Dissolution Thermodynamics of the Solubility of Sulfamethazine in (Acetonitrile + 1-Propanol) Mixtures.

: Solubility is one of the most important parameters in the research and development processes of the pharmaceutical industry. In this context, cosolubility is one of the most used strategies to improve the solubility of poorly soluble drugs, besides allowing to identify some factors involved in the dissolution process. The aim of this research is to evaluate the solubility of sulfamethazine in acetotinitrile + 1-propanol cosolvent mixtures at 9 temperatures (278.

Third-Generation Therapies for the Management of Psychoactive Substance Use in Young People: Scoping Review.

Introduction: Third-generation therapies (TGTs) have been shown to be effective in the treatment of substance use behaviors in college-aged adolescents. These therapies are based on acceptance, mindfulness and psychological flexibility, which enable young people to change their Psychoactive Substance Use (PSU)-related behaviours, develop coping skills to manage difficult emotions and thoughts, reduce experiential avoidance and maintain long-term abstinence.

Objective: To explore the implementation and potential benefits of third-generation therapies, Acceptance and Commitment Therapy (ACT), Dialectical Behaviour Therapy (DBT) and Mindfulness, for the treatment of PSU in college youth.

Impact of the deep squat on articular knee joint structures, friend or enemy? A scoping review.

Background: The squat exercise has been shown to improve athletic performance. However, the use of the deep squat has been questioned due to claims that it may cause knee joint injuries. Therefore, the purpose of this scoping review was to synthesize existing literature concerning the impact of deep squats on knee osteoarticular health in resistance-trained individuals.

Solubility of Sulfamerazine in Acetonitrile + Ethanol Cosolvent Mixtures: Thermodynamics and Modeling.

Sulfamerazine (SMR) is a drug used as an antibacterial agent in the treatment of some pathologies, such as bronchitis, prostatitis and urinary tract infections. Although this drug was developed in 1945 and, due to its toxicity, was partially displaced by penicillin, due to the current problem of bacterial resistance, compounds such as SMR have regained validity. In this context, the thermodynamic study of SMR in cosolvent mixtures of acetonitrile (MeCN) + ethanol (EtOH) at nine temperatures (278.

Thermodynamic Assessment of the Pyrazinamide Dissolution Process in Some Organic Solvents.

Pyrazinamide is a first line drug used for the treatment of tuberculosis, a pathology that caused the death of more than 1.3 million people in the world during 2022, according to WHO, being a drug of current interest due to its relevance in pharmaceutical and medical sciences. In this context, solubility is one of the most important physicochemical parameters in the development and/or optimization of new pharmaceutical forms, so the present work aims to present a thermodynamic study of the solubility of pyrazinamide in nine organic solvents of pharmaceutical interest.

Intimate Partner Violence Attitudes: Who Tolerates the Most?

Aim: to identify whether demographic variables, the type and length of romantic relationships, and alcohol consumption were risk factors related to attitudes toward intimate partner violence (IPV).

Method: 723 adults filled the IPVAS and a demographic survey.

Results: women were less likely to accept control; participants with technical education were more likely to tolerate control and abuse; those with secondary education were at higher risk to accept physical violence, while participants aged 26-35 were at lower risk; people who were dating someone were at higher risk to tolerate control, but were at a lower risk to accept physical violence; and those who consume alcohol were more likely to accept abuse.

Musculoskeletal disorders, associated factors, and literature review for intervention according to gender.

Introduction: The relationship of risk factors with musculoskeletal disorders and their intervention is a topic of interest, given their prevalence among workers. Thus, analyzing risk factors from approaches such as the gender perspective may be an alternative.

Objectives: To analyze risk factors in a health entity with a high prevalence of musculoskeletal disorders in upper limbs and to describe possible intervention measures according to scientific evidence, from a gender perspective.

Health conditions in land transport workers and climate change. Exploratory systematic review.

A systematic exploratory review was carried out to describe the influence of climate change on the health conditions of land transport drivers, both physical and mental. Additionally, actions for the prevention of these complications are described. For the review, several databases, such as Science Direct, MEDLINE, Springer, PubMed, Redalyc, EBSCO, SciELO, and Scopus, were examined.

Disruptions in the food supply chain: A literature review.

Disruptions in the food supply chain are events that affect the flow of products and can be caused by extreme weather, natural disasters, conflicts, pandemics, and political situations, among others. These events can significantly impact food products' availability, quality, and cost, creating risks to the well-being of local populations and livelihoods. The specific literature on food supply chains needs to address other approaches to risk categorisation, which allow for establishing reference frameworks focused on the general classification of types of disruption and parameters related to solution methods.

Influence of sustainability in the positioning of the university brand: Study in universities in Medellín-Colombia.

The implementation of university sustainability affects brand perceptions by conferring attributes related to commitment and reputation, especially by students. The proper management of sustainability is related to an improvement in the university brand perceived by its stakeholders, including students. For this reason, this research aims to analyse whether university sustainability positively affects brand positioning among university students.

Is it possible to prevent the progression of mild cognitive impairment through non-pharmacological treatments?

Introduction: Mild cognitive impairment produces slight cognitive and motor disturbances without affecting daily life during aging, however, if this symptomatology is not controlled, the speed of deterioration can increase, and even some cases of dementia can appear in the elderly population.

Objective: To describe non-pharmacological therapies that seek to prevent, control and reduce the symptoms of mild cognitive impairment.

Methods: An initial search was carried out in the databases of PubMed, Lilacs, EBSCO, ScienceDirect, Taylor & Francis and ProQuest.

Experiences of grief and moral sentiments in survivors of the armed conflict in Medellín, Colombia.

The objective of the study is to understand the experience of grief and moral sentiments in survivors of the armed conflict in the city of Medellín, Colombia, through qualitative research. In total, 32 people affected by different victimising acts in the context of the armed conflict participated. There is a direct relationship between moral sentiments and the processes of handling and processing loss.

[Bioelectrical impedance vectors in the Colombian university population].

Introduction: body composition (BC) analysis is an essential element in clinical nutritional practice. Bioelectrical impedance is one of the most widely used techniques for estimating BC. Several approaches have been proposed to reduce the margin of error it presents, ensuring its application in all populations.

Thermodynamic Assessment of Triclocarban Dissolution Process in -Methyl-2-pyrrolidone + Water Cosolvent Mixtures.

Solubility is one of the most important physicochemical properties due to its involvement in physiological (bioavailability), industrial (design) and environmental (biotoxicity) processes, and in this regard, cosolvency is one of the best strategies to increase the solubility of poorly soluble drugs in aqueous systems. Thus, the aim of this research is to thermodynamically evaluate the dissolution process of triclocarban (TCC) in cosolvent mixtures of {-methyl-2-pyrrolidone (NMP) + water (W)} at seven temperatures (288.15, 293.

Effects of internet-based, psychosocial, and early medical interventions on professional burnout in health care workers: Systematic literature review and meta-analysis.

Background: The prevalence of professional burnout increased among healthcare workers during the coronavirus 2019 (COVID-19) pandemic, with negative effects on their mental health. Consequently, research interest in methods to decrease the prevalence of burnout and reduce the effects of burnout on healthcare workers has increased. Objective: This study was designed to evaluate the effects of Internet-based, psychosocial, and early medical interventions on professional burnout among healthcare workers.

A new genus and species of Agriotina Laporte, 1840(Coleoptera: Elateridae: Agriotini) from Colombia.

Here, we describe and illustrate a new genus of Elateridae from Cundinamarca, Colombia, Raphaellus Zurita-García, Morales-Perdomo & Martínez-Luque, n. gen., to accommodate the new species R.

Evolution of teaching in short-term courses: A systematic review.

Short-term courses are a useful tool for continuous training to update and deepen knowledge in various fields. In this article, we analyse the evolution of the teaching methods used in short-term courses through a systematic review conducted using the PRISMA methodology. The inclusion criteria for selecting articles were those that described the methodological structure of the teaching methods used in designing short-term courses.

[Factors associated with condom use among sex workers of venezuelan origin in ColombiaFatores associados ao uso de preservativo em profissionais do sexo de origem venezuelana na Colômbia].

Objective: To describe the factors that determine condom use in Venezuelan immigrant sex workers in Colombia.

Methods: A qualitative study was conducted with an interpretive hermeneutic approach, using semi-structured interviews developed in the Metropolitan Area of Aburrá Valley, Bogotá, and the Colombian coffee-growing region.

Results: Fifty-five interviews were conducted.

[Perceived impact on the artisanal miner's health from quinchias municipality (Colombia) by the use of cyanide and mercury in the amalgamation process of gold].

Objective: Determine the Perceived Impact on the Artisanal Miner's Health from Quinchía's Municipality (Colombia) by the Use of Cyanide and Mercury in the Amalgamation Process of Gold.

Methods: Quantitative, descriptive research in a sample of 28 active miners exposed to cyanide and mercury. The process of gold amalgamation was characterized, a survey of symptom perception was carried out and laboratory tests were carried out to detect the concentration of mercury and cyanide in blood.

Occupational health in the framework of the COVID-19 pandemic: a scoping review.

Objective: To collect the available evidence related to occupational health in the face of the introduction of the new SARS-CoV-2 coronavirus pandemic.

Methods: Scoping review developed from the Arksey and O'Malley framework. The search was performed in the databases PubMed, Academic Search Complete, Science Direct, Medline, Scopus, Web of Science and Google Scholar.

[Clinical practice, work and risks of physical therapy in the face of COVID-19].

This paper discusses the function of the physiotherapy against COVID-19: how does it work in the chest physiotherapy and workplace health and safety. These fields are considered leading and decisive to take care of health professionals. In general, they work under unsuitable conditions that raise the likelihood of virus transmission in the social and economic context.

[Estimation of serial interval and basic reproductive number for imported cases of COVID-19].

Objective: To estimate the serial interval and the basic reproduction number of COVID-19 between imported cases during the containment phase in Pereira-Colombia, 2020.

Method: A quantitative study was carried out to determine the transmission dynamics for COVID-19. Field epidemiological data were used, which included 12 laboratory-confirmed cases with RT-PCR for imported SARS-CoV-2 and their corresponding confirmed secondary cases, including family and social contacts.

RaspyControl Lab: A fully open-source and real-time remote laboratory for education in automatic control systems using Raspberry Pi and Python.

Currently, remote laboratories have gained relevance in engineering education as tools to support active learning, experimentation, and motivation of students. Nonetheless, the costs and issues regarding their implementation and deployment limit the access of the students and educators to their advantages and features such as technical and educational. In this line, this study describes a fully open-source remote laboratory in hardware and software for education in automatic control systems employing Raspberry Pi and Python language with an approximate cost of USD 461.