16,889 results match your criteria: "Contusions"

Pediatric neck injuries associated with trampoline use.

Am J Otolaryngol

December 2024

Department of Otolaryngology-Head and Neck Surgery, Jacobs School of Medicine and Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14209, USA. Electronic address:

Objective: Trampolines are popular among children, but trampoline injuries constitute a large number of emergency department visits. The purpose of this study was to determine how often neck injuries occur among children with trampoline-related injuries and to identify the mechanism of injury.

Methods: We analyzed the National Electronic Injury Surveillance System (NEISS) database to characterize patient demographics, injury types, injury subsite, and emergency department disposition status associated with trampoline related neck injuries between 2012 and 2021 in the United States.

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Background: Residual back pain (RBP) is one of the complications following percutaneous vertebroplasty (PVP) in older people with osteoporotic vertebral compression fractures (OVCFs). The vertebral bone quality (VBQ) score obtained from magnetic resonance imaging (MRI) can be used to evaluate bone quality. The objective of this study aimed to explore the potential relationship between the VBQ score and RBP after PVP.

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Background: Pharyngeal perforation has been documented as a consequence of substantial external force applied to the neck. Such trauma is frequently accompanied by additional organ injury and cervical fracture. In this report, we present an exceptionally rare instance in which minor blunt trauma to the neck resulted in pharyngeal injury without concomitant damage to other organs.

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Evolution of Lipid Metabolism in the Injured Mouse Spinal Cord.

J Neurotrauma

December 2024

Department of Pharmacology and Toxicology, College of Pharmacy, University of Arizona, Tucson, Arizona, USA.

Following spinal cord injury (SCI), there is a short-lived recovery phase that ultimately plateaus. Understanding changes within the spinal cord over time may facilitate targeted approaches to prevent and/or reverse this plateau and allow for continued recovery. Untargeted metabolomics revealed distinct metabolic profiles within the injured cord during recovery (7 days postinjury [DPI]) and plateau (21 DPI) periods in a mouse model of severe contusion SCI.

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Beyond the Barriers of Ex Vivo Lung Perfusion Through an Emblematic Case: A New Way Forward to Expand the Donor Pool.

J Clin Med

December 2024

Thoracic Surgery Unit, Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, 35128 Padua, Italy.

Lung transplantation is the most effective treatment for end-stage respiratory diseases, but its application is limited by the shortage of organs. Ex vivo lung perfusion (EVLP) has emerged as a promising technique to evaluate and recondition donor lungs previously deemed unsuitable for transplantation. However, limitations such as lung contusions, air leaks, and perfusate extravasation, especially in portable EVLP systems, hinder the procedure.

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Delayed cardiac tamponade following blunt chest trauma is a rare incident, and we provide a report including a literature review for further discussion. The patient is a 56-year-old male. He fell off a motorcycle and sustained contusions to the left side of his chest.

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Introduction: Elbow joint is the most common affliction in upper limb tuberculosis (TB). A review of literature shows varying clinical presentations of TB in the elbow, with and without detectable primary foci.

Case Report: We report a rare case of post-traumatic reactivation of latent TB of elbow which mimicked septic arthritis, in a healthy adult who suffered an elbow contusion injury following an road traffic accident.

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Epidural electrical stimulation combined with photobiomodulation restores hindlimb motor function in rats with thoracic spinal cord injury.

Exp Neurol

December 2024

Beijing Key Laboratory for Biomaterials and Neural Regeneration, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, Beihang University, Beijing 100191, China. Electronic address:

Epidural electrical stimulation (EES) could restore motor function of paralyzed limbs of patients with spinal cord injury (SCI). However, its invasiveness limits its application in early stage of injury. Photobiomodulation (PBM) utilizes infrared light for percutaneous irradiation of the spinal cord to protect nerve tissue, delay muscle atrophy, and can be applied in early stage of SCI due to its non-invasiveness.

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Article Synopsis
  • The study investigates the potential development of intraspinal pressure (ISP) elevation following traumatic spinal cord injury (TSCI) in a porcine model, particularly focusing on a hypothesized subdural compartment syndrome.
  • Researchers conducted a randomized, sham-controlled trial over 72 hours measuring ISP changes alongside various injury protocols to assess the impact of different contusion regimes on ISP.
  • Results showed no significant difference in ISP increases between TSCI and sham animals, indicating that the observed ISP changes were likely due to the surgical procedures rather than TSCI itself.
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Introduction: Judo, a martial art created by Jigoro Kano in 1882, is a martial art promoting physical and spiritual development. Despite its "gentle way" philosophy, it poses a significant risk for cervical spine injuries, often resulting from throws and ground techniques.

Methods: This cross-sectional study analyzed cervical injuries among professional judo athletes from January to July 2024.

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Cervical spinal cord injury usually leads to cardiorespiratory dysfunction due to interruptions of the supraspinal pathways innervating the phrenic motoneurons and thoracic sympathetic preganglionic neurons. Although clinical guidelines recommend maintaining the mean arterial pressure within 85-90 mmHg during the first week of injury, there is no pre-clinical evidence from animal models to prove the therapeutic efficacy of hemodynamic management. Accordingly, the present study was designed to investigate the therapeutic efficacy of hemodynamic management in rats with cervical spinal cord contusion.

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Background: Polytrauma and hemorrhagic shock can lead to direct and indirect liver damage involving intricate pathophysiologic mechanisms. While hepatic function has been frequently highlighted, there is minimal research on how the receptor activator of the NF-κB (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) system is regulated in the liver following trauma. Furthermore, cross-talking complement and toll-like-receptor (TLR) systems can contribute to the posttraumatic response.

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Systemic administrations of protamine heal subacute spinal cord injury in mice.

Neurosci Res

December 2024

Department of Biochemistry, Nagoya University Graduate School of Medicine, 65 Tsurumai-cho, Showa-ku, Nagoya 466-8550, Japan; Institute for Glyco-core Research (iGCORE), Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8601, Japan. Electronic address:

Spinal cord injury (SCI) results in damage to neural circuits that cause long-term locomotor and sensory disability. The objective of the present study is to evaluate whether a clinical drug, protamine, can be employed as a therapeutic agent for SCI. First, we examined the rescue effect of protamine on dystrophic endballs (DEs) cultured on a chondroitin sulfate (CS) gradient coating.

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Purpose: Orotracheal intubation is one of the most frequently used techniques in emergency procedures and especially in anesthesia and resuscitation. Teeth may be "victims" of the orotracheal intubation. Several factors may predispose to these accidents.

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Article Synopsis
  • Traditional classifications of astrocytes include fibrous and protoplasmic types, but GFAP (glial fibrillary acidic protein) is generally seen as a key marker for identifying them.
  • The study used immunohistochemical methods to analyze brain biopsy samples from patients with various neurological conditions, noting that GFAP-positive fibrous astrocytes were primarily in specific brain regions, while protoplasmic astrocytes were rare.
  • The findings suggest that brain tissue contains GFAP-negative precursor cells that can become GFAP-positive under certain conditions, challenging current methods of identifying and classifying astrocytes in the adult brain.
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Lung contusion complicated by pneumonia worsens lung injury via the inflammatory effect of alveolar small extracellular vesicles on macrophages and epithelial cells.

J Trauma Acute Care Surg

January 2025

From the Division of Trauma, Surgical Critical Care, Burns and Acute Care Surgery, Department of Surgery (K.N., W.C., W.J., K.P., D.P., J.W., B.E., T.C.), UC San Diego School of Medicine, San Diego; Comparative Effectiveness and Clinical Outcomes Research Center (R.C.), Riverside University Health System, Loma Linda University School of Medicine, Riverside, California; and Trauma and Acute Critical Care Center (K.N.), Tokyo Medical and Dental University Hospital, Bunkyo-ku, Tokyo, Japan.

Article Synopsis
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There are few reports on long-term treatment of bovine osteomyelitis. In this study, two cattle (Japanese black heifer and calf) suffered damage to the dorsal metatarsal below the tarsus due to their hind limbs becoming caught in a metal fence, with consequent struggling and thrashing, causing osteomyelitis of the metatarsal. We present these two cases of osteomyelitis of the metatarsal and compare their: clinical conditions, effects of long-term treatment, and clinical outcomes.

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Article Synopsis
  • * The researchers created a new slow-release nanoparticle system (SNP-E2) for targeted delivery of E2 to the damaged spinal cord, avoiding systemic side effects, and demonstrating better sustained release compared to previous methods.
  • * The SNP-E2 treatment showed promising results in lab rats, including reduced inflammation, improved myelination, enhanced survival of brain cells, and better bladder and movement functions, indicating a possible effective therapy for SCI patients.
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Ethnopharmacological Relevance: Fritillaria imperialis L. (Fabaceae), commonly known as "Laleh vazhgon", ethnomedicinally utilized in Iranian traditional medicine to treat joint pain, chronic daily headaches, and back pain.

Aim Of The Study: To investigate the antinociceptive, anti-neuropathic, and anti-migraine activities of Fritillaria imperialis bulbs essential oil (FIEO) as well as to uncover the potential mechanisms of action involved.

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Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury.

Neural Regen Res

October 2025

Department of Spine Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, China.

JOURNAL/nrgr/04.03/01300535-202510000-00026/figure1/v/2024-11-26T163120Z/r/image-tiff Microglia, the resident monocyte of the central nervous system, play a crucial role in the response to spinal cord injury. However, the precise mechanism remains unclear.

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Characterization of Contusive Spinal Cord Injury by Monitoring Motor-Evoked Potential.

Biomedicines

November 2024

Department of Electrical Engineering, College of Engineering, American University of Sharjah, Sharjah P.O. Box 26666, United Arab Emirates.

Unlabelled: This study involves longitudinal neuro-electrophysiological analysis using motor-evoked potentials (MEP) and the Basso, Beattie, and Bresnahan behavioral examinations (BBB) to evaluate moderate mid-thoracic contusive spinal cord injury (SCI) in a rat model.

Objectives/background: The objective of the study is to characterize the onset and progression of contusive SCI over an eight-week period using a clinically applicable tool in an in vivo model. The background highlights the importance of a reliable and reproducible injury model and assessment tools for SCI.

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Sports training improves motor function after spinal cord injury by regulating microtubule dynamics.

Biochim Biophys Acta Mol Basis Dis

November 2024

Department of Rehabilitation Medicine, Peking University Third Hospital, 49 North Garden Road, Beijing 100191, China. Electronic address:

Spinal cord injury (SCI) often results in persistent disabilities, primarily due to deficient axon regeneration and irreversible neuronal loss. Sports training is a widely adopted intervention in clinical practice and research to promote axonal sprouting and synaptic plasticity, thereby improving motor function after SCI. However, the precise mechanisms by which sports training improves motor function after SCI remain incompletely understood.

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Introduction: Traumatic brain injury (TBI) is a leading cause of disability and mortality worldwide, with epidural hematoma (EDH) being a severe consequence. This study focuses on identifying factors predicting EDH volume changes in TBI patients and developing a machine learning (ML) model to predict EDH expansion.

Methods: The study includes patients with traumatic EDH between 2019 and 2021.

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