1 results match your criteria: "Comprehensive Cancer Center Institute of Cancer Research Medical University of Vienna[Affiliation]"
Specific roles for dendritic cell subsets during initiation and progression of psoriasis.
EMBO Mol Med
October 2014
Department of Medicine I, Comprehensive Cancer Center Institute of Cancer Research Medical University of Vienna, Vienna, Austria
Several subtypes of APCs are found in psoriasis patients, but their involvement in disease pathogenesis is poorly understood. Here, we investigated the contribution of Langerhans cells (LCs) and plasmacytoid DCs (pDCs) in psoriasis. In human psoriatic lesions and in a psoriasis mouse model (DKO* mice), LCs are severely reduced, whereas pDCs are increased.
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