1,460 results match your criteria: "Congenital Cystic Adenomatoid Malformation"

Thoracoscopic anatomical lesion resection by fluorescence imaging on congenital lung malformation.

Asian J Surg

November 2024

Department of Pediatric Surgery, West China Hospital of Sichuan University, NO. 37 GUOXUE Lane, Chengdu, 610041, Sichuan Province, China. Electronic address:

Article Synopsis
View Article and Find Full Text PDF

Congenital pulmonary airway malformation in a cat.

J Vet Diagn Invest

October 2024

Oregon Veterinary Diagnostic Laboratory, Oregon State University, Corvallis, OR, USA.

Congenital structural anomalies of the lower airways of the respiratory tract are uncommon in cats. We describe here a case of cystic pulmonary lesions in a 6-wk-old domestic shorthair cat consistent with congenital pulmonary airway malformation (CPAM; formerly referred to as cystic adenomatoid malformation of the lung, or congenital pulmonary adenomatoid malformation; Stocker type II). CPAM is rarely reported in veterinary species and, to our knowledge, has not been reported in cats.

View Article and Find Full Text PDF

Objective: To study the clinical and morphological manifestations of lung sequestration.

Material And Methods: Surgical material (lung tissue) of 18 patients (2017-2021) and 8 archival observations (1972-1994) of confirmed lung sequestration were examined. Histological staining (hematoxylin and eosin, Schiff reagent, Ziehl-Neelsen, picrofuchsin according to Van Gieson) and immunohistochemical reactions with antibodies to SMA, TTF1, CK5/6 (DAKO) were performed.

View Article and Find Full Text PDF

Background: There is limited literature on optimal timing for elective thoracoscopic lobectomy for congenital pulmonary airway malformations (CPAM) and sequestration. Using NSQIP-P, we aim to assess optimal operative timing for elective thoracoscopic lobectomy for CPAM and sequestration.

Methods: Data from the NSQIP-Pediatric registry was used to evaluate elective thoracoscopic lobectomy patients from 2017 to 2021 diagnosed with congenital pulmonary airway malformation or sequestration.

View Article and Find Full Text PDF

Congenital cystic adenomatoid malformation in a toddler: Unusual presentation with pleural effusion.

Radiol Case Rep

November 2024

Pediatric A Department, Mohammed VI University Hospital, Marrakesh, Morocco, Faculty of Medicine and Pharmacy, University Cadi Ayyad, Morocco.

Congenital cystic adenomatoid malformation encompasses a series of cystic malformative lesions characterized by aberrant bronchiolar formations of varying size and dispersion. Most cases of this illness are detected in the first few years of life, usually affecting infants. We report a case of CCAM presenting as pleural effusion in a 15-month-old boy who presented with acute respiratory distress.

View Article and Find Full Text PDF

Lung-protective ventilation and postoperative pulmonary complications during pulmonary resection in children: A prospective, single-centre, randomised controlled trial.

Eur J Anaesthesiol

December 2024

From the Department of Anesthesiology, Shanghai Children's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (CZ, SZ, RW), Department of Anesthesiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China (CZ, MZ), Cardiothoracic Surgery Department, Shanghai Children's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China (RZ).

Article Synopsis
View Article and Find Full Text PDF
Article Synopsis
  • - The study investigates the link between congenital lung malformations (CLMs) and the risk of developing cancer by examining genetic mutations in various lung malformations through whole-genome sequencing.
  • - Analysis revealed that 95% of the CLMs exhibited genomic instability, with 30% harboring genetic variants associated with tumor development, suggesting a potential predisposition to malignancy.
  • - The findings indicate that while CLMs are often benign, their genetic alterations, combined with environmental carcinogenic factors, may increase the likelihood of lung cancer, highlighting a significant biological connection.
View Article and Find Full Text PDF

Objective: To investigate the value of magnetic resonance examination technique for prenatal genetic diagnosis and clinical intrauterine treatment of fetal congenital cystic adenoma (CCAM) of the lung.

Methods: A retrospective analysis was conducted on 108 pregnant women admitted to a certain hospital from January 2016 to January 2022 for pre natal examination and consultation on eugenics. The selected pregnant women were aged 20-40 and had a gestational age of 17-36 weeks.

View Article and Find Full Text PDF

Coexisting congenital cystic adenomatous malformation of the lungs and severe pectus excavatum (PE) is an uncommon presentation that poses significant management challenges. Conventionally managed in a staged manner, there are increasing reports of superior outcomes with single-staged concurrent repair with minimally invasive techniques (video-assisted thoracoscopic surgery [VATS] and minimally invasive repair of PE [MIRPE]). The outcome of a single-stage open repair for both anomalies has not been previously reported to the best of our search.

View Article and Find Full Text PDF
Article Synopsis
  • Congenital lung anomalies (CLA) include various rare conditions like CCAM, BPS, CLE, and BC, which are now more commonly diagnosed thanks to better fetal ultrasound technology.
  • A study of 72 patients at Taleghani Pediatric Hospital revealed that most had CCAM, with a notable percentage showing respiratory symptoms; prenatal screenings were effective in diagnosing many cases.
  • The findings suggest a link between the type of lung anomaly and the need for surgical intervention, and highlight that improving diagnostic techniques may lead to better management of these anomalies.
View Article and Find Full Text PDF

[Application of Fetal Magnetic Resonance Imaging in Prognosis Assessment of Fetuses With Congenital Pulmonary Cystic Diseases].

Sichuan Da Xue Xue Bao Yi Xue Ban

May 2024

( 610041) Department of Radiology, West China Second University Hospital, Sichuan University, Chengdu 610041, China.

Article Synopsis
View Article and Find Full Text PDF

Congenital Chest Lesions and Interventions.

Magn Reson Imaging Clin N Am

August 2024

Department of Radiology and Imaging Sciences, Emory University, 1405 Clifton Road Northeast, Atlanta, GA 30322, USA. Electronic address:

Anomalies of the fetal chest require advanced imaging with ultrasound and MR imaging as well as expertise on the part of the interpreting pediatric radiologist. Congenital diaphragmatic hernia and congenital lung malformation are the most frequently seen, and in both conditions, the radiologist should provide both detailed anatomic description and measurement data for prognostication. This article provides a detailed approach to imaging the anatomy, in-depth explanation of available measurements and prognostic value, and keys to identifying candidates for fetal intervention.

View Article and Find Full Text PDF
Article Synopsis
  • The case involves a prenatal diagnosis of Bronchopulmonary Sequestration (BPS) associated with Congenital Pulmonary Airway Malformation (CPAM), identified through fetal 3D ultrasound (3D-US).
  • The diagnosis revealed an unusual configuration of two abnormal arteries originating from the celiac artery.
  • The vascular images captured via fetal 3D-US were found to be comparable to those acquired through postnatal CT angiography, indicating the potential efficacy of 3D-US in prenatal vascular assessments.
View Article and Find Full Text PDF

Background: Congenital pulmonary airway malformation (CPAM) is a rare benign deformity of the lungs in adults. Our study aimed to evaluate the clinical features and compare the effect of thoracoscopic lobectomy and wedge resection for adult CPAMs.

Methods: This was a retrospective study including eighteen adults with CPAMs recruited between 2013 and 2023.

View Article and Find Full Text PDF

Comparison of ICG-Guided Near-Infrared Fluorescence Imaging and Modified Inflation-Deflation Method in Identifying the Intersegmental Plane During Lung Segmentectomy of Infants.

J Pediatr Surg

September 2024

Department of Cardiothoracic Surgery, Fujian Children's Hospital (Fujian Branch of Shanghai Children's Medical Center), College of Clinical Medicine for Obstetrics & Gynecology and Pediatrics, Fujian Medical University, Fuzhou, China.

Article Synopsis
  • The study compared two methods for identifying the intersegmental plane (ISP) during segmentectomy for children with congenital pulmonary airway malformation (CPAM): the intravenous indocyanine green (ICG)-guided near-infrared fluorescence (NIRF) method and the modified inflation-deflation method.
  • Data from 83 patients were analyzed, showing that the ICG method significantly reduced the time needed to identify the ISP and overall surgical duration compared to the modified inflation-deflation method.
  • Although both methods had similar outcomes regarding chest tube drainage, hospital stay, blood loss, and postoperative complications, the ICG method proved to be quicker and equally safe, with patients recovering well beyond one year
View Article and Find Full Text PDF

Efficacy of Da Vinci Robot-assisted Thoracoscopic Surgery in Children With Congenital Cystic Adenomatiod Malformation.

J Pediatr Surg

August 2024

Department of Pediatric Surgery, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, China. Electronic address:

Article Synopsis
View Article and Find Full Text PDF

Antenatally Detected Thoracic Lesions: Prognosis, Management and Outcome.

Afr J Paediatr Surg

April 2024

Department of Pediatric Surgery, PGIMER, Chandigarh, India.

Background: Foetal thoracic lesions are uncommon, with the incidence of 1 in 15,000 live births. Antenatal monitoring of these lesions is required to prognosticate the parents about the postnatal outcome of the lesions and about the well-being of the baby. Foetal ultrasound and magnetic resonance imaging (MRI) are the modalities to detect these lesions and follow-up during pregnancy and postnatally.

View Article and Find Full Text PDF
Article Synopsis
  • * A 4-year-old girl with this condition experienced recurring chest infections, which prompted imaging that confirmed type I congenital pulmonary airway malformation associated with an infection.
  • * The patient underwent surgery to remove part of her lung and had a successful recovery, highlighting the need for more research on surgical outcomes for symptomatic patients compared to asymptomatic ones.
View Article and Find Full Text PDF

Congenital pulmonary airway malformations (CPAM) compose the major part of congenital lung malformations (CLM) and have traditionally been treated by pulmonary lobectomy. In terms of surgical strategy, lobectomy has conventionally been the preferred treatment for CPAM localized to a single lobe. More recently, alternative approaches including lung-sparing resections (LSR), such as wedge or non-anatomic resections and segmentectomy, have been suggested.

View Article and Find Full Text PDF
Article Synopsis
  • The study investigates the mediastinal shift angle as a new MRI index linked to survival rates in fetuses with congenital diaphragmatic hernia, but its relevance in congenital pulmonary airway malformation (CPAM) had not been explored.
  • Researchers measured the mediastinal shift angles in 124 control fetuses and 32 fetuses diagnosed with CPAM, finding significant differences and a positive correlation with the CPAM volume ratio.
  • Results suggest that the mediastinal shift angle might effectively assess CPAM severity in fetal MRI, showing promising accuracy for clinical use.
View Article and Find Full Text PDF

To investigate the clinicopathological features and genetic characteristics of congenital cystic adenomatoid malformation (CCAM) of lung and CCAM associated lung cancer in adults. A total of 13 cases of CCAM of lung in adults, diagnosed from June 2015 to May 2023, were collected from the Department of Pathology, Shanghai Pulmonary Hospital, Tongji University School of Medicine, China. Their histopathological features were correlated with probable development into lung cancer.

View Article and Find Full Text PDF