842 results match your criteria: "Contact Stomatitis"
[Lupus Cheilitis: a clinical case report].
Rev Med Inst Mex Seguro Soc
July 2024
Secretaría de Salud, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán", Departamento de Dermatología. Ciudad de México, México.
Background: Generalized lupus erythematosus (LEG) is an autoimmune disease with cutaneous and mucosal manifestations, with lupus cheilitis (LC) being a rare associated oral presentation. The difficulty in early diagnosis of QL lies in its various clinical forms. Although successful treatments have been described, information on specific management is limited, highlighting the importance of early recognition to improve the prognosis and quality of life of patients.
View Article and Find Full Text PDFAllergic contact cheilitis/stomatitis due to beverages and food, an underreported diagnosis.
Contact Dermatitis
November 2024
Faculty of Medicine, KU Leuven, Leuven, Belgium.
Enhancing antifungal and antibacterial properties of denture resins with nystatin-coated silver nanoparticles.
Sci Rep
October 2024
Department of Prosthodontics, Faculty of Dentistry, Tabriz University of Medical Sciences, Tabriz, Iran.
Article Synopsis
- Long-term oral health issues like denture stomatitis, mainly caused by the fungus C. albicans, are a concern for denture wearers, prompting research into more effective materials for denture construction.
- This study focuses on the antifungal and antibacterial properties of nystatin-coated silver nanoparticles (Nys-coated AgNPs) embedded in acrylic resin, demonstrating their effectiveness against C. albicans and Streptococcus mutans without toxic effects on healthy cells.
- Results indicate that Nys-coated AgNPs (specifically at a concentration of 10% w/w) significantly inhibited C. albicans growth and showed notable antibacterial activity, highlighting their potential as a better biocompatible material for denture resins.
Vesicular Stomatitis Virus Detected in Biting Midges and Black Flies during the 2023 Outbreak in Southern California.
Viruses
September 2024
Foreign Arthropod-Borne Animal Diseases Research Unit, National Bio- and Agro-Defense Facility, Agricultural Research Service, United States Department of Agriculture, Manhattan, KS 66502, USA.
Vesicular stomatitis (VS) is a viral disease that affects horses, cattle, and swine that is transmitted by direct contact and hematophagous insects. In 2023, a multi-state outbreak of vesicular stomatitis New Jersey virus (VSNJV) occurred in California, Nevada, and Texas, infecting horses, cattle, and rhinoceros. To identify possible insect vectors, we conducted insect surveillance at various locations in San Diego County, CA, including at a wildlife park.
View Article and Find Full Text PDFAntimicrobial hard denture reliners using quaternary ammonium methacryloxy silicate (K18 QAMS) and K18-functionalized filler.
J Appl Biomater Funct Mater
September 2024
Department of Comprehensive Dentistry, The University of Texas Health Science Center at San Antonio, San Antonio, TX, USA.
Objective: To determine the effects of adding a quaternary ammonium methacryloxy silicate (K18) and K18-functionalized filler (K18-Filler) on the material and antimicrobial properties of a hard denture reline material.
Materials And Methods: 30% K18 in methyl methacrylate (K18-MMA; 0-20 wt% of reliner) and K18-Filler (0-30 wt% of reliner) were incorporated into Kooliner hard denture reliner. Kooliner served as the control.
In situ gel-forming oil solubilizing α-lipoic acid as a physical shielding alleviated chemotherapy-induced oral mucositis via inhibiting oxidative stress.
Int J Pharm
November 2024
Department of Pharmaceutics, Key Laboratory of Novel Nuclide Technologies on Precision Diagnosis and Treatment & Clinical Transformation of Wenzhou City, School of Pharmaceutical Sciences, Wenzhou Medical University, Wenzhou City, Zhejiang Province 325035, China. Electronic address:
Article Synopsis
- Oral mucositis (OM) is a serious side effect of cancer treatment, and existing management techniques offer limited healing.
- A new in situ gel-forming oil (LGF) has been developed to provide better treatment, featuring good adhesion and wetting properties on oral tissues, which helps it stay in place.
- The oil contains α-lipoic acid, which gradually releases to reduce oxidative stress, promotes healing in animal studies, and reduces harmful inflammation associated with OM.
Synthesis and biological applications of nanocomposite hydrogels based on the methacrylation of hydroxypropyl methylcellulose and lignin loaded with alpha-pinene.
Carbohydr Polym
December 2024
Department of Materials Engineering, Isfahan University of Technology, 84156-83111 Isfahan, Iran.
Article Synopsis
- Oral conditions like recurrent aphthous stomatitis can greatly impact quality of life, prompting research into new treatment methods.
- This study develops a novel buccal mucoadhesive hydrogel using methacrylate hydroxypropyl methylcellulose and methacrylate lignin, combined with nanostructured lipid carriers to control the release of a compound called alpha-pinene.
- The resulting nanocomposite hydrogel showed improved mechanical strength, reduced energy loss during compression, controlled release of alpha-pinene over 96 hours, and enhanced adhesive properties, indicating potential for effective treatment in oral health applications.
Antifungal Effect of Poly(methyl methacrylate) with Farnesol and Undecylenic Acid against Biofilm Formation.
Materials (Basel)
August 2024
Powder Technology Laboratory, Institute of Materials, Ecole Polytechnique Fédérale de Lausanne, 1015 Lausanne, Switzerland.
Article Synopsis
- Controlling biofilm formation on dentures made from PMMA is crucial due to the biofilm's resistance to antifungal drugs.
- The study explores the combination of two natural compounds, undecylenic acid (UDA) and farnesol (FAR), which may work together synergistically to prevent biofilm formation on PMMA.
- The modified PMMA composites showed a decrease in biofilm and planktonic cell metabolic activity, indicating that UDA and FAR could be effective in reducing biofilm growth on dentures.
The outcomes of corneal sight rehabilitating surgery in Stevens-Johnson syndrome: case series.
BMC Ophthalmol
May 2024
Department of Ophthalmology, Peking University Third Hospital, Beijing, China.
Article Synopsis
- The study evaluated the effectiveness of corneal sight rehabilitation surgery in patients with Stevens-Johnson syndrome (SJS) by analyzing data from 24 eyes of 18 patients over a mean follow-up of 50.6 months.
- A total of 29 surgeries, including various combinations of keratoplasty and keratolimbal allografts, resulted in significant improvement in visual acuity, with 57.1% of patients no longer classified as having low vision and 88.9% no longer blind.
- Despite some complications like delayed epithelialization and glaucoma, the overall success rate of the procedures was high at 86.7%, demonstrating they can significantly enhance vision for SJS patients.
A case of severe benzalkonium chloride intoxication in a cat.
Acta Vet Scand
April 2024
Department of Life Sciences and Biotechnology, Faculty of Medicine, Pharmacy and Prevention, University of Ferrara, Via Luigi Borsari 46, 44121, Ferrara, Italy.
Article Synopsis
- * A case study of a 4-month-old kitten revealed severe health issues, including oral burns and lameness, after exposure to a 5% BAC-containing mold remover, necessitating hospitalization and supportive care.
- * The findings underscore the dangers of BAC for cats, emphasizing the need for increased awareness of its potential hazards in both home and professional environments, especially since this is one of the first reported cases in Italy.
Strategies for Preventing and Treating Oral Mucosal Infections Associated with Removable Dentures: A Scoping Review.
Antibiotics (Basel)
March 2024
Department of Dental Materials and Prosthesis, Ribeirão Preto School of Dentistry, University of São Paulo, Café Avenue S/N, Ribeirão Preto 14040-904, SP, Brazil.
Article Synopsis
- Oral infections linked to dentures arise from biofilms on denture surfaces contacting mucosal tissues, prompting a study on prevention and treatment strategies.
- The research involved analyzing 935 articles from various databases, narrowing it down to 104 relevant studies that fit their criteria, including 38 additional articles from gray literature.
- Key findings highlighted increased interest in antimicrobial solutions integrated into dentures and improved hygiene practices, particularly noting the effectiveness of brushing with sodium hypochlorite and promising new disinfectants.
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens.
Nat Microbiol
April 2024
Institute of Molecular Virology, Ulm University Medical Center, Ulm, Germany.
Article Synopsis
- - Some viruses, despite being present in saliva and semen, are not mainly transmitted through oral or sexual routes due to the presence of extracellular vesicles (EVs) in these fluids, which can inhibit viral infections.
- - The study found that these EVs expose a molecule called phosphatidylserine (PS), which plays a crucial role in preventing viruses like Zika from attaching and entering cells by blocking specific receptors they normally use.
- - While EVs effectively combat a variety of viruses through this mechanism, they do not interfere with certain other viruses like HIV or SARS-CoV-2, explaining why the transmission of these viruses often occurs through different pathways rather than direct human contact.
Contact allergies to dental materials in patients.
Br J Dermatol
May 2024
Department of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany.
Article Synopsis
- Concerns about allergic reactions to dental materials are increasing among patients, prompting a need to analyze current sensitization patterns.
- A study of 2730 patients revealed that women, particularly those over 40, showed the highest sensitization rates to metals like nickel and palladium, as well as to (meth)acrylates.
- The findings suggest that patch testing for contact allergies should also include (meth)acrylates and natural substances like propolis, rather than focusing solely on metals.
Strategic combination of cultivated oral mucosal epithelial transplantation and postoperative limbal-rigid contact lens-wear for end-stage ocular surface disease: a retrospective cohort study.
Br J Ophthalmol
July 2024
Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan
Article Synopsis
- The study aimed to evaluate the long-term outcomes of cultivated oral mucosal epithelial transplantation (COMET) combined with limbal-rigid contact lens therapy in patients with severe ocular surface disease (OSD).
- Researchers reviewed data from 18 patients over a period from 2002 to 2019, focusing on factors like best-corrected visual acuity (BCVA) and Ocular Surface Grading Scores (OSGS) before and after treatment.
- Results showed a significant improvement in vision and ocular surface conditions with no major complications, confirming the effectiveness of this combined treatment for improving quality of life in these patients.
Oral lichenoid lesions in two snuff users with contact allergy to carvone.
Contact Dermatitis
January 2024
Department of Occupational and Environmental Dermatology, Skåne University Hospital, Malmo, Sweden.
Article Synopsis
- A study was conducted to examine if mint-flavoured snuff is linked to contact allergy from carvone, which has been noted in patients with oral lichenoid lesions (OLL).
- Two patients with OLL were found to be allergic to carvone through patch testing, and they had been using mint-flavoured snuff for years; carvone was also detected in their snuff samples.
- After being advised to stop using mint-flavoured products, the patients showed significant improvement in their oral symptoms within three months, suggesting that mint-flavouring can worsen OLL.
Recurrent allergic contact stomatitis and aphtosis, without cheilitis, due to stannous (tin)-containing toothpastes.
Contact Dermatitis
December 2023
Department of Dermatology, University Hospital Antwerp (UZA) and Research group Immunology, University of Antwerp, Antwerp, Belgium.
Allergic Contact Stomatitis Caused by (Meth)acrylates in a Gingival Protection Product Used During Teeth Whitening.
Dermatitis
January 2024
From the Department of Dermatology, Tokyo Dental College, Ichikawa General Hospital, Ichikawa, Japan.
Storage-related stability and antimicrobial efficacy of bottled, neutral-pH Electrolysed Oxidising Water.
J Dent
October 2023
Sir John Walsh Research Institute, Faculty of Dentistry, University of Otago, Dunedin, New Zealand. Electronic address:
Article Synopsis
- Denture stomatitis is common in older adults, posing health risks, and this study evaluates the effectiveness of ready-to-use neutral-pH Electrolysed Oxidizing Water (EOW) as a disinfectant for dentures, particularly against Candida albicans biofilms.
- The research involved measuring various properties of EOW over time and testing its antimicrobial activity, showing that EOW maintains its effectiveness even after five months of storage at cool or room temperatures.
- Results indicated that EOW significantly reduces bacterial and fungal colonies and biofilm activity, supporting its use for denture disinfection in clinical settings.
Triamcinolone acetonide release modelling from novel bilayer mucoadhesive films: an in vitro study.
Dent Mater
June 2023
Dental Physical Science Unit, Faculty of Medicine and Dentistry, Queen Mary University of London, Mile End Road, London E1 4NS, UK.
Objectives: Recurrent aphthous stomatitis (RAS) is a painful disorder that commonly appears as ulcers on the oral mucosa, lasting ∼two weeks (minor) to months (major and herpetiform). Current treatment often necessitates the use of topical steroids in the form of pastes, mouthwashes, or gels, but these forms are often ineffective due to inadequate drug contact time with the ulcers. In this study, the performance of novel bilayer mucoadhesive buccal films loaded with triamcinolone acetonide (TA) has been evaluated for targeted drug delivery.
View Article and Find Full Text PDFVitamin B group levels and supplementations in dermatology.
Dermatol Reports
March 2023
Reader in clinical pharmacy, University of Wolverhampton, School of Pharmacy, United Kingdom.
Article Synopsis
- Irregular vitamin levels are linked to various skin conditions, with therapies showing some positive effects; however, outcomes can vary widely, indicating that these issues aren't just due to one nutrient deficiency.
- Certain B vitamins, particularly cyanocobalamin, B6, and B2, may actually worsen acne and cause allergic reactions in some patients, sometimes leading to severe skin issues.
- Niacinamide is emerging as a beneficial treatment for acne and hyperpigmentation and shows potential in preventing nonmelanoma skin cancers, while the role of folic acid in psoriasis is developing and the data for vitiligo is still unclear; vitamin deficiency checks should be routine in skin condition assessments.
Long-Term Benefits of Tear Exchangeable Limbal-Rigid Contact Lens Wear Therapy in Stevens-Johnson Syndrome Cases.
Eye Contact Lens
June 2023
Department of Ophthalmology (Y.Y., T.K), Osaka Medical and Pharmaceutical University, Takatsuki-City, Osaka; Department of Ophthalmology (Y.Y., C.S.), Kyoto Prefectural University of Medicine, Kyoto; and Department of Frontier Medical Science and Technology for Ophthalmology (U.M., S.K.), Kyoto Prefectural University of Medicine, Kyoto, Japan.
Article Synopsis
- The study investigates the long-term effectiveness of limbal-rigid contact lenses on patients with ocular issues from Stevens-Johnson syndrome (SJS).
- It involved 50 eyes of 41 patients and assessed eye conditions and visual acuity over an average of 4.3 years after the lenses were fitted.
- Results showed significant improvements in conjunctival hyperemia and corneal neovascularization scores, as well as a notable enhancement in visual acuity, suggesting that this lens therapy aids in stabilizing the eye surface for SJS patients.
Acute Immune-Mediated Lesions of the Oral Cavity.
Oral Maxillofac Surg Clin North Am
May 2023
WesternU Health Oral Pathology, 701 East 2nd Street, Room 3204, Pomona, CA 91766, USA.
Article Synopsis
- Acute immune-mediated lesions of the oral cavity (AIML) can develop gradually but often present quickly and may resolve on their own.
- Even though some disorders may be self-limiting, they can cause considerable pain and affect multiple body systems.
- Accurate diagnosis by oral health care providers is crucial to differentiate AIML from similar conditions, as the oral symptoms might indicate more serious underlying systemic issues.
Antifungal efficiency and cytocompatibility of polymethyl methacrylate modified with zinc dimethacrylate.
Front Cell Infect Microbiol
April 2023
Dental Medical Center, China-Japan Friendship Hospital, Beijing, China.
Article Synopsis
- The study aimed to examine how modifying polymethyl methacrylate (PMMA) denture base resin with zinc dimethacrylate (ZDMA) affects its antifungal properties and cytotoxicity, addressing the common issue of denture stomatitis.
- Various concentrations of ZDMA were tested against unmodified PMMA using different scientific analyses, such as FTIR and thermogravimetric analysis, to assess changes in thermal stability, surface characteristics, and biological effects.
- Results showed that ZDMA enhanced PMMA's antifungal activity and thermal stability, improved hydrophilicity, and increased surface roughness without compromising cytocompatibility significantly.
Molecular Tracking of the Origin of Vesicular Stomatitis Outbreaks in 2004 and 2018, Ecuador.
Vet Sci
February 2023
One Health Research Group, Facultad de Ciencias Veterinarias, Universidad de Las Américas, Quito 170530, Ecuador.
Article Synopsis
- The Vesicular Stomatitis Virus (VSV) is an arbovirus that affects livestock, with two recognized serotypes: New Jersey and Indiana, which can be transmitted through contact or vectors.
- In 2018, Ecuador faced an outbreak of VSV, resulting in 399 reported cases across 18 provinces, linked to both serotypes VSNJV and VSIV.
- Phylogenetic analyses indicated two separate origins for the outbreaks in 2004 and 2018, highlighting distinct transmission patterns, and suggesting a need for further research on vectors and reservoirs in Ecuador to understand the virus's resurgence.