731 results match your criteria: "Cooling Techniques for Hyperthermia"
Late gestation heat stress alters O regulation in placenta and neonatal heifers.
Placenta
December 2024
Department of Animal Sciences, University of Florida, Gainesville, USA. Electronic address:
Introduction: Maternal hyperthermia (i.e. heat stress) can adversely affect placental development and function, with severity varying based on pregnancy stage.
View Article and Find Full Text PDFExertional Heatstroke Encephalopathy With Chronic Neurological Deficit.
Cureus
October 2024
General Medicine, Dr. D Y Patil Medical College, Hospital and Research Centre, Dr. D Y Patil Vidyapeeth (Deemed to be University), Pune, IND.
Heat exhaustion progresses to heat stroke and then on to heatstroke encephalopathy, a serious illness. Extreme hyperthermia (over 40.5 °C), central nervous system failure, multiorgan dysfunction, and hypovolemic shock are the hallmarks of the clinical presentation of heatstroke.
View Article and Find Full Text PDFTemperature and state-dependent electrical conductivity of soft biological tissue at hyperthermic temperatures.
Int J Hyperthermia
November 2024
Department of Mechanical Science and Engineering, University of Illinois Urbana-Champaign, Urbana, IL, USA.
We present a physics-based, temperature and state-dependent electrical conductivity model for soft biological tissue under thermal therapies with a quantified damage parameter that represents the state of soft biological tissue (degree of denaturation). Most existing models consider electrical conductivity to be only temperature-dependent and evaluate tissue damage during post-processing after temperature calculation. Our model allows tissue damage to be coupled into the thermal model for a more accurate description of both RF ablation and electrosurgery.
View Article and Find Full Text PDFNovel ryanodine receptor 1 (RYR1) missense gene variants in two pet dogs with fatal malignant hyperthermia identified by next-generation sequencing.
Vet Anaesth Analg
October 2024
Comparative Pharmacogenomics Laboratory, Program in Individualized Medicine, Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman, WA, USA. Electronic address:
Objective: Evaluate a precision medicine approach to confirm a tentative diagnosis of fatal malignant hyperthermia (MH) in isoflurane-anesthetized pet dogs by identifying novel risk variants in known MH susceptibility genes.
Study Design: Retrospective case series.
Animals: A male Pit Bull mix aged 7 years (case #1), a male Golden Retriever aged 12 months (case #2) and the dam and sire of case #2.
Risk factors of early death in heat stroke and the challenges of emergency care in Hungary - a case series study.
Int J Emerg Med
October 2024
Department of Emergency Medicine, Semmelweis University, 1085 Budapest, Üllői út 26, Budapest, Hungary.
Article Synopsis
- The study investigates heat stroke cases at an academic emergency department in Hungary, focusing on clinical features, treatment options, and early outcomes amid increasing heat wave occurrences.
- Analyzed data from eight patients revealed that three patients died, with significant differences in key laboratory values such as pH, potassium, and lactate between those who survived and those who did not.
- The research suggests that elevated heat stress due to climate change may increase heat stroke risks in temperate regions, highlighting the need for improved diagnostic and therapeutic standardization to lower mortality rates.
Effects of normal saline versus lactated Ringer's solution on organ function and inflammatory responses to heatstroke in rats.
J Intensive Care
October 2024
Nursing Department, The Second Affiliated Hospital of Zhejiang University School of Medicine, 88 Jiefang Road, Shangcheng District, Hangzhou, 310009, Zhejiang, China.
Article Synopsis
- Heatstroke is a serious condition that leads to high body temperatures and can damage organs, and this study aims to understand how two types of fluid treatments, normal saline (NS) and lactated Ringer's solution (LR), affect inflammation and organ health during heatstroke recovery in rats.
- In the study, male rats were divided into groups receiving either NS or LR after experiencing heatstroke, or as controls without heat exposure. Measurements included vital signs, inflammation levels, and kidney and heart function indicators.
- Results indicated that rats treated with NS after heatstroke showed worse health outcomes, including lower blood pressure and higher levels of inflammatory substances, compared to those treated with LR, suggesting that LR might be more effective in managing heatstroke symptoms
Voluntary head dunking after exercise-induced hyperthermia rapidly reduces core body temperature in dogs.
J Am Vet Med Assoc
December 2024
1Penn Vet Working Dog Center, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA.
Article Synopsis
- - The study aimed to identify effective cooling methods for dogs suffering from exercise-induced hyperthermia, testing four different techniques after the dogs reached a critical core temperature or showed signs of heat stress.
- - Results indicated that the "dunking" method, where dogs were briefly submerged in cool water, resulted in the fastest cooling effects and prevented a rise in temperature immediately after exercise.
- - The findings suggest that quickly cooling dogs in the field is crucial; if immersion isn't feasible, controlled water intake and head cooling can help but need more investigation.
Multifrequency operation of an intracavitary monopole with sliding broadband choke for delivering hyperthermia treatment with variable coverage.
Electromagn Biol Med
October 2024
Department of Engineering Design, Indian Institute of Technology Madras, Chennai, India.
Microwave applicators reported for intracavitary hyperthermia (HT) operate at single frequency and deliver fixed treatment coverage at the tumor target. In this work, we report multifrequency operation of a water-cooled monopole antenna with a sliding broadband ferrite choke for delivering intracavitary HT to the cervix with variable spatial coverage. Spatially varying treatment coverage is achieved by varying the choke position with respect to the monopole using a mechanical sliding arrangement and exciting the antenna at the modified resonant frequency.
View Article and Find Full Text PDFMagnetic-Nanorod-Mediated Nanowarming with Uniform and Rate-Regulated Heating.
Nano Lett
September 2024
Department of Chemistry, University of California, Riverside, California 92521, United States.
Article Synopsis
- Rewarming cryopreserved samples requires quick heating to prevent devitrification, a challenge addressed by using FeO@SiO nanorods for controlled heating.
- These nanorods can be aligned in a cryoprotective agent during cooling, allowing for rapid and even rewarming when subjected to an alternating magnetic field.
- By applying an orthogonal static magnetic field later, the method prevents overheating and reduces toxic effects of the cryoprotective agent, improving sample rewarming uniformity as demonstrated in gel and porcine artery models.
Rebound Hyperthermia in Exertional Heat Stroke.
Mil Med
August 2024
The Army Heat Center, Martin Army Community Hospital, Fort Moore, GA 31905, USA.
Article Synopsis
- Exertional heat stroke (EHS) is a serious condition that requires quick cooling to avoid health issues, with a recommended cooling rate of 0.15°C/min.
- A case report on a 22-year-old man shows that after initial cooling, he faced rebound hyperthermia, leading to the use of endovascular cooling (EVC) for effective temperature regulation.
- This case highlights the importance of immediate cooling in EHS and suggests a need for specific EVC protocols for cases with rebound hyperthermia.
Generating and monitoring mild hyperthermia using a ring array ultrasound transducer.
Int J Hyperthermia
August 2024
Department of Biomedical Engineering, Hajim School of Engineering and Applied Sciences, University of Rochester, Rochester, New York, USA.
Article Synopsis
- The study aims to explore the use of a ring array ultrasound (US) transducer with ultrasound tomography (UST) for creating and monitoring mild hyperthermia (MHTh).
- Experiments showed that the ring array US transducer provided effective temperature management and achieved better acoustic focusing when controlled by UST, improving performance in diverse tissue types.
- Results indicated that this US transducer can safely and accurately generate and track MHTh, suggesting a promising advancement in non-invasive, temperature-controlled treatment options.
Ultrasound-MR fusion imaging combined with intraductal cooling via PTCD during microwave ablation of perihilar liver tumors: a retrospective pilot study.
Int J Hyperthermia
July 2024
Department of Medical Ultrasonics, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, China.
Article Synopsis
- The study explores the safety and effectiveness of a new technique combining microwave ablation (MWA) with intraductal chilled saline perfusion (ICSP) and ultrasound-magnetic resonance fusion imaging to treat liver tumors near the hilar bile ducts (HBDs).
- A retrospective analysis of 12 patients who underwent this procedure showed high rates of technical success and efficacy, with minimal complications, including one case of biliary infection.
- The findings suggest that this combined approach is a feasible and safe option for treating liver tumors located very close to the HBDs, improving treatment possibilities in such challenging cases.
Servo-controlled therapeutic hypothermia during neonatal transport: a before-and-after quality improvement project.
Eur J Pediatr
October 2024
Division of Pediatrics and Neonatal Critical Care, SMUR Pédiatrique 92, "Antoine Béclère" Hospital, Paris Saclay University Hospitals, APHP, Paris, France.
Article Synopsis
- The paper compares the effectiveness of servo-controlled hypothermia (CTH) versus passive hypothermia in neonates with encephalopathy during transport, highlighting improvements in temperature management with CTH.
- In the study, 100% of infants who received CTH reached the target temperature upon NICU arrival, contrasted with only 32% of those in passive hypothermia.
- Findings suggest that CTH does not delay NICU arrival compared to passive methods, and there was no significant difference in short-term outcomes between the two groups.
Magnetic resonance thermometry for hyperthermia in the oropharynx region.
Int J Hyperthermia
July 2024
Department of Radiology and Nuclear Medicine, Erasmus MC, University Medical Center Rotterdam, Rotterdam, the Netherlands.
Article Synopsis
- Magnetic resonance thermometry (MRT) allows real-time, non-invasive measurement of temperature changes in the oropharynx and head and neck, but motion during long treatments may create artifacts.
- This study evaluated MRT's feasibility for hyperthermia treatments by analyzing its performance during breath-hold and swallowing scans on five volunteers over approximately 75 minutes.
- Results showed no significant differences in MRT performance due to breathing or swallowing, but indicated that different regions of interest (ROI) had varying accuracy, with neck muscle performing best in terms of mean average error (MAE) and standard deviation (SD).
Article Synopsis
- - This research examined how heat affects the upper body of firefighters and their protective gear after intense heat exposure, confirming a hypothesis that the head and helmet would be the hottest areas.
- - Twenty participants exercised for 21 minutes in a humid and hot environment while wearing firefighter gear, with various body parts and PPE analyzed for temperature.
- - Results showed the head, chest, and upper back were the hottest post-exercise, while the abdomen was the coolest, highlighting the need for better cooling strategies for firefighters.
Case Report of the Use of an Intravascular Cooling Device in the Management of Malignant Hyperthermia.
Ther Hypothermia Temp Manag
June 2024
Department of Emergency Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Article Synopsis
- Malignant hyperthermia (MH) is a serious inherited condition triggered by certain anesthetic agents, leading to rapid muscle rigidity and potential hyperthermia due to calcium channel issues in skeletal muscles.
- Quick diagnosis is crucial for reducing mortality, and treatment involves stopping the triggering agents and administering dantrolene, alongside supportive care such as cooling.
- The case report presents a patient with MH who was successfully treated using invasive intravenous cooling, marking an innovative approach not previously described in similar conditions.
Association of temperature management strategy with fever in critically ill children after out-of-hospital cardiac arrest.
Front Pediatr
April 2024
Pediatric Critical Care Medicine, Children's National Hospital, Washington, DC, United States.
Article Synopsis
- The study aimed to see if different ICU temperature management strategies impact fever occurrence in children who have returned to spontaneous circulation after a cardiac arrest outside the hospital.
- A total of 111 children were observed, and it was found that about 51% developed a fever within 72 hours of admission.
- The results suggested that using a homeothermic blanket significantly reduced fever risk compared to passive management, indicating that temperature management strategies can influence fever incidence in critically ill children.
Post-exercise management of exertional hyperthermia in dogs participating in dog sport (canicross) events in the UK.
J Therm Biol
April 2024
Pathobiology and Population Sciences, The Royal Veterinary College, Hawkshead Lane, North Mymms, Hatfield, Herts, AL9 7TA, UK.
Article Synopsis
- Exercise is a major cause of heat-related illness (HRI) in dogs, responsible for 74% of cases treated in the UK; there is limited research on effective cooling methods for affected dogs.
- The study monitored temperature changes in dogs after canicross events, evaluating various cooling practices and ambient conditions, finding that many dogs still increased in temperature shortly after exercise.
- Results suggest that cold-water immersion effectively cools hyperthermic dogs, emphasizing the importance of cooling dogs before transportation to prevent further temperature increases.
Body Bag Cooling with Two Different Water Temperatures for the Treatment of Hyperthermia.
Aerosp Med Hum Perform
April 2024
Article Synopsis
- Exertional heatstroke (EHS) is a serious and potentially life-threatening condition that needs immediate cooling to lower body temperature for survival.
- A study tested the effectiveness of using a body bag filled with water at different temperatures (10°C and 15°C) to cool individuals suffering from EHS and found that the cooling rates met acceptable standards, with faster cooling in the 10°C water.
- The results indicate that body bag cooling could be a practical treatment for EHS when access to ice or ice water is limited, providing clinicians with an alternative approach.
Integrable Magnetic Fluid Hyperthermia Systems for 3D Magnetic Particle Imaging.
Nanotheranostics
March 2024
Fraunhofer Research Institution for Individualized and Cell-Based Medical Engineering (IMTE), Lübeck, Germany.
Article Synopsis
- Combining magnetic particle imaging (MPI) and magnetic fluid hyperthermia (MFH) enables targeted heating in the body and improved monitoring of treatment without surgery.
- The paper presents a new design for MFH systems that can be integrated into existing MPI scanners, overcoming challenges like magnetic interference that could damage the imaging equipment.
- The developed integrable platforms ensure safe magnetic and electrical operations, allowing for precise heating techniques and enhancing the potential for future medical trials involving advanced cancer treatments.
The Effect of Body Temperature Changes on the Course of Treatment in Patients With Pneumonia and Sepsis: Results of an Observational Study.
Interact J Med Res
March 2024
Medical Intensive Care Unit, University Medical Centre Maribor, Maribor, Slovenia.
Article Synopsis
- Critically ill patients traditionally receive antipyretics to reduce fever, but recent evidence suggests that lowering body temperature may not improve treatment outcomes and that increasing body temperature could actually be beneficial.
- This study investigates how body temperature affects the treatment of mechanically ventilated patients with pneumonia and sepsis in the ICU by analyzing temperature and treatment parameters within the first 48 hours of admission.
- Results show that patients who survived to discharge had higher average temperatures in the first 48 hours than those who did not survive, although temperature did not significantly correlate with the duration of mechanical ventilation.
The impact of ischemic vascular stenosis on LIPU hyperthermia efficacy investigated Based on in vivo rabbit limb ischemia model.
Ultrasonics
March 2024
Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Modern Acoustics (MOE), Department of Physics, Collaborative Innovation Center of Advanced Microstructure, Nanjing University, Nanjing 210093, China; The State Key Laboratory of Acoustics, Chinese Academy of Science, Beijing 10080, China. Electronic address:
Article Synopsis
- * This study used a rabbit model to examine changes in blood vessels and temperature during low-intensity pulsed ultrasound (LIPU) treatment after surgically inducing limb ischemia.
- * Findings showed a significant reduction in artery diameter and blood flow, indicating that this model can help understand how LIPU affects heating in ischemic tissues, which is crucial for creating safe and effective ultrasound treatment protocols for patients.
Intraoperative tourniquet-induced hyperthermia in a pediatric patient: a forgotten association -a case report.
Korean J Anesthesiol
June 2024
Department of Anesthesiology, ICU and Perioperative Medicine, Hamad Medical Corporation, Doha, Qatar.
Article Synopsis
- The first reported case of tourniquet-induced hyperthermia occurred in a 5-year-old female patient undergoing surgery for congenital foot deformity.
- After a pneumatic tourniquet was inflated on her thigh, her body temperature rose despite cooling efforts, only stabilizing once the tourniquet was released.
- The case highlights the need for healthcare professionals to recognize tourniquet-induced hyperthermia as a possible issue during surgeries and to manage it promptly to avoid complications.
Factors influencing deviation from target temperature during targeted temperature management in postcardiac arrest patients.
Open Heart
December 2023
Trauma and Acute Critical Care Center, Tokyo Medical and Dental University Hospital, Bunkyo-ku, Tokyo, Japan.
Article Synopsis
- Targeted temperature management (TTM) is essential for improving outcomes in postcardiac arrest patients, with a specific focus on avoiding hyperthermia and overcooling.
- A study was conducted comparing conventional and modified TTM protocols, revealing that the modified protocol led to less temperature deviation and required more neuromuscular blocking agents.
- Ultimately, the results suggested that a target temperature of 35°C is both acceptable and achievable, with specific factors (like age and cooling methods) influencing temperature consistency.
A Randomized Cross-Over Study Comparing Cooling Methods for Exercise-Induced Hyperthermia in Working Dogs in Training.
Animals (Basel)
November 2023
Penn Vet Working Dog Center, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19146, USA.
Article Synopsis
- Working dogs are at risk for a serious condition called non-pyrogenic hyperthermia, which can arise from hard work or hot environments.
- A study tested the effectiveness of two cooling methods: water immersion and applying isopropyl alcohol to dogs' paws, comparing them with no cooling intervention.
- Results indicated that both water immersion and isopropyl alcohol were effective in cooling the dogs, but water immersion was more effective and less stressful, as applying alcohol increased heart rates.