1,106 results match your criteria: "Complications of Dermatologic Laser Surgery"
Photodynamic therapy for oral mucositis in cancer patients- a systematic review and meta-analysis.
Photodiagnosis Photodyn Ther
December 2024
Department of Oral and Maxillofacial Diseases, Helsinki University and University Hospital, Helsinki, Finland; Department of Oral Diseases, Karolinska Institutet, Huddinge, Sweden.
Aim: This systematic review aimed to evaluate the efficacy of photodynamic therapy (PDT) in reducing the severity of chemotherapy-induced oral mucositis, and associated symptoms in cancer patients compared to standard care or other interventions.
Materials And Methods: A comprehensive literature search identified seven relevant studies (randomized controlled trials and non-randomized clinical trials) published between January 1, 2000, and May 31, 2024. The data analysis was carried out using the standardized mean difference as the outcome measure.
Antimicrobial Photodynamic Therapy in the Treatment of Diabetic Foot Ulcer: A Scoping Review.
Photobiomodul Photomed Laser Surg
December 2024
Department of General and Specialized Nursing, University of São Paulo, São Paulo, Brazil.
To map the literature about photodynamic therapy in treating diabetic foot ulcers. Diabetic foot ulcers get constantly infected, thus culminating in hospitalizations and amputations. Photodynamic therapy is an antimicrobial treatment that may assist in the healing process.
View Article and Find Full Text PDFKeloid Formation and Any Skin Complications in Patients Treated With Isotretinoin and Undergone Any Skin-Related Procedures.
J Cosmet Dermatol
November 2024
Department of Dermatology, Rasool Akram Medical Complex Research Development Center (RCRDC), School of Medicine, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Background: Isotretinoin is widely used for moderate to severe acne vulgaris. Despite its broad application, isotretinoin carries a risk of permanent scarring and keloid formation following various skin procedures. As a result, a delay of at least 6-12 months after completing or discontinuing isotretinoin treatment is commonly recommended before undergoing skin procedures.
View Article and Find Full Text PDFPhotodynamic therapy compared with loop electrosurgical excision procedure in patients with cervical high-grade squamous intraepithelial lesion.
Sci Rep
November 2024
Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, No.1120 Lianhua Road, Futian district, Shenzhen, 518036, Guangdong, China.
The study aimed to compare the effectiveness between Hiporfin-photodynamic therapy (PDT) and loop electrosurgical excision procedure (LEEP) in treating cervical high-grade squamous intraepithelial lesion (HSIL). We conducted a retrospective analysis of 104 women diagnosed with cervical HSIL at our hospital from April 2019 to July 2023. With 1:1 matched case-control, 52 cases received Hiporfin-PDT and 52 cases underwent LEEP.
View Article and Find Full Text PDFPhotoimmunotherapy using indocyanine green-loaded Codium fragile polysaccharide and chitosan nanoparticles suppresses tumor growth and metastasis.
J Nanobiotechnology
October 2024
Department of Microbiology, Brain Korea 21 project, University of Ulsan College of Medicine, ASAN Medical Center, Seoul, 05505, South Korea.
Metastasis and recurrence are the main challenges in cancer treatment. Among various therapeutic approaches, immunotherapy holds promise for preventing metastasis and recurrence. In this study, we evaluated the efficacy of treating primary cancer and blocking metastasis and recurrence with photo-immunotherapeutic nanoparticles, which were synthesized using two types of charged polysaccharides.
View Article and Find Full Text PDFOcular Complication in Facial Aesthetic Laser and Light Treatments: A Comprehensive Review.
Diagnostics (Basel)
September 2024
Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea.
Background: The increasing popularity of laser- and light-based esthetic treatments for facial rejuvenation has raised concerns regarding ocular safety. Although these procedures are generally considered safe and effective, there is a growing body of evidence highlighting the potential for ocular complications. This review aims to systematically analyze the types and mechanisms of ocular injuries associated with such treatments, as well as to evaluate preventive measures and management strategies.
View Article and Find Full Text PDFEffective Technique Using Combined CO Laser and Pulsed Dye Laser for Facial Angiofibromas Management in Tuberous Sclerosis.
Case Rep Dermatol Med
September 2024
Lasers in Dermatology Unit University of Rome Tor Vergata, Rome, Italy.
Article Synopsis
- Facial angiofibromas (FAs) are skin growths commonly associated with tuberous sclerosis (TS) and can significantly affect appearance.
- A 23-year-old male with TS was treated for multiple FAs on his face using a combination of ablative CO laser and pulsed dye laser over three sessions, spaced two months apart.
- The treatment resulted in significant improvement of the lesions without any severe side effects, demonstrating it as a safe and effective option for managing FAs in young patients with TS.
Navigating Laser Treatments for Scars: The Physical and Emotional Journey.
J Cosmet Dermatol
November 2024
Hospital Ramon y Cajal, Universidad de Alcala, Madrid, Spain.
Article Synopsis
- This study explores the impact of scars on individuals' lives, highlighting the emotional and physical burdens they cause, and emphasizes a solution-centered approach rather than just medical facts.
- The pilot study involved 60 patients assessing their scars and quality of life using specific scales, and results showed significant improvements in both physical scar conditions and overall quality of life after treatment.
- The findings indicate that scars not only affect physical appearance but also have considerable psychological repercussions, influencing self-image and social interactions, which underscores the importance of a holistic treatment approach in dermatology.
Article Synopsis
- Acne can lead to significant skin issues like scarring and post-inflammatory changes, which can severely affect the mental well-being of patients, particularly those with skin of color.
- The study explored the effectiveness of a combined treatment approach using non-ablative laser therapy and a topical antioxidant blend (SSAF) for improving skin issues related to acne in patients of diverse skin types.
- Results showed that combining SSAF with laser treatment led to a more noticeable reduction in pigmentation issues and improved collagen density, especially among patients with skin of color, although the study had a small sample size and limited follow-up period.
Phosphate Ion-Responsive and Calcium Peroxide-Based Nanomedicine for Bone-Targeted Treatment of Breast Cancer Bone Metastasis.
Adv Healthc Mater
December 2024
State Key Laboratory of New Pharmaceutical Preparations and Excipients, Key Laboratory of Medicinal Chemistry and Molecular Diagnosis of the Ministry of Education, Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Material Science, Hebei University, Baoding, 071002, China.
The treatment of breast cancer bone metastasis is an unresolved clinical challenge, mostly because currently therapeutic approaches cannot simultaneously block the tumor growth and repair the osteolytic bone injuries at the metastatic site. Herein, the study develops a novel nanomedicine to treat breast cancer bone metastasis. The nanomedicine is based on phosphate ion-responsive and calcium peroxide-based nanoparticles carrying the bone-targeting agent zoledronic acid on the surface and loaded with the photosensitizer indocyanine green.
View Article and Find Full Text PDFA Triple Laser Combination Treatment for Facial Angiofibromata Management in Tuberous Sclerosis and Literature Review.
Arch Plast Surg
July 2024
Hellenic Society of Dermatology Surgery (HSDS), Private Dermatological Clinic 'Laserderm Academy', Athens, Greece.
Article Synopsis
- * A new triple laser therapy protocol was tested on 10 patients with tuberous sclerosis over 22 years, which showed effective management of angiofibromas without serious complications.
- * After two years of follow-up, most patients had significant improvement in their condition and reported a high satisfaction rate, suggesting this laser therapy is safe and effective for managing angiofibromas.
Treatment of Iron-Induced Cutaneous Hyperpigmentation With Energy-Based Devices.
Lasers Surg Med
September 2024
Department of Dermatology, University of California, Irvine, Irvine, California, USA.
Article Synopsis
- Iatrogenic cutaneous siderosis is a skin condition characterized by dark patches near injection sites from iron infusions, causing aesthetic and psychological issues for patients, and often doesn't resolve on its own.
- A systematic review of the effectiveness of energy-based devices to treat this condition included 54 female patients, mostly around 44 years old, primarily affected after intravenous iron infusion for iron deficiency anemia.
- Six different laser systems were analyzed, showing over half of patients experienced complete clearance after an average of 5.4 treatments, with the Nd:YAG 532 nm laser showing the best results in the case discussed.
Management of small wounds: result of an Italian survey.
Ital J Dermatol Venerol
October 2024
Dermatology Clinic, University of Catania, Catania, Italy -
Article Synopsis
- Infection at surgical sites is common after dermatologic procedures, but using antibiotics to prevent these infections is controversial due to rising antibiotic resistance, especially in Italy where misuse is rampant.* -
- A survey distributed to dermatologists nationwide revealed that over 70% routinely use topical antibiotics post-procedure, despite growing evidence against their effectiveness in preventing infections.* -
- The results indicate a significant misunderstanding about the role of antibiotics in wound care, highlighting the urgent need for education among healthcare professionals to combat the ongoing issue of antibiotic resistance.*
An Overview on the Management of Atrophic Acne Scars: The Role of Trifarotene as an Adjunct.
Skin Therapy Lett
July 2024
Department of Dermatology and Skin Science, University of British Columbia, Vancouver, BC, Canada.
Article Synopsis
- Acne vulgaris is a widespread inflammatory skin condition that affects people of all ages and can lead to lasting effects like scarring and color changes, which significantly impact mental health.
- Treatment for acne scarring involves various methods including topical creams, physical procedures, and laser therapies, with the best results often seen using a combination of these approaches.
- Trifarotene is a new type of retinoid approved for moderate-to-severe acne in people over 12, showing promise in treating acne scarring by specifically targeting a common receptor in the skin.
Safety and Efficacy of Epithelium-Off Corneal Collagen Cross-Linking for the Treatment of Corneal Ectasia: A Report by the American Academy of Ophthalmology.
Ophthalmology
October 2024
Department of Ophthalmology, Mayo Clinic, Scottsdale, Arizona.
Article Synopsis
- The text reviews the safety and effectiveness of epithelium-off corneal collagen cross-linking (CXL) as a treatment for progressive corneal ectasia, specifically keratoconus (KCN) and ectasia after refractive surgery.
- A comprehensive literature search led to the inclusion of 6 high-quality randomized clinical trials, all showing positive outcomes, including decreased progression rates and improved visual acuity in patients undergoing treatment compared to controls.
- The findings indicate that epithelium-off CXL is effective in managing KCN and post-refractive surgery ectasia with a low incidence of complications, suggesting a favorable safety profile.
Case Report: Recalcitrant oral lichen planus involving bilaterally buccal mucosae treated with a combination of photodynamic and photobiomodulation therapies.
F1000Res
June 2024
Department of Oral and Maxillofacial Surgery, Khon Kaen University, Nai Mueang, Khon Kaen, 40002, Thailand.
Article Synopsis
- Managing oral lichen planus (OLP), a painful condition, can be tough, but laser therapy is being explored as a treatment alternative to traditional corticosteroids.* -
- A case study of a 43-year-old Thai male with severe bilateral OLP showed improvement after combining photodynamic therapy (PDT) with photobiomodulation therapy (PBMT), despite previous treatments failing.* -
- The patient experienced relief from discomfort and a reduction in lesions after ten PDT sessions and five PBMT sessions, suggesting that this combined approach is effective for persistent OLP cases.*
Efficacy and Safety of the Modified Cretan Protocol in Patients with Post-LASIK Ectasia.
Turk J Ophthalmol
June 2024
Lokman Hekim University, Akay Hospital, Clinic of Ophthalmology, Ankara, Türkiye
Article Synopsis
- The study aimed to assess the safety and effectiveness of the modified Cretan protocol in treating post-laser in situ keratomileusis ectasia (PLE) in 16 patients.
- Results showed that both uncorrected and best corrected visual acuity remained stable after 24 months, with significant improvements in corneal topographic measurements.
- The modified Cretan protocol was deemed safe, with no complications reported, but further research is suggested to validate these findings.
Combinations of Energy-based Devices plus isotretinoin for management of acne and acne scars: A systematic review.
J Cosmet Dermatol
October 2024
Department of Dermatology, West China Hospital, Sichuan University, Chengdu, China.
Article Synopsis
- A systematic review investigates the safety, efficacy, and patient satisfaction of combining systemic isotretinoin (ISO) with energy-based devices (EBD) for treating acne and scarring, despite a recommended 6-month waiting period between treatments.
- The review analyzed data from 16 studies, which included various research designs, and evaluated technologies like intense pulsed light and different types of lasers for their effectiveness and safety when used with ISO.
- The findings suggest that there’s no need to delay EBD treatments after ISO, with certain modalities being safe and effective for improving acne severity and scarring.
Interventions for postburn pruritus.
Cochrane Database Syst Rev
June 2024
Department of Comparative Biology and Experimental Medicine, University of Calgary, Calgary, Canada.
Article Synopsis
- Postburn pruritus is a frustrating symptom for individuals with healing or healed burn wounds, prompting the search for effective treatments.
- A systematic review was conducted to evaluate the effectiveness of various interventions for postburn itch, analyzing 25 randomized controlled trials (RCTs) with over 1,166 participants.
- The interventions examined included neuromodulatory agents, topical therapies, physical modalities, laser treatments, and electrical stimulation, highlighting a range of approaches but leaving the effectiveness of each option still somewhat uncertain.
Complications of dermatologic lasers in high Fitzpatrick phototypes and management: an updated narrative review.
Lasers Med Sci
June 2024
Departament of Dermatology, Hospital de Santa Maria, Lisbon, Portugal.
Article Synopsis
- - The article discusses the complexities of laser surgery, focusing on the risks and complications that can arise during procedures on patients with darker skin types (Fitzpatrick phototypes IV to VI).
- - Higher Fitzpatrick phototypes have unique biological traits that increase their vulnerability to complications during laser treatments, highlighting the importance of specialized knowledge in this area.
- - The research calls for improved expertise and a cautious approach to laser surgery for individuals with darker skin to enhance patient safety and treatment outcomes.
Energy-storing DNA-based hydrogel remodels tumor microenvironments for laser-free photodynamic immunotherapy.
Biomaterials
September 2024
Frontiers Science Center for Synthetic Biology, Key Laboratory of Systems Bioengineering (MOE), School of Chemical Engineering and Technology, Tianjin University, Tianjin, 300350, PR China; Department of Chemistry, State Key Laboratory of Molecular Engineering of Polymers, Shanghai Key Laboratory of Molecular Catalysis and Innovative Materials, College of Chemistry and Materials, Fudan University, Shanghai, 200438, PR China. Electronic address:
Article Synopsis
- Photodynamic therapy (PDT) is a new way to treat cancer, but it has some problems like not reaching deep enough into the body and dealing with tricky tumor environments.
- Scientists created a special DNA-based gel that can help treat tumors without using external light and can adjust the tumor’s surroundings to make the treatment more effective.
- In tests on mice with breast cancer, this new gel was able to reduce tumor size by about 78.3%, showing it could be a great new option for battling cancer.
Combined topography-guided photorefractive keratectomy and corneal collagen crosslinking.
Indian J Ophthalmol
July 2024
Department of Ophthalmology, Minto Ophthalmic Hospital, Regional Institute of Ophthalmology, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
Article Synopsis
- The study investigated the long-term effects of combining topography-guided photorefractive keratectomy (PRK) and accelerated corneal collagen cross-linking (CXL) for treating mild-to-moderate keratoconus using a specific refractive system.
- Conducted at a tertiary eye care hospital in South India, the study involved 30 patients whose visual acuity and keratometry measurements were evaluated at multiple time points post-surgery.
- Results showed significant improvements in uncorrected and corrected distance visual acuity, as well as decreased keratometry values over 24 months, suggesting this combined procedure could be an effective treatment for early keratoconus, though further research is needed to solidify these
Picosecond alexandrite laser treatment of nevus of Ota in children.
Lasers Surg Med
July 2024
Department of Cosmetic Laser Surgery, Hospital of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Article Synopsis
- The study assessed the use of a 755nm picosecond alexandrite laser for treating nevus of Ota in children, finding it to be safe and effective.
- A group of 305 pediatric patients achieved an average of 79% pigment clearance after about two treatments, with younger patients and those with darker lesions showing better results.
- Complications occurred in 12.1% of cases, mostly post-inflammatory hyperpigmentation, but the overall findings support early and frequent treatment for optimal outcomes.
Article Synopsis
- Acne is a common skin condition that significantly affects the self-confidence and social interactions of patients, especially those of Asian descent, due to increased susceptibility to scarring and hyperpigmentation.
- Many Asia-Pacific countries lack comprehensive guidelines for acne management, contributing to suboptimal care, and existing guidelines often do not get updated regularly.
- The article emphasizes the need for better understanding and management of acne treatments, highlighting the efficacy of topical retinoids, particularly trifarotene, which has shown promise in reducing acne scars.
Article Synopsis
- There's a growing focus on ethnic dermatology as skin of color populations increase worldwide, facing challenges like hyperpigmentation disorders that are hard to treat with standard therapies.
- Recent research highlights the development of laser technologies aimed at different types of hyperpigmentation, emphasizing the importance of understanding these advancements for effective treatment.
- A study with 122 Indian patients showed that specific laser combinations led to significant improvement in pigmentation issues, demonstrating the potential effectiveness of these technologies in various skin types, particularly darker Fitzpatrick categories.