Guidelines for species descriptions of free-living aquatic nematodes: characters, measurements and their presentation in taxonomic publications.

Free-living aquatic nematodes are abundant, diverse and of general environmental importance. However, knowledge of species distributions of both marine and freshwater nematodes is sparse. Species distribution data are crucial for evaluating environmental impacts from human activities and to conduct integrated nematode community assessments.

Coccinellidae (Coleoptera: Coccinelloidea) from Colombia: A systematic and illustrated list.

A synopsis of the family Coccinellidae of Colombia is presented, including an annotated list of the species recorded in the country based on published data, a revision of national and foreign collections, and information obtained from citizen science. The list includes 404 species grouped in 81 genera, 21 tribes and two subfamilies. There are 395 native species recorded (among them 201 considered endemic), and nine introduced.

Type catalogue of Hymenoptera (Insecta) housed in the Museo Nacional de Historia Natural de Cuba.

A total of 26 holotypes and 125 paratypes of Hymenoptera housed in the Museo Nacional de Historia Natural de Cuba are catalogued. Original publications were reviewed to compile all accompanying information and verify the status of the material. Data on the specimens are provided, grouped by families, and holotypes were photographed, making them more accessible for study by the scientific community.

On Perry O. Simons' 1899 collecting locality "Porvenir" in Ecuador.

The locality of Porvenir, sensu the collecting locality of Perry O. Simons (1869-1901), is geolocated, and approximate coordinates are provided, along with a map showing a number of other important nearby sites also visited by Simons and referenced in the historical zoological literature. Discussion on the incongruent coordinates for this locality mentioned in a number of previous works is provided.

A bibliographic review of the Chelodesmidae of the Antilles and Bahamas (Diplopoda: Polydesmida).

Among millipede groups found in the Antilles, the family Chelodesmidae is the most species diverse and well represented in collections. However, to date, there has not been a bibliographic review of the family for the region. Here we compile and review the literature for the Chelodesmidae of the Antilles and the Bahamas, clarify the family's status for the region, and discuss the central deficits of its taxonomy and the most relevant obstacles for work in the group.

TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine-1-Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects.

Current anti-epileptic drugs lack efficacy, cause many side effects and one third of all patients are treatment-resistant. Drugs targeting the sphingosine-1-phosphate receptor show potential anti-convulsant effects in animal models and decrease cortical excitability in patients with multiple sclerosis, but available compounds alter lymphocyte trafficking and cause immunosuppression, limiting their clinical anti-epileptic potential. TRV045 is a selective sphingosine-1-phosphate subtype 1 receptor agonist without effects on lymphocyte trafficking, demonstrating efficacy in animal models of epilepsy, with the potential to target abnormal cortical excitability.

Formation of hollow silver nanoparticles under irradiation with ultrashort laser pulses.

We have studied the formation of cavities in spherical silver nanoparticles embedded in silica, irradiated with fs laser pulses that produce an intense electronic excitation. Experimentally determined aspect ratio, i.e.

Assessment of molecular modulation by multifrequency electromagnetic pulses to preferably eradicate tumorigenic cells.

Physics methods of cancer therapy are extensively used in clinical practice, but they are invasive and often confront undesired side effects. A fully new equipment that allows sustained emission of intense and time-controlled non-ionizing multifrequency electromagnetic pulse (MEMP), has been applied to eukaryotic cells in culture. The equipment discriminates the overall electronegative charge of the cell cultures, and its subsequent proportional emission may thereby become higher and lethal to cancer cells of generally high metabolic activity.

Differential impact of infection on the microbiota of and .

The Western honey bee () is a vital agricultural pollinator whose populations are threatened by the parasitic mite destructor and associated pathogens. While the impact of species on honey bees, particularly larvae causing American foulbrood, is documented, their effect on the microbiota of mites remains unclear. This study aimed to investigate the influence of sp.

Fellowship education in epilepsy in Latin America and Africa: Results of a survey.

A large proportion of those affected by epilepsy live in resource-poor areas. The Epilepsy surgery in low-resource settings Task Force from the ILAE undertook a survey in Africa and Latin America to identify fellowships in Epilepsy and EEG as well as in Epilepsy Surgery. The results revealed a significant shortage of training programs in these two regions of the globe.

Obtaining HBV core protein VLPs carrying SARS-CoV-2 nucleocapsid conserved fragments as vaccine candidates.

The Hepatitis B core antigen (HBcAg) has been used as a carrier of several heterologous protein fragments based on its capacity to form virus-like particles (VLPs) and to activate innate and adaptive immune responses. In the present work, two chimeric proteins were designed as potential pancorona vaccine candidates, comprising the N- or C- terminal domain of SARS-CoV-2 nucleocapsid (N) protein fused to HBcAg. The recombinant proteins, obtained in E.

The effect of binaural pulse modulation (B.P.M) on brain state in depression and anxiety: a case series.

Objective: In this pilot study a binaural pulse modulator was tested to see if it leads to a change in self-reported measures of distress. This binaural pulse modulator produces two frequencies that combine to create a binaural pulse to stimulate the nervous system through a differential auditory tone presentation and the response of the user can be adjusted to the appropriate target tone for effective treatment use. Each individual calibrated the binaural pulse to increase the level of emotion experienced while imagining an experience with a similar emotional valence or while engaged in a cognitive function while also listening to the sound.

A sandwich ELISA for the quantification of the anticancer peptide CIGB-552 in human plasma.

CIGB-552 is a synthetic anticancer peptide that has been evaluated in vitro and in vivo in lung and colon cancer models. To optimize therapy in the clinic, pharmacokinetic studies are necessary. Previously, a sandwich-type enzyme-linked immunosorbent assay (ELISA) had been developed by our working group for the quantification of CIGB-552 in biological matrices.

[More Doctors Program: characterizing the quality of primary care by the type of medical provision].

This study characterized the quality of primary care based on the responses of professionals and users, focusing on the type of physician - whether or not they were included in the More Doctors Program (PMM, acronym in Portuguese). A cross-sectional study was conducted applying the Quality and Strengthening of Primary Care Questionnaire to 149 physicians and 795 users in basic health units in Pernambuco State, Brazil, from February to November 2018. The present study used the concept of PMM provision which foresees the allocation of medical professionals to an areas of social vulnerability.

Percutaneous gastric embolization for obesity: A prospective mid-term outcomes study.

Introduction: Obesity represents one of the most pressing public health challenges that needs to be solved globally, with serious health implications. Despite primary prevention efforts the prevalence of obesity continues to increase. Percutaneous gastric embolisation (PGE) has emerged as a promising technique in the management of this disease.

Development of bombesin-tubulysin conjugates using multicomponent chemistry to functionalize both the payload and the homing peptide.

Peptide-drug conjugates (PDCs) have recently gained significant attention for the targeted delivery of anticancer therapeutics, mainly due to their cost-effective and chemically defined production and lower antigenicity compared to ADCs, among other benefits. In this study, we designed and synthesized novel PDCs by conjugating new thiol-functionalized tubulysin analogs (tubugis) to bombesin, a peptide ligand with a relevant role in cancer research. Two tubulysin analogs bearing ready-for-conjugation thiol groups were prepared by an on-resin multicomponent peptide synthesis strategy and subsequently tested for their stand-alone anti-proliferative activity against human cancer cells, which resulted in IC values in the nanomolar range.

The Low-Density Lipoprotein Receptor-Related Protein-1 Is Essential for Dengue Virus Infection.

Dengue virus (DENV) causes the most prevalent and rapidly spreading arboviral disease of humans. It enters human cells by receptor-mediated endocytosis. Numerous cell-surface proteins were proposed as DENV entry factors.

Illumina Sequencing in Conjunction with Propidium Monoazide to Identify Live Bacteria After Antiseptic Treatment in a Complex Oral Biofilm: A Study Using an Ex Vivo Supragingival Biofilm Model.

: The evaluation of the efficacy of antibacterial treatments in complex oral ecosystems is limited by the inability to differentiate live from dead bacteria using omic techniques. The objective of this study was therefore to assess the ability of the combination of the 16S rRNA Illumina sequencing methodology and the action of propidium monoazide (PMA) to study viable bacterial profiles in oral biofilms after exposure to an antiseptic compound. : Cariogenic supragingival biofilms were developed in an ex vivo model for 96 h, using saliva from healthy volunteers.

Effects of 1-Deoxynojirimycin Extracts of Mulberry Leaves on Oxidative Stress and the Function of the Intestinal Tract in Broilers Induced by HO.

The poultry industry struggles with oxidative stress affecting gut health and productivity. This study examined using 1-Deoxynojirimycin (DNJ) extracts from mulberry leaves as an antioxidant in broilers feed to combat this issue. We divided 240 broilers, aged 16 days, into six groups, including a control and groups exposed to oxidative stress through HO injections, with different supplement levels of DNJ-E (40, 80, 120, and 160 mg/kg of the basal diet) lasting until the broilers reached 42 days old.

Do cooking techniques influence copper bioaccesibility in foods after in vitro digestion/fermentation in adults and children?

Cu is essential for the growth and organism health. Classically, its available fraction has been studied by in vitro digestion studies as a measure of bioaccessibility of Cu (Cu-BA). In this work we applied a novel in vitro digestion/fermentation method to multiple foods subjected to different home cooking techniques (raw form vs.