2,209 results match your criteria: "Cutaneous Larva Migrans"

An 8-year-old boy developed serpiginous erythema on the soles of his feet and was diagnosed with cutaneous larva migrans (CLM). Following treatment with ivermectin, the erythema improved within 7 days, but it recurred 14 days later, requiring a second dose for complete resolution. Ultrasound and MRI did not reveal any parasites, but fluctuations in eosinophils, IgE and IgA levels were observed during treatment.

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Article Synopsis
  • The study focuses on the prevalence and risk factors of zoonotic intestinal helminth infections in cats across Indonesia's five major cities (Jabodetabek).
  • Fecal samples from both shelter and household cats showed a significant infection rate (37.9%) with various types of helminths, indicating serious public health concerns.
  • The research highlights the need for improved management practices, such as regular deworming and better hygiene, to prevent the spread of these infections to humans and other animals.
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Travel- and migration-associated epidermal parasitic skin diseases. A review.

Travel Med Infect Dis

October 2023

Institute of Microbiology, Infectious Diseases and Immunology, Charité University Medicine Berlin, Freie Universtät Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany. Electronic address:

Epidermal parasitic skin diseases are a family of parasitic diseases which occur globally or are frequent in special settings. Epidermal parasitic skin diseases occur in travelers and migrants, although epidemiology and/or clinical manifestations differ between these groups. The objective of this study is to summarize the existing knowledge concerning tungiasis, hookworm-related cutaneous larva migrans, scabies, pediculosis capitis and pediculosis corporis in the context of travel and migration, and to identify risk factors for infection.

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Approach to skin problems in travellers: clinical and epidemiological clues.

J Travel Med

December 2024

Infectious and Tropical Diseases, Sorbonne University, Faculté de médecine, Hôpitaux Universitaires Pitié Salpêtrière, Boulevard de l'Hôpital, 75013, Paris, France.

Article Synopsis
  • Travelers often experience skin problems requiring medical attention, with proper diagnosis relying on clinical examinations and understanding travel history and behaviors.* -
  • The most common travel-related skin issues include insect bites, sunburns, and infections like hookworm and bacteria, with specific diseases like dengue fever and schistosomiasis being noteworthy.* -
  • Evaluating skin conditions involves considering travel history, activities, and specific lesion characteristics, which help identify risks and guide treatment.*
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Locally acquired cutaneous larva migrans in Ontario?

Travel Med Infect Dis

September 2024

Department of Medicine, University of Toronto, Toronto, ON, Canada; Division of Infectious Diseases, University of Toronto, Toronto, ON, Canada. Electronic address:

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Article Synopsis
  • Cutaneous larva migrans (CLM), also known as creeping eruption, is an infection caused by hookworms that affects the skin, particularly on the lower legs.
  • *It presents with unique red, winding lesions that appear elevated, primarily diagnosed through clinical observation.
  • *Treatment often includes topical and oral medications like ivermectin, albendazole, and thiabendazole cream.
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Article Synopsis
  • Cutaneous larva migrans (CLM) is an ectoparasitic infection mainly caused by nematodes like Ancylostoma braziliense and Ancylostoma caninum, typically found in tropical and subtropical regions.
  • This study presents two cases of CLM that showcased rare follicular involvement in patients who developed skin lesions after traveling to subtropical areas, with one patient returning from Thailand and the other from Senegal.
  • Histological analysis revealed nematode larvae moving through hair follicles, and skin ultrasound was used to help visualize the parasites, highlighting the importance of recognizing follicular involvement in diagnosing and understanding CLM.
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Article Synopsis
  • Cutaneous larva migrans (CLM) is a skin condition caused by hookworm larvae from contaminated soil, leading to itchy, wavy tracks on the skin.
  • Two patients, a 42-year-old man and a 38-year-old man, treated with a combination of albendazole and ivermectin saw their symptoms resolve completely within a week.
  • The study emphasizes the effectiveness of this treatment approach for CLM and suggests further research is needed due to potential resistance to other antihelminthic therapies.
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Article Synopsis
  • A female patient experienced itching and painful lesions in her mouth for 7 months, with symptoms including swelling and serpentine tracks on her buccal and lip mucosa.
  • She was diagnosed with oral larva migrans, a parasitic infection, which resolved after treatment with ivermectin.
  • At an 18-month follow-up, there were no signs of recurrence, highlighting the importance for oral health providers to consider this condition when diagnosing similar oral lesions.
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Fatal Hymenolepis nana-associated visceral larva migrans in captive juvenile white-tailed antsangies (Brachytarsomysalbicauda).

J Comp Pathol

July 2024

International Zoo Veterinary Group, Station House, Parkwood Street, Keighley BD21 4NQ, UK. Electronic address:

Article Synopsis
  • White-tailed antsangies, a type of Madagascan rodent, were found to have an outbreak of H. nana, a type of tapeworm, marking the first recorded case in this species.
  • The examination of the affected rodents revealed cysticerci (larval form of the tapeworm) in multiple organs, including the intestines and liver, and identified gross lesions through histopathological methods.
  • DNA testing confirmed the presence of H. nana in all cases, suggesting that these infections may lead to unique pathological features like visceral larva migrans in white-tailed antsangies, different from typical rodent hosts.
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Article Synopsis
  • Toxocariasis is a zoonotic infection from dog and cat larvae that can pose serious health risks to humans, with a case described involving a 21-year-old male who had close contact with a pet dog.
  • The patient's symptoms initially resembled a common liver abscess, with lab results showing elevated white blood cells and IgE levels, but persistent fever led to more testing revealing a Toxocara-induced liver abscess.
  • Successful treatment with albendazole demonstrated significant improvement, highlighting the importance of considering toxocariasis in liver abscess cases, especially in regions with high rates of infection, and the need for thorough diagnostic methods beyond serological tests.
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Article Synopsis
  • Toxocariasis is a zoonotic infection caused by parasitic roundworms from dogs and cats that can lead to various health issues in humans, primarily mild febrile illness, but also severe cases affecting eyes and internal organs.
  • Research shows that the disease results in an estimated loss of 91,714 Disability-Adjusted Life Years (DALYs) annually worldwide, with a significant portion associated with cognitive impairment in children.
  • The study highlights a link between pet prevalence and human infection rates, indicates a substantial economic impact of around $2.5 billion annually, and calls for more research and targeted interventions to address this health concern.
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Alterations of plasma circulating microRNAs in BALB/c mice with Toxocara canis visceral and cerebral larva migrans.

Parasit Vectors

June 2024

College of Animal Sciences, Zhejiang Provincial Key Laboratory of Preventive Veterinary Medicine, Zhejiang University, Hangzhou, China.

Article Synopsis
  • Human toxocariasis, caused by Toxocara roundworms from pets, affects 1.4 billion people and leads to serious health issues in humans, including visceral and cerebral larva migrans.
  • The study involved sequencing small RNAs to identify specific microRNAs (miRNAs) in the larvae and infected mice, finding significant changes in miRNA levels that correlate with the disease's progression in the mice.
  • Two particular murine miRNAs (miR-26b-5p and miR-122-5p) were identified as potential biomarkers for diagnosing toxocariasis, providing insights into the host-parasite interactions.*
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Organ-specific Toxocara canis larvae migration and host immune response in experimentally infected mice.

Parasites Hosts Dis

May 2024

Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam 13620, Korea.

Article Synopsis
  • The study focused on how Toxocara canis larvae migrate to specific organs in infected mice, examining the immune response over time.* -
  • Mice were infected with 1,000 larvae and analyzed at 1, 3, and 5 weeks post-infection, revealing changes in parasite load, especially in the liver and lungs, with some larvae remaining in the brain and eyes without significant inflammation.* -
  • The research highlighted increases in certain immune cells and cytokines, suggesting an anti-inflammatory response while providing insights that could enhance understanding of toxocariasis in humans.*
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Vesiculobullous Cutaneous Larva Migrans in the Absence of Domestic Dogs and Cats. Successful Treatment with Oral Ivermectin.

Trop Med Infect Dis

May 2024

One Health Research Group, Facultad de Medicina, Universidad de las Américas, P.O. Box 17-17-9788, Quito 170513, Ecuador.

Article Synopsis
  • * The infection is believed to have come from wild animals carrying larvae, highlighting the risks of working in such environments.
  • * She was successfully treated with oral ivermectin 31 days post-infection, emphasizing the importance of detailed travel history for accurate diagnosis and treatment.
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Understanding the research and practical needs required to control toxocariasis in Iran.

Parasite Epidemiol Control

May 2024

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Article Synopsis
  • Human toxocariasis (HT) is a significant zoonotic infection, especially in tropical regions, and understanding it better is essential for addressing its socioeconomic impact and control measures.
  • A comprehensive review of available research and documents in Iran revealed critical gaps in knowledge, particularly regarding worm burdens, reinfection rates in definitive hosts, and detection methods for the parasite.
  • Effective prevention and control strategies should focus on assessing environmental egg density, identifying at-risk populations, improving early diagnosis techniques, and enhancing public health education about the infection.
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Article Synopsis
  • * Diagnosis is typically made through visual symptoms, but Point of Care Ultrasound (POCUS) can help confirm cases by identifying structures in the skin.
  • * In a reported case, an 18-year-old woman developed itchy feet after walking on the beach, and POCUS confirmed larva migrans, allowing for effective treatment with medication.
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Article Synopsis
  • Cutaneous Larva Migrans (CLM) is a common skin condition caused by hookworms, mostly found in subtropical and tropical areas.
  • A case of a 32-year-old man who developed a severe rash while in Thailand was misdiagnosed at first but was later successfully treated for CLM after receiving anthelminthic therapy.
  • Highlighting atypical presentations of CLM is important for healthcare providers to ensure timely diagnosis and to minimize patient stress.
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Anthelmintic activity and chemical profile of native plant extracts from the Yucatan Peninsula against Toxocara canis.

Acta Trop

July 2024

Fundación MEDINA, Avenida del conocimiento, 34 Parque Tecnológico de Ciencias de la Salud, Granada 18016, España.

Article Synopsis
  • Toxocara canis causes health issues in humans and puppies, with the main treatment typically being anthelmintics, though there's growing resistance to these drugs.
  • The study explored the anthelmintic properties of ethanolic, methanolic, and aqueous extracts from five native plants in the Yucatan Peninsula against T. canis eggs.
  • Results showed that extracts from Alseis yucatanensis and Macrocepis diademata significantly inhibited larval development, and the chemical profiling of A. yucatanensis revealed several active compounds, indicating potential for these plants as natural treatments.
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Article Synopsis
  • Cutaneous larva migrans (CLM) is a skin infection caused by hookworm larvae, typically found in tropical regions, and is characterized by itchy, snake-like rashes.
  • A case study details a 27-year-old woman who developed a serpiginous lesion on her foot after possible exposure to contaminated soil.
  • The patient was effectively treated with Albendazole, and clinicians should be alert to this condition in patients who have traveled to tropical areas, particularly those who walk barefoot.
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