in the basal layer and has similar counterparts on other mucosal and skin surfaces.
- Melanoacanthoma, while having a comparable number of melanocytes at the junctional zone, differs by showing dendritic melanocytes within the epithelium and can be found in other oral areas.
- All mucosal melanoses should be carefully evaluated as they may not be distinguishable from malignant melanoma through visual inspection alone, making biopsy essential for accurate diagnosis.
Melanotic macules and melanoacanthomas of the lip. A comparative study with census of the basal melanocyte population.
Am J Dermatopathol
October 1987
Department of Pathology, Milton S. Hershey Medical Center, Hershey, Pennsylvania.
Article Synopsis
- A study analyzed 15 labial melanotic macules and 3 melanoacanthomas on the lip, focusing on their unique histopathological characteristics and the basal melanocyte population.
- Both conditions exhibited increased melanocytes along the junctional zone, but melanoacanthomas had extra intraepithelial melanocytes, differentiating them from melanotic macules.
- The research suggests that the labial melanotic macule shares many histological similarities with other skin and mucosal conditions, indicating broader analogies within oral tissues.