328 results match your criteria: "Copperbelt University[Affiliation]"

Background: How common it is with the presence of human papillomavirus (HPV) in the healthy and diseased oral cavity is largely unknown for Africans. In this cross-sectional study we assessed the prevalence of oral HPV and the risk factors associated with HPV contraction including sexual practice in the urban and rural Zambian population.

Methods: Urban (N = 188) and rural (N = 211) Zambian adults aged 21 years and older living in Ndola and Mansa, respectively, were interviewed about demographical data, oral and coital sexual history and tobacco and alcohol use.

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Marburg Virus Reaches Rwanda: How Close Are We to a Vaccine Solution?

Int J Infect Dis

December 2024

Department of General Medicine and Surgery, College of Medicine and Health Sciences, University of Rwanda, Kigali, Rwanda. Electronic address:

Marburg virus disease (MVD) is a highly virulent and often fatal disease caused by the Marburg virus, a member of the Filoviridae family, closely related to the Ebola virus. Historically, outbreaks have been sporadic but lethal across various African countries, with high case fatality rates (CFRs). In 2023, significant outbreaks occurred in Tanzania and Equatorial Guinea, with CFRs of 62.

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This study investigated the role of fish in addressing food and nutrition security challenges in Southern Africa, focusing on 10 countries including Angola, Zambia, Malawi, Mozambique, Namibia, Botswana, Zimbabwe, Lesotho, Eswatini, and South Africa. It examined the current state of food and nutrition security, fish production, and fish consumption patterns. Additionally, the study investigated the challenges and opportunities to enhance fish production in these countries thereby enhancing food and nutrition security.

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Introduction: Overexposure to respirable crystalline silica (RCS) can lead to the development of silicosis and other respiratory diseases. The mine under study was reported to have the highest number of certified cases of pneumoconiosis in Zambia in 2015, and in 2008, a study revealed that 56% of the RCS samples exceeded 0.05 mg/m3.

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Article Synopsis
  • Researchers have identified a rising trend of zoonotic diseases in Zambia, a key transport hub in Southern Africa, where numerous pathogens from bats, rodents, and non-human primates pose public health risks.
  • A review of studies from 1990 to 2022 found that viruses were the most reported pathogens, with notable threats including Ebola, Marburg, and Hantavirus, though many findings are based on short-term investigations.
  • The study highlights a significant lack of surveillance for these diseases in humans and emphasizes the urgent need for improved monitoring and preventive measures to mitigate emerging infectious risks in the region.
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Assessment of catchment water resources allocation under climate change in Luwombwa sub-catchment, Zambia.

Heliyon

November 2024

Department of Land Resources Management and Environmental Protection, Mekelle University, P.O.Box 231, Mekelle, Ethiopia.

The uncertainty in climate change and high water demand pose pressure on the natural water resources supply. Not only does this require better understanding but also a call for immediate interventions, mitigation and adaptive measures. This study evaluates catchment water resources in the Luwombwa sub-catchment in Zambia through statistical analysis in the downscaling of past, present and future climatic variables from the CMIP6 climatic model.

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ticks: new hosts for phleboviruses.

Parasitology

November 2024

Department of Biomedical Sciences, School of Health Sciences, University of Zambia, Lusaka, Zambia.

Ticks are widespread arthropods that transmit microorganisms of veterinary and medical significance to vertebrates, including humans. , an ixodid tick frequently infesting and feeding on humans, may play a crucial role in transmitting infectious agents across species. Despite the known association of many ticks with phleboviruses, information on is lacking.

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Defining the bacterial microbiome of ticks in Chongwe and Chisamba Districts of Zambia.

Infect Med (Beijing)

December 2024

Department of Biomedical Sciences, School of Health Sciences, University of Zambia, P.O Box 50110, Lusaka 10101, Zambia.

Article Synopsis
  • The study investigates the tick microbiome in selected districts of Zambia to understand how it interacts with pathogens and influences tick behavior and disease transmission.
  • Researchers collected 94 ticks from cattle and used PCR and high-throughput sequencing to analyze the microbiome composition and detect pathogen prevalence.
  • Findings revealed a 47.9% prevalence of certain pathogens with significant variations in microbiome composition based on detection status and location, offering new insights into tick microbiomes in Zambia.
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Article Synopsis
  • - Human African trypanosomiasis is a severe neglected tropical disease that can be fatal without treatment, and the WHO has updated its treatment guidelines after a thorough review.
  • - Fexinidazole is now the preferred first-line treatment for patients aged 6 years and over who weigh at least 20 kg, eliminating the need for invasive lumbar punctures for staging the disease.
  • - While fexinidazole improves treatment options and reduces the risk of severe side effects from previous medicines, it remains unavailable for children who don't meet the age or weight criteria, making interim use of pentamidine necessary in some cases.
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In sub-Saharan Africa, limited studies have investigated zoonotic pathogens that may be harboured by ticks infesting reptiles such as tortoises. Here, we report the presence of pathogenic in ticks () collected from the leopard tortoise () in rural Zambia. Using polymerase chain reaction, 56% (49/87) of ticks were positive for the outer membrane protein () gene.

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Antimicrobial resistance (AMR) is a public health problem exacerbated by the overuse and misuse of antibiotics and the inadequate capacity of laboratories to conduct AMR surveillance. This study assessed the capacity of laboratories in seven faith-based hospitals to conduct AMR testing and surveillance in Zambia. This multi-facility, cross-sectional exploratory study was conducted from February 2024 to April 2024.

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Wastewater-based surveillance has emerged as an important method for monitoring the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). This study investigated the presence of SARS-CoV-2 in wastewater in Zambia. We conducted a longitudinal study in the Copperbelt and Eastern provinces of Zambia from October 2023 to December 2023 during which 155 wastewater samples were collected.

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Background: Understanding and exploring stakeholders' perceptions and preferences regarding comprehensive sexuality education (CSE) is critical in enhancing programme acceptability. We conducted this qualitative study to explore stakeholders' experiences and preferences of CSE in Kitwe district, Zambia.

Methods: We employed a qualitative descriptive design within the interpretive paradigm at nine purposefully selected secondary schools.

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Decades of illegal hunting (poaching) have adversely affected wildlife populations and thereby limited sustainable wildlife conservation in the Luangwa Valley, Zambia. Despite intervention efforts to address the problem, the illegal hunting of wildlife has persisted. Therefore, this study was conducted to understand the persistence of illegal hunting by investigating the drivers of poaching and intervention measures using a mixed methods approach.

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Introduction: Sepsis, a condition of global public health concern, is a major cause of morbidity and mortality, especially in patients with underlying HIV infection. This study aims to determine outcomes, aetiology and antibiotic resistance patterns among children with HIV exposure or infection admitted with a clinical presentation suggestive of sepsis who have confirmed bloodstream infections at Arthur Davison Children's Hospital (ADCH) in Ndola, Zambia.

Methods And Analysis: This will be a prospective longitudinal study of 200 children aged <2 years admitted with sepsis at ADCH with two of the following conditions: temperature of 38.

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A review of improvements on electric vehicle battery.

Heliyon

August 2024

Electrical Engineering Department, School of Engineering, Copperbelt University, Zambia.

The development of efficient and high-performance electric vehicle (EV) batteries relies on improving various components, such as the anode and cathode electrodes, separators, and electrolytes. This review paper offers an elaborate overview of different materials for these components, emphasizing their respective contributions to the improvement of EV battery performance. Carbon-based materials, metal composites, and polymer nanocomposites are explored for the anode, offering high energy density and capacity.

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Background: The neurological, airway, respiratory, cardiovascular and other, with a subscore of surgical severity (NARCO-SS) is a scoring system which assesses the presence of systemic disease and the risk the operation poses to the patient. A number of patients that undergo major abdominal surgery suffer adverse events. The aim of the study was to determine the reliability of NARCO-SS in predicting peri-operative adverse events and to determine the risk factors for peri-operative adverse events in paediatric patients undergoing elective abdominal surgery.

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Review of methods for alumina recovery from mudstone and coal fly ash.

Heliyon

July 2024

Chemical Engineering Department, School of Mines and Mineral Sciences, Copperbelt University, Zambia.

Developing recovery methods from coal mine waste like mudstone and coal fly ash (CFA) is crucial to expanding the alumina supply beyond bauxite. This review explores various approaches for alumina recovery from mudstone and CFA. Six main leaching techniques are discussed-caustic soda, nitric acid, Sulphuric acid, hydrochloric acid, and leaching roasted coal mine wastes.

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(Ebenaceae) is a valuable medicinal plant that grows in the wild in Zambia. The aqua crude plant extract is valuable in treating oxidative stress and microbes-related diseases. In this study, bioactive metabolites from the leaf of the plant were tentatively identified using ultra-high-pressure liquid chromatography tandem high-resolution mass spectrometry (UHPLC-HRMS).

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