54 results match your criteria: "Copenhagen University Hospital - Rigshospitalet - Glostrup.[Affiliation]"

The study objective was to examine natural variation of the patient-reported outcome measures fatigue, pain, patient global assessment (PaGl) and the Bath Ankylosing Spondylitis Functional Index (BASFI) in patients with stable axial spondyloarthropathy (ax-SpA) defined on the basis of the Bath Spondylitis Ankylosing Disease Activity Index (BASDAI). 107 TNF-inhibitor treated stable ax-SpA patients were identified in the Danish rheumatology registry (DANBIO). According to the Assessment of SpondyloArthritis international Society (ASAS) response criteria, stable disease was defined as a change in BASDAI < 20 between two consecutive visits.

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Background: Although dementia is associated with both global and regional cerebral blood flow (CBF) changes, little is known about cerebral perfusion in the early pre-clinical stages of cognitive decline preceding overt cognitive dysfunction. The aim of this study was to investigate the association of early sub-clinical cognitive decline with CBF.

Materials And Methods: The study participants were recruited from a cohort of Danish men born in 1953.

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Article Synopsis
  • The study aimed to compare mean global cerebral blood flow (CBF) between two imaging techniques: O-H O positron emission tomography (PET) and phase-contrast mapping magnetic resonance imaging (PCM MRI) in healthy individuals.
  • Conducted on 22 young male volunteers, the study involved simultaneous measurements of CBF, revealing that while both methods showed a significant correlation, PCM MRI consistently yielded higher CBF values than PET.
  • The findings suggest that PCM MRI can quantify global CBF, but it may have methodological biases leading to inflated measurements compared to the PET reference.
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Purpose: Both [(18)F]-fluoroethyltyrosine (FET) PET and blood volume (BV) MRI supplement routine T1-weighted contrast-enhanced MRI in gliomas, but whether the two modalities provide identical or complementary information is unresolved. The aims of the study were to investigate the feasibility of simultaneous structural MRI, BV MRI and FET PET of gliomas using an integrated PET/MRI scanner and to assess the spatial and quantitative agreement in tumour imaging between BV MRI and FET PET.

Methods: A total of 32 glioma patients underwent a 20-min static simultaneous PET/MRI acquisition on a Siemens mMR system 20 min after injection of 200 MBq FET.

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