160 results match your criteria: "Consultant in Special Care Dentistry at King´s College Hospital[Affiliation]"
Do We Have Sufficient Evidence to Derive Innovative Approaches to Assessing Unmet Need, Delivering Education on Bladder and Bowel Continence Health, and Providing a Better Environment for Joint Decision-Making? ICI-RS 2024.
Neurourol Urodyn
January 2025
Department of Medicine, College of Health Sciences, Faculty of Medicine & Dentistry, Division of Geriatric Medicine, Edmonton, Alberta, Canada.
Context: Improved continence outcomes are reliant on identification of unmet need, education delivery, and shared decision-making. The evidence base on which to derive innovative approaches in these areas was unclear.
Methods: A debate held at the International Consultation on Incontinence-Research Society meeting, held in Bristol in June 2024, considered ways to improve research requirements to advance these areas.
Disparities in kidney care in vulnerable populations: A multinational study from the ISN-GKHA.
PLOS Glob Public Health
December 2024
Centre for Kidney Disease Research, University of Queensland, Brisbane, Queensland, Australia.
Vulnerable populations, such as the elderly, children, displaced people, and refugees, often encounter challenges in accessing healthcare. In this study, we used data from the third iteration of the International Society of Nephrology Global Kidney Health Atlas (ISN-GKHA) to describe kidney care access and delivery to vulnerable populations across countries and regions. Using data from an international survey of clinicians, policymakers, and patient advocates, we assessed the funding and coverage of vulnerable populations on all aspects of kidney replacement therapies (KRT).
View Article and Find Full Text PDFThe COnfederation of REspiratory Critical Care Trials (CoReCCT): a UK research confederation.
Br J Anaesth
February 2025
School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast, UK.
Article Synopsis
- The text discusses the importance of forecasting future health issues in the USA for effective planning and public awareness regarding disease and injury burdens.
- It describes the methodology for predicting life expectancy, cause-specific mortality, and disability-adjusted life-years (DALYs) from 2022 to 2050 using the Global Burden of Diseases framework.
- The forecasting includes various scenarios to assess the potential impacts of health risks and improvements across the country, focusing on demographic trends and health-related risk factors.
APASL clinical practice guidelines on systemic therapy for hepatocellular carcinoma-2024.
Hepatol Int
December 2024
Department of Gastroenterology, Yamanashi Prefectural Center Hospital, Kofu-City, Yamanashi, Japan.
Article Synopsis
- * Recent advancements in targeted therapy and immune-checkpoint inhibitors are now becoming available for treating unresectable HCC and preventing recurrence after curative procedures.
- * This clinical practice guideline aims to provide updated recommendations from Asia-Pacific experts on systemic therapy for HCC, addressing key questions about patient selection, effective treatments, and management strategies for immunotherapy.
Article Synopsis
- Chronic cough is a common medical issue that affects patients' quality of life but is often poorly managed due to reliance on outdated treatment methods and lengthy waiting times for care.
- Current approaches treat chronic cough as a symptom of other conditions, leading to unnecessary costs and potential harm, rather than recognizing it as a distinct disease.
- Newer guidelines suggest that chronic cough should be viewed as its own condition, which could improve patient understanding, treatment focus, healthcare organization, and research advancements.
A randomized controlled trial of an online support group addressing psychosexual distress among women treated for gynecologic cancer.
Gynecol Oncol
January 2025
Department of Obstetrics and Gynecology, Temerty School of Medicine, University of Toronto, Toronto, Ontario, Canada; Division of Gynecologic Oncology Princess Margaret Cancer Centre, University Health Network/Sinai Health System, Toronto, Ontario, Canada. Electronic address:
Objective: To assess whether a 12-week, professionally facilitated, asynchronous online support group would reduce sexual distress (primary outcome) and improve sexual function, body image, depression symptoms, relationship satisfaction, and social support (secondary outcomes) in women treated for gynecologic cancer.
Methods: Participants were 398 women recruited from three Canadian provinces and one American cancer center in cohorts of 40. Participants were randomized (50:50 odds) to either the immediate treatment condition (ITC) or the waitlist control condition (WCC).
Patient-centred composite scores as tools for assesment of response to biological therapy for paediatric and adult severe asthma.
Eur Respir J
November 2024
Clinical and Experimental Sciences and Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.
Article Synopsis
- - The development of the CompOsite iNdexes For Response in asthMa (CONFiRM) aimed to create patient-centered tools that measure responses to biologics for severe asthma in both adults and children, integrating clinical data and quality of life (QoL) indicators.
- - Experts and patients collaborated to identify significant outcome changes and devised CONFiRM scores, which demonstrated high levels of agreement on key factors, with patients emphasizing the importance of quality of life more than healthcare professionals did.
- - The CONFiRM scores effectively measure treatment response, with strong validity metrics indicating their reliability, and they facilitate a comprehensive assessment of biologics’ effectiveness; further studies are required for prospective validation.
Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records.
Lancet Public Health
November 2024
British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK; National Institute for Health Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK; Health Data Research UK Cambridge, Wellcome Genome Campus, University of Cambridge, Cambridge, UK; Cambridge Centre for Artificial Intelligence in Medicine, University of Cambridge, Cambridge, UK; British Heart Foundation Data Science Centre, London, UK. Electronic address:
Background: Heart failure is common, complex, and often associated with coexisting chronic medical conditions and a high mortality. We aimed to assess the epidemiology of people admitted to hospital with heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF), including the period covering the COVID-19 pandemic, which was previously not well characterised.
Methods: In this retrospective, cohort study, we used whole-population electronic health records with 57 million individuals in England to identify patients hospitalised with heart failure as the primary diagnosis in any consultant episode of an in-patient admission to a National Health Service (NHS) hospital.
Article Synopsis
- The study analyzed global, regional, and national trends in injury burden and identified risk factors contributing to injuries using data from the GBD 2019.
- In 2019, there were approximately 713.9 million injury incidents and 4.3 million injury-related deaths globally, with low bone mineral density emerging as the leading risk factor.
- The findings emphasize the need for effective global injury prevention policies by highlighting the persistent impact of injuries on global health.
Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study.
Int J Epidemiol
February 2024
The Institute for Lung Health, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.
Article Synopsis
- * Recent efforts to stop smoking haven't been put into action yet, and it’s important to see what could happen if smoking rates stay the same or improve.
- * Researchers used models to predict health outcomes by 2050 based on different scenarios of smoking rates, showing that cutting smoking could greatly improve health and life expectancy.
Article Synopsis
- Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
- In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
- There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
Temporal Trends in Takotsubo Syndrome: Results From the International Takotsubo Registry.
J Am Coll Cardiol
September 2024
Department of Cardiology and Internal Medicine B, University Medicine Greifswald, Greifswald, Germany; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany; First Clinic of Internal Medicine, Department of Internal Medicine, University of Genoa, Genoa, Italy.
Article Synopsis
- The study investigated changes in demographics, risk factors, clinical presentations, and outcomes of takotsubo syndrome (TTS) patients from 2004 to 2021, using data from the InterTAK registry.
- Over the years, the proportion of male patients increased, and there was a rise in cases of midventricular TTS as well as significant growth in the incidence of physical triggers.
- There was also a notable increase in 60-day mortality rates, although no significant change in 1-year mortality when excluding early deaths was observed, indicating a complex evolution of TTS and its management in recent years.
MAPT H2 haplotype and risk of Pick's disease in the Pick's disease International Consortium: a genetic association study.
Lancet Neurol
May 2024
Department of Neuroscience, Mayo Clinic, Jacksonville, FL, USA; Department of Clinical Genomics, Mayo Clinic, Jacksonville, FL, USA. Electronic address:
Article Synopsis
- Pick's disease is a rare form of frontotemporal dementia characterized by Pick bodies in the brain, which are linked to the MAPT gene and its haplotypes, H1 and H2.
- The study aimed to investigate how the MAPT H2 haplotype influences the risk, age of onset, and duration of Pick's disease.
- Data was collected from 338 individuals with confirmed Pick's disease across multiple sites, and associations of MAPT variants with the disease were analyzed using statistical models.
Clinical, experimental and pathophysiological effects of Yaq-001: a non-absorbable, gut-restricted adsorbent in models and patients with cirrhosis.
Gut
June 2024
Liver Failure Group, UCL Institute for Liver & Digestive Health, Division of Medicine, London, UK
Objective: Targeting bacterial translocation in cirrhosis is limited to antibiotics with risk of antimicrobial resistance. This study explored the therapeutic potential of a non-absorbable, gut-restricted, engineered carbon bead adsorbent, Yaq-001 in models of cirrhosis and acute-on-chronic liver failure (ACLF) and, its safety and tolerability in a clinical trial in cirrhosis.
Design: Performance of Yaq-001 was evaluated .
Collating the voice of people with autoimmune diseases: Methodology for the Third Phase of the COVAD Studies.
Rheumatol Int
July 2024
Division of Musculoskeletal and Dermatological Sciences, Centre for Musculoskeletal Research, School of Biological Sciences, The University of Manchester, Manchester, UK.
Article Synopsis
- The focus on holistic patient care for autoimmune and rheumatic diseases (AIRDs) emphasizes the importance of subjective well-being, social factors, and mental health, alongside traditional measures of disease.
- The COVAD-3 survey is set up as an extensive online self-report study to assess various lifestyle factors of AIRD patients and healthy individuals, ensuring it's accessible through multiple languages and thorough testing.
- The goal of COVAD-3 is to understand how social, economic, and psychological factors affect the quality of life in AIRD patients, ultimately aiming to enhance their overall health and treatment approaches.
Exploring Artificial Intelligence and the Future of Primary Care.
Ann Fam Med
March 2024
Department of Health Systems and Population Health Sciences, University of Houston Tilman J. Fertitta Family College of Medicine, Houston, TX.
Reporting of equity in observational epidemiology: A methodological review.
J Glob Health
March 2024
Bruyère Research Institute, University of Ottawa, Ottawa, Ontario, Canada.
Article Synopsis
- Observational studies are essential for understanding health inequities, but it's unclear how well they report equity-related factors in their design and analysis.
- The authors reviewed 16,828 articles from 2020 to 2022, selecting 320 studies to analyze their focus on populations facing inequities and data collection methods.
- Findings showed that while many studies acknowledged health equity, only a small percentage effectively reported key design aspects related to equity, indicating a significant gap in the methodology of health equity research.