Neural modeling in electrical stimulation.

In general, complete mathematical modeling of electrical neurostimulation encompasses two separate problems; clear delineation of this article becomes important. Solutions are required for the time-varying macroscopic fields generated by the stimulating electrodes, and only then can biophysical analysis be brought to bear on neural structures within those fields. This article is focused on the second of these aspects, and provides a survey of mathematical representations including nerve cell bodies, myelinated and unmyelinated fibers of passage, branched systems, fiber terminals and composite neurons.