1 results match your criteria: "Critical Care Center of Children's Hospital Affiliated to Shanghai Jiaotong University[Affiliation]"
Glucocorticoid receptor expression on acute lung injury induced by endotoxin in rats.
World J Emerg Med
September 2014
Pediatric Institute for Critical Illness Research, Critical Care Center of Children's Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200040, China.
Background: In cases of severe sepsis and septic shock, a series of pathophysiological changes lead to multiple organ dysfunction syndrome. This study aimed to investigate the expression of glucocorticoid receptor mRNA in the rat lung following endotoxin (LPS) induced shock.
Methods: Totally 56 SD rats were randomly divided into 4 groups: LPS shock group (n=16), LPS+vasoactive intestinal peptide group(VIP) group, (n=16), LPS+VIP+ glucocorticoid (GC) group, (n=16),and control group (n=8).