5 results match your criteria: "Corewell Health Beaumont University[Affiliation]"
Time structures of proton pencil beam scanning delivery on a microsecond scale measured with a pixelated semiconductor detector Timepix3.
J Appl Clin Med Phys
September 2024
Department of Radiation Oncology and Winship Cancer Institute, Emory University, Atlanta, Georgia, USA.
Article Synopsis
- This study examines the timing of proton beam delivery in radiation therapy using a non-invasive method with a pixelated semiconductor detector.
- The detector, AdvaPIX-Timepix3, recorded the arrival times and energies of secondary particles to analyze various time structures of the beam, achieving high precision in measurements.
- Results showed that the time switch parameters were measured with less than 1.5% uncertainty, providing valuable insights into proton spill rates and pulse repetition times for different types of accelerators.
Anticholinergic medications have long been a mainstay of overactive bladder (OAB) treatment. Oxybutynin, a first-generation anticholinergic, still accounts for more than half of all OAB medication prescriptions, despite associations with impaired memory and cognition, as well as mounting evidence that it may increase the risk of incident dementia. This review details the current literature regarding oxybutynin and cognition, including evidence from preclinical, clinical, and real-world studies that show that oxybutynin binds nonspecifically to muscarinic receptors in the brain and is associated with adverse cognitive outcomes.
View Article and Find Full Text PDFPreventing the 17-Year Gap in Overactive Bladder Prescribing Practices: The Need for Implementation Science.
Urol Pract
March 2024
Oakland University William Beaumont School of Medicine, Corewell Health Beaumont University Hospital, Royal Oak, Michigan.
The first investigation of spot-scanning proton arc (SPArc) delivery time and accuracy with different delivery tolerance window settings.
Phys Med Biol
October 2023
Department of Radiation Oncology, Corewell Health Beaumont University, Royal Oak, MI,48073, United States of America.
. To investigate the impact of various delivery tolerance window settings on the treatment delivery time and dosimetric accuracy of spot-scanning proton arc (SPArc) therapy..
View Article and Find Full Text PDFPurpose: It remains unknown whether or not short-term androgen deprivation (STAD) improves survival among men with intermediate-risk prostate cancer (IRPC) treated with dose-escalated radiotherapy (RT).
Methods: The NRG Oncology/Radiation Therapy Oncology Group 0815 study randomly assigned 1,492 patients with stage T2b-T2c, Gleason score 7, or prostate-specific antigen (PSA) value >10 and ≤20 ng/mL to dose-escalated RT alone (arm 1) or with STAD (arm 2). STAD was 6 months of luteinizing hormone-releasing hormone agonist/antagonist therapy plus antiandrogen.