6,366 results match your criteria: "Cukurova University; Adana-Turkey. onur_akpinar@yahoo.com.[Affiliation]"

Objective: It is known that protozoa and helminths that cause intestinal infections adversely affect human life. Changing climate and demographic and socio-economic factors worldwide necessitate the determination and updating of the incidence of these parasites. Our study aimed to retrospectively examine the distribution of intestinal parasites detected in the Parasitology Laboratory of Çukurova University Faculty of Medicine between 2017 and 2021.

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  • Phenylketonuria (PKU) is a genetic condition where too much phenylalanine (Phe) builds up in the body, which can be harmful to the brain.
  • The APHENITY study tested a new medicine called synthetic sepiapterin to see if it could safely lower Phe levels in patients with PKU.
  • The study involved 187 participants from 34 locations around the world and lasted from September 2021 to April 2023, with results showing how effective the treatment was over a six-week period.
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The wide-ranging use of heavy metals and pesticides worldwide and their irreversible accumulation in aquatic ecosystems is a major concern. As the range of household and agricultural chemicals increases, water pollution is trending from the toxic effects of a single agent to complex agent pollution that threatens aquatic ecosystems. The aim of this study was to investigate the effects of pesticides (imidacloprid, IMI) and metals (copper sulfate, CuSO) on oxidative stress biomarkers, antioxidant enzymes, and biomolecular parameters.

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  • The Mediterranean Sea is really polluted, especially with tiny pieces of plastic called microplastics.
  • Researchers have looked at many studies about this pollution over the past few years, focusing mostly on fish and other sea animals.
  • There are still big gaps in our understanding, especially in the southern parts of the Mediterranean and the Black Sea, so more studies need to be done in a more organized way.
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  • The study aimed to evaluate factors impacting cancer-specific survival (CSS) in muscle-invasive bladder cancer (MIBC) patients who did not respond to neoadjuvant chemotherapy (NAC) before undergoing radical cystectomy (RC).
  • Researchers examined various clinical and pathological characteristics, comparing NAC-responsive and NAC-non-responsive patients, focusing on data from 92 male-dominant participants averaging 61.5 years in age.
  • Results indicated that while factors like a higher ECOG score and fewer NAC cycles correlated with non-responsiveness, the only significant prognostic factor for CSS in non-responsive patients was the presence of ypN+ status.
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Prosthesis applications and challenges in children with earthquake-related amputations.

Injury

November 2024

Cukurova University, Faculty of Medicine, Department of Orthopaedics and Traumatology, Adana, Türkiye. Electronic address:

Article Synopsis
  • - The study focuses on children who suffered limb loss due to the 2023 Kahramanmaraş earthquake, examining their injuries, stump issues, and experiences with prosthesis applications and complications.
  • - A total of 102 patients, mostly aged around 13, underwent 120 amputations, primarily involving lower extremities, with a significant number requiring revision surgeries and socket adjustments for prosthetics.
  • - The research highlights challenges in providing proper care for pediatric amputees, including limited resources, emergency surgery conditions, and the need for ongoing support, aiming to improve care strategies for similar future disasters.
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LETter To the EditoR Standards (LETTERS): Considerations for Authors, Reviewers, and Editors.

J Korean Med Sci

September 2024

Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK.

Correspondence in the form of letters to the editor serves multiple scholarly purposes, including critiquing previously published articles, engaging in discourse with other correspondents, commenting on the journal's structure or style, and contributing insights for future publications. The composition of such letters warrants meticulous attention, as they play a crucial role in fostering communication between the journal and its readership. Adherence to specific principles is essential in crafting an effective letter to the editor.

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Background: We evaluated the efficacy of different immunosuppressive regimens in patients with primary membranous nephropathy in a large national cohort.

Methods: In this registry study, 558 patients from 47 centers who were treated with at least one immunosuppressive agent and had adequate follow-up data were included. Primary outcome was defined as complete (CR) or partial remission (PR).

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Purpose: Klebsiella pneumoniae is a significant cause of healthcare-associated infections, resulting in high morbidity and mortality rates due to limited treatment options. In this study, we aimed to evaluate the treatment outcomes and the safety of Ceftazidime-avibactam in infections caused by extensively drug-resistant or pandrug-resistant Klebsiella pneumoniae in pediatric patients.

Methods: This study included pediatric patients who received ceftazidime-avibactam treatment due to extensively drug-resistant or pandrug-resistant Klebsiella pneumoniae infections, monitored in the pediatric intensive care, neonatal intensive care, and pediatric wards of Cukurova University Faculty of Medicine between 2022 and 2023.

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We investigated the hypoglycemic activity and pharmacokinetic study of two synthesized benzoyl benzodioxol derivatives, compound I (methyl 2-(6-(2-bromobenzoyl)benzo[][1,3]dioxol-5-yl)acetate), and compound II, 2-(6-benzoylbenzo[][1,3]dioxol-5-yl)acetic acid, which showed very strong α-amylase inhibiting activity in our previous study. Then, diabetes was induced by the injection of streptozotocin to mice. The molecular docking simulations and analyses of density functional theory analyses were conducted to study the binding interactions with human pancreatic alpha-amylase, and their pharmacokinetic properties were further evaluated by ADMET profiling.

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Background: Tennis requires movement abilities in changing playing situations. This article investigates the relationship between lower extremity strength asymmetry ratio and linear and multidimensional running performances in female tennis players.

Methods: A total of 56 female tennis players, with a mean age of 15.

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We assessed, with validated instruments, whether family atmosphere, religiosity or lifestyle were significant correlates of self-esteem and/or self-control among adolescents (Grades 7-12, n = 2067) in Saudi Arabia. Participants' mean age was 15.5 years; 64% were boys.

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  • Phenylketonuria (PKU) is a common disorder requiring a strict Phe-restricted diet for patients, especially when blood phenylalanine levels exceed 6 mg/dL.
  • A study with 105 PKU patients explored exposure to bisphenols and phthalates, finding that those with fewer dietary restrictions had significantly higher levels of these endocrine-disrupting chemicals.
  • Results showed that plastic usage, such as bottled water and food containers, contributed to higher levels of bisphenols and phthalates in patients, highlighting the impact of dietary habits on chemical exposure.
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Biostimulants Enhance the Nutritional Quality of Soilless Greenhouse Tomatoes.

Plants (Basel)

September 2024

Institute of Plant Sciences and Resource Conservation, Division of Horticultural Sciences, University of Bonn, 53113 Bonn, Germany.

The application of biostimulants in vegetable cultivation has emerged as a promising approach to enhance the nutritional quality of crops, particularly in controlled environment agriculture and soilless culture systems. In this study, we employed a rigorous methodology, applying various biostimulants amino acids, Plant Growth-Promoting Rhizobacteria (PGPR), fulvic acid, chitosan, and vermicompost along with mineral fertilizers, both foliar and via the roots, to soilless greenhouse tomatoes during spring cultivation. The experiment, conducted in a coir pith medium using the 'Samyeli F1' tomato cultivar, demonstrated that plants treated with biostimulants performed better than control plants.

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Exercise Barriers in Older Individuals with Alzheimer's Disease: A Cross-Sectional Study.

Medicina (Kaunas)

September 2024

Department of Physiotherapy and Rehabilitation, Faculty of Health Sciences, Çukurova University, 01330 Adana, Turkey.

Article Synopsis
  • - The study aimed to explore the exercise habits of older adults with Alzheimer's Disease (AD) to improve rehabilitation programs by identifying barriers to exercise and psychological factors.
  • - Conducted with 50 AD patients, various tests showed significant correlations between age, time since diagnosis, cognitive function, and exercise barriers/benefits.
  • - Findings indicated that cognitive health and physical function impact exercise perception, and individuals living with caregivers scored better on exercise benefits, suggesting the importance of support systems.
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Background And Objectives: There is no standardised approach to toilet training in children. This study aimed to determine the factors affecting the duration of toilet training in children aged 0-5 years and to develop a tool to assess the child's readiness to start toilet training.

Materials And Methods: This cross-sectional study was conducted on 409 children aged 0-5 years.

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Monitoring macroplastics in aquatic and terrestrial ecosystems: Expert survey reveals visual and drone-based census as most effective techniques.

Sci Total Environ

December 2024

Department of Sciences, University Roma Tre, Viale Guglielmo Marconi 446, 00146 Rome, Italy; National Biodiversity Future Center (NBFC), Università di Palermo, Piazza Marina 61, 90133 Palermo, Italy. Electronic address:

Article Synopsis
  • Anthropogenic litter, specifically plastic, significantly impacts ecosystems, and scientists from various fields are working together to assess and reduce these pollutants.
  • The research aimed to determine the best methods for monitoring macroplastic litter in rivers and oceans by surveying 46 researchers who evaluated different techniques such as visual census, drone surveys, satellite imagery, and GPS/GNSS trackers.
  • Results indicated that traditional visual census and drone use were the most favored methods (scoring 3.5 and 2.0), while satellite imagery and GPS trackers were less effective due to validation challenges and range limitations, with scores below 1.2.
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Background: Cardiac troponin I, a particular biomarker, is released into the bloodstream in response to myocardial injury.

Objectives: To evaluate perioperative changes in high-sensitivity cardiac troponin I (hs-cTnI) concentration during ovariohysterectomy in cats undergoing three different anaesthesia protocols.

Methods:  Twenty-one female mixed-breed cats owned by clients aged (2.

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Introduction: Reduced bedaquiline (BDQ) sensitivity to antimycobacterial drugs has been linked to mutations in the Rv0678, pepQ, and Rv1979c genes of Mycobacterium tuberculosis (MTB). Resistance-causing mutations in MTB strains under treatment may have an impact on novel BDQ-based medication regimens intended to reduce treatment time. Due to this, we investigated the genetic basis of BDQ resistance in Turkish TB patients with MTB clinical isolates.

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Background: The use of biochemical markers in ADHF is considered valuable both in the diagnosis and treatment of diseases and in follow-up. This study aimed to investigate the prognostic power of serum sST2 and NT-proBNP levels in predicting long-term mortality in patients with ADHF using serial measurement.

Methods: A total of 122 patients with ADHF were included in this prospective study.

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Aim: This study aimed to examine how dyspnea, cough, sleep disruption, anxiety, depression, and physiological factors affect the quality of life in newly diagnosed, untreated IPF patients.

Methods: This study is a multicenter observational study. Patients not receiving antifibrotic treatment were included.

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The introduction of non-native species across the world represents a major global challenge. Retracing invasion origin is an important first step in understanding the invasion process, often requiring detailed sampling within the native range. Insect species frequently host , a widespread endosymbiotic bacterium that manipulates host reproduction to increase infected female fitness.

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Health benefits and risks of fermented foods-the PIMENTO initiative.

Front Nutr

September 2024

Research Division Microbial Food Systems, Agroscope, Berne, Switzerland.

Article Synopsis
  • * Seven of the reviews will look into clinical and biological effects of FF on various health indicators across organ systems, while the other nine will explore broader topics like bioactive compounds, safety, and personalized nutrition related to FF.
  • * Each review will consist of a systematic analysis of human studies, insights into the mechanisms behind observed health outcomes, and characterization of the FF being studied, culminating in a strategic roadmap for future research in the field.
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