6 results match your criteria: "Critical Care and Pain Medicine Massachusetts General Hospital Harvard Medical School Boston[Affiliation]"
Introduction: Degradation in fractal motor activity regulation (FMAR), a measure of multiscale self-similarity of motor control, occurs in aging and accelerates with clinical progression to Alzheimer's disease (AD). Whether FMAR changes occur during the pre-symptomatic phase of the disease in women and men remains unknown.
Methods: FMAR was assessed in cognitively normal participants (n = 178) who underwent 7 to 14 days of home actigraphy.
Perspectives on Cardiopulmonary Critical Care for Patients With COVID-19: From Members of the American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation.
J Am Heart Assoc
July 2020
Anesthesia Center for Critical Care Research Department of Anesthesia Critical Care, and Pain Medicine Massachusetts General Hospital Harvard Medical School Boston MA.
Background Approximately 60% of women have Stage B heart failure 1 year after a preeclamptic delivery. Emerging evidence suggests that the profibrotic growth factor activin A, which has been shown to induce cardiac fibrosis and hypertrophy, is elevated in preeclampsia and may be inhibited by aspirin therapy. We hypothesized that preeclamptic women receiving aspirin would have lower activin A levels and reduced global longitudinal strain (GLS), a sensitive measure of cardiac dysfunction, than women who do not receive aspirin.
View Article and Find Full Text PDFBackground Patients resuscitated from cardiac arrest ( CA ) have highly variable neurological, circulatory, and systemic ischemia-reperfusion injuries. After the initial hypoxic-ischemic insult, a cascade of immune and inflammatory responses develops and is often fatal. The role of the immune response in pathophysiological characteristics and recovery is not well understood.
View Article and Find Full Text PDFInhibition of HCN channel activity in the thalamus attenuates chronic pain in rats.
Neurosci Lett
September 2016
MGH Center for Translational Pain Research Department of Anesthesia, Critical Care and Pain Medicine Massachusetts General Hospital Harvard Medical School Boston, MA, 02114, United States. Electronic address:
Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels regulate neuronal excitability in both peripheral and central nerve systems. Emerging evidence indicates that HCN channels are involved in the development and maintenance of chronic pain. However, the impact of HCN channel activity in the thalamus on chronic pain has not been examined.
View Article and Find Full Text PDFLung metabolism during ventilator-induced lung injury: stretching the relevance of the normally aerated lung*.
Crit Care Med
April 2014
Service de Réanimation Médicale Hôpital Henri Mondor Assistance Publique-Hôpitaux de Paris Créteil, France; and Department of Anesthesia Critical Care and Pain Medicine Massachusetts General Hospital Harvard Medical School Boston, MA Department of Anesthesia Critical Care and Pain Medicine Massachusetts General Hospital Harvard Medical School Boston, MA.