780 results match your criteria: "Comprehensive Health Research Centre [CHRC][Affiliation]"

Donkey endometrium: Characterization of resident immune cells.

Res Vet Sci

December 2024

Animal and Veterinary Research Center (CECAV), University of Trás-os-Montes e Alto Douro, Quinta de Prados, 500-801 Vila Real, Portugal; Associate Laboratory for Animal and Veterinary Sciences (AL4AnimalS), Portugal. Electronic address:

The Burro de Miranda is an endangered donkey breed. The dynamics of the immune system of the donkey's reproductive tract are essential to manage the fertility of these animals for the improvement and survival of the species. In mares, high numbers of immune cells infiltrating the endometrium promote endometrosis, which is still to be confirmed in jennies.

View Article and Find Full Text PDF

Exploring canine mast cell tumors: An investigation into demographic characteristics, and grading system analysis from a pathology lab data (2019-2021).

Prev Vet Med

January 2025

DNAtech, Laboratório Veterinário, Lisboa, Portugal; CECAV, Centro de Ciência Animal e Veterinária, Faculdade de Medicina Veterinária, Universidade Lusófona-Centro Universitário de Lisboa, Portugal; CBIOS - Centro de Investigação em Biociências e Tecnologias da Saúde - Universidade Lusófona, Lisboa, Portugal.

Mast cell tumors (MCT) are among the most common neoplasia in dogs, representing up to 21 % of skin tumors. However, etiology and risk factors for its development remain unclear. This study aimed to reduce this knowledge gap by comprehensively analyzing 905 MCT cases diagnosed in Portugal between 2019 and 2021, using descriptive and inferential analyses.

View Article and Find Full Text PDF

Evidence suggests that older adults who survived COVID-19 were exposed to greater functional dependence in their daily living activities. This study aims to examine the prevalence of functional dependence and associated factors among Brazilian older people with functional dependence 12 months after COVID-19 infection. A cross-sectional study was carried out involving people aged 60 years or older in the state of Paraná, Brazil.

View Article and Find Full Text PDF

Creatine monohydrate supplementation is widely used by athletes in high-intensity, power-based sports due to its ability to enhance short-term performance by increasing intramuscular phosphocreatine (PCr) stores, which aid in ATP resynthesis during intense muscle contractions. However, emerging evidence suggests that creatine monohydrate offers benefits beyond athletic performance. This narrative review explores the literature supporting the advantages of creatine supplementation in women, vegans, and clinical populations.

View Article and Find Full Text PDF

Early Mortality Prediction in Intensive Care Unit Patients Based on Serum Metabolomic Fingerprint.

Int J Mol Sci

December 2024

ISEL-Instituto Superior de Engenharia de Lisboa, Instituto Politécnico de Lisboa, Rua Conselheiro Emídio Navarro 1, 1959-007 Lisbon, Portugal.

Predicting mortality in intensive care units (ICUs) is essential for timely interventions and efficient resource use, especially during pandemics like COVID-19, where high mortality persisted even after the state of emergency ended. Current mortality prediction methods remain limited, especially for critically ill ICU patients, due to their dynamic metabolic changes and heterogeneous pathophysiological processes. This study evaluated how the serum metabolomic fingerprint, acquired through Fourier-Transform Infrared (FTIR) spectroscopy, could support mortality prediction models in COVID-19 ICU patients.

View Article and Find Full Text PDF

Laser-Based Length-Measuring Board for the Measurement of Infant Body Length from Outside an Incubator: Proposal and Assessment of a Model.

Children (Basel)

December 2024

Instituto de Plasmas e Fusão Nuclear, Instituto Superior Técnico, Universidade de Lisboa, 1049-001 Lisbon, Portugal.

Introduction: Opening the incubator side wall to insert a non-sterile length-measuring device carries the risk of microbial contamination and thermal instability for preterm infants. To reduce this inconvenience, a laser-based length-measuring board is proposed to measure body length from outside the incubator.

Methods: This device has two laser-line-shaped cursors which can be pointed to opposite ends of a segment to be measured.

View Article and Find Full Text PDF

Motor Competence in Autistic Children with Attention-Deficit Hyperactivity Disorder.

Children (Basel)

December 2024

CIPER, Faculdade de Motricidade Humana, Universidade de Lisboa, 1499-002 Cruz Quebrada-Dafundo, Portugal.

Background/objectives: Children with autism exhibit deficits in fundamental motor skills, which are intensified when associated with attention-deficit/hyperactivity disorder (ADHD).

Objective: To correlate motor competence in children with autism, autism levels according to the CARS scale, and the association with ADHD.

Methods: This cross-sectional study assessed motor competence using the Motor Competence Assessment (MCA), the severity of Autism Spectrum Disorder by Childhood Autism Rating Scale (CARS), and the presence of clinical signs for ADHD using Swanson, Nolan, and Pelham (SNAP-IV) questionnaire.

View Article and Find Full Text PDF

Unlabelled: The global ageing population faces rising depression rates due to social, economic, and health changes. Depression in older adults, often linked to isolation and health issues, requires comprehensive care. Psychotherapeutic interventions could be effective in reducing symptoms, offering personalized and holistic support.

View Article and Find Full Text PDF

Diabetes mellitus (DM) is one of the most common chronic endocrine diseases, characterized by hyperglycemia, due to abnormal nitric oxide synthesis. The trend of an increase in the number of patients with DM continues. The medical and economic burden of DM is not only associated with hyperglycemia management but also with the management of DM-related complications.

View Article and Find Full Text PDF

Objective: The objective of this review is to evaluate the effectiveness of interventions to prevent or treat prolonged grief symptoms among families of patients who die in intensive care units (ICU).

Introduction: Up to 52% of families of patients who die in ICU may be at risk of experiencing prolonged grief symptoms.

Inclusion Criteria: Studies of adult family members (≥18 years) of adult ICU patients (≥18 years) who underwent a treatment withdrawal or withholding decision, and who were exposed to tailored interventions to prevent or treat prolonged grief symptoms before, during, and/or after the patient's death will be considered for inclusion.

View Article and Find Full Text PDF

This study aimed to investigate the impact of different offensive-reward-related rules on the physical performance, perceived exertion and enjoyment of young basketball players during small-sided games (SSG). Eighteen youth male players (age: 13.3±0.

View Article and Find Full Text PDF

Equine endometrosis is a major cause of infertility in mares and is characterized by degenerative, functional and fibrotic changes in the endometrium with increased collagen (COL) deposition. Transforming growth factor (TGF)-β1 is one of the major pro-fibrotic factors involved in the excessive deposition of extracellular matrix (ECM) components in the equine endometrium. It has been demonstrated that ovarian steroids, specifically 17β-estradiol (E2) and progesterone (P4), not only regulate the cyclicity of the estrous cycle, but also have been implicated as anti- or pro-fibrotic factors.

View Article and Find Full Text PDF

Background: Lithuania ratified the UN Convention on the Rights of Persons with Disabilities (UNCRPD) in 2010 and started deinstitutionalisation in 2014. This reform covers segregated social care institutions where persons with mental health conditions, psychosocial and/or intellectual disabilities live. It aims to move away from institutional care and towards community-based services.

View Article and Find Full Text PDF

The time-course changes in postural control variability between neck pain and asymptomatic dental students.

Sci Rep

December 2024

Neuromuscular Research Lab, Interdisciplinary Centre for the study of Human Performance (CIPER), Faculty of Human Kinetics, University of Lisbon, 1499-002, Oeiras, Portugal.

Changes in postural control associated with clinical practice or specific conditions such as the presence of neck pain remain unexplored in dental students. Therefore, this study aimed to explore the time-course changes in postural control complexity among dental students enrolled in clinical practice, comparing those with and without neck pain. We used an online Nordic Musculoskeletal Questionnaire for group allocation and center of pressure (CoP) oscillations with a tri-axial Bertec force plate.

View Article and Find Full Text PDF

Prevalence of Lower Back Pain and Risk Factors in Equestrians: A Systematic Review.

Sports (Basel)

December 2024

Escola Superior de Biociências de Elvas, Instituto Politécnico de Portalegre, 7300-110 Portalegre, Portugal.

This systematic review aimed to determine the prevalence of lower back pain (LBP) in equestrian athletes (EAs) and identify associated risk factors. Following the PRISMA guidelines, observational studies published between 2004 and 2024 in English, Portuguese, Spanish, and German were included. The review identified relevant studies through the Web of Science, EBSCO, MEDLINE, and SCOPUS (last search performed on 30 October 2024), yielding 14 studies with a total of 4527 participants.

View Article and Find Full Text PDF

This preliminary study examined the effects of playing walking football with and without a goalkeeper (GK) on physiological, physical, technical, and perceptual variables in older men. Twenty participants (67 ± 4.7 years) engaged in two five vs.

View Article and Find Full Text PDF

Background/objectives: Studies focused on the soccer goalkeeper position in training and official matches are scarce. The present study aimed to analyze the external load during training sessions and official matches in semi-professional goalkeepers.

Methods: Data from goalkeepers (n = 6) from the youth ranks of a professional team belonging to the first Spanish soccer league have been used.

View Article and Find Full Text PDF

(1) Background: Urinary tract infections (UTIs) are caused by the proliferation of pathogenic microorganisms, and they are the second most common hospital-acquired infections, with catheter-associated UTIs (CAUTIs) accounting for about 40% of these nosocomial infections. This review aims to identify the impact of technology on preventing infections in patients with urinary catheters; (2) Methods: The search was conducted in April 2024 through the EBSCOhost platform, with access to the American Search Complete, CINHAL Ultimate, Medline databases, and through the Scopus database; (3) Results: In total were included eight articles in this review. Technology interventions can significantly reduce the incidence of CAUTIs, decrease the duration of catheter use, improve diagnosis, and enhance patient safety; (4) Conclusions: Technological advancements show significant benefits in reducing infection rates and improving patient outcomes, like shorter hospital stays and comfort.

View Article and Find Full Text PDF

Caring for patients in intensive care units (ICUs) requires healthcare workers to recognize the importance of a spiritual care approach in these settings. Moving toward a holistic and patient-centered care model that incorporates spiritual care is essential for enhancing patients' healing process. The disease-centered approach of ICU and the perceived deficit of spiritual care highlight the need to add knowledge on integrating spiritual care interventions into daily ICU practices.

View Article and Find Full Text PDF

The study aim was to compare the external load during varying microcycles (M1-M4 during pre-season and M5 during the in-season) in elite female Portuguese soccer players and to describe external load variations between differing Ms. Fourteen first-team players participated in the study (age 23.29 ± 3.

View Article and Find Full Text PDF

Health-related quality of life after rehabilitation from knee surgery in rural and urban settings: a quasi-experimental study.

BMC Musculoskelet Disord

December 2024

Public Health Research Centre, Comprehensive Health Research Center, NOVA National School of Public Health, CHRC, NOVA University Lisbon, Lisbon, Portugal.

Background: Injury to the knee joint is associated with physical disability, stiffness, pain, restriction of movement and impairment of the person's quality of life, with a few treatment options, including surgery and rehabilitation. This study aims to evaluate the impact of a rehabilitation program on the quality of life reported by patients living in rural and urban areas after knee surgery, using patient-reported outcome measures (PROMs).

Methods: This quasi-experimental study with two groups of participants undergoing primary knee surgery was carried out in two rehabilitation centers, one in an urban area and another in a rural one.

View Article and Find Full Text PDF

Background: Clinical reasoning significantly impacts physicians' performance and patient care quality. Research into learning transfer within clinical reasoning education, especially in managing multimorbidity in Family Medicine, is crucial. This study evaluates the impact of concept maps (CMs) on promoting clinical reasoning skills among undergraduate students, compared to traditional teaching methods (TM).

View Article and Find Full Text PDF

Editorial: Psychological Safety in Healthcare Settings.

Int J Public Health

December 2024

European Researchers' Network Working on Second Victims (ERNST), COST Action 19113, Brussels, Belgium.

View Article and Find Full Text PDF

Cross-Cultural Adaptation and Validation of the Person-Centered Therapeutic Relationship in Physiotherapy Scale to European Portuguese.

Healthcare (Basel)

December 2024

Instituto Politécnico de Setúbal, Escola Superior de Saúde, 2914-503 Setúbal, Portugal.

Background/objectives: Implementing a person-centered practice is considered a priority in healthcare, and the development of a solid and positive therapeutic relationship is a fundamental element. This study conducted a cross-cultural adaptation of the Person-Centered Therapeutic Relationship in Physiotherapy Scale to European Portuguese and contributed to its validation through the study of its structural validity and internal consistency.

Methods: This study was conducted from October 2021 to July 2023 and included two phases: a methodological study of cross-cultural adaptation (phase 1) and a transversal study to assess the psychometric properties (phase 2).

View Article and Find Full Text PDF