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Complejo Hospitalario Universitario A C... Publications | LitMetric

336 results match your criteria: "Complejo Hospitalario Universitario A Coruña (CHUAC)[Affiliation]"

Article Synopsis
  • COVID-19 led to a global pandemic in 2020, creating a need for efficient decision-making by medical staff with limited resources during healthcare emergencies.
  • The study introduces an automated method that utilizes multimodal data fusion, combining clinical features and deep learning from chest X-ray images, to estimate the risks of hospitalization and mortality for COVID-19 patients.
  • Results indicate high accuracy in risk assessment (AUC-ROC scores of 0.8452 and 0.8285 for hospitalization and mortality, respectively) and show that incorporating imaging features improves hospitalization risk evaluation, while clinical features are more critical for mortality, emphasizing the approach's potential to enhance clinical decision-making across various medical scenarios.
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Extracellular gadolinium-based contrast agents (GBCA) are commonly used in magnetic resonance imaging (MRI) because they increase the detection of alterations, improve tissue characterisation and enable a more precise differential diagnosis. GBCAs are considered to be safe but they are not risk-free. When using GBCAs, it is important to be aware of the risks and to know how to react in different situations (pregnancy, breastfeeding, kidney failure) including if complications occur (extravasations, adverse, allergic or anaphylactic reactions).

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Introduction: Respiratory diseases encompass a diverse range of conditions that significantly impact global morbidity and mortality. While common diseases like asthma and COPD exhibit moderate symptoms, less prevalent conditions such as pulmonary hypertension and cystic fibrosis profoundly affect quality of life and mortality. The prevalence of these diseases has surged by approximately 40% over the past 3 decades.

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Is There Apical Sparing Pattern During Stress in Cardiac Amyloidosis?

Echocardiography

October 2024

Department of Cardiology, Complejo Hospitalario Universitario de A Coruña (CHUAC), CIBERCV, Instituto de Investigación Biomédica de A Coruña (INIBIC), Universidad de A Coruña, A Coruña, Spain.

Article Synopsis
  • - Case 1 shows an abnormal strain (AS) pattern both at rest (2.4) and peak exercise (2.6), alongside global 3D longitudinal strain values of -9.9 at rest and -7.8 at peak.
  • - Case 2 has no abnormal strain pattern at rest (AS = 0.78), but exhibits an abnormal pattern during peak exercise (AS = 1.53) with the "cherry on top" pattern present only during exercise.
  • - The global 3D strain values for Case 2 are -8.3 at rest and decrease to -4.3 at peak exercise, indicating a significant change in strain under exercise conditions.
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Impact of left ventricular unloading on postheart transplantation outcomes in patients bridged with VA-ECMO.

Rev Esp Cardiol (Engl Ed)

October 2024

Servicio de Cardiología, Complejo Hospitalario Universitario de A Coruña (CHUAC), Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain; Facultad de Ciencias de la Salud, Universidad de A Coruña, A Coruña, Spain.

Article Synopsis
  • * A total of 245 patients were analyzed, with 54.3% using mechanical LV unloading techniques, primarily the intra-aortic balloon pump, showing an improved 1-year survival rate of 74.4% compared to 59.8% in those without LV unloading.
  • * The findings suggest that preoperative LV unloading is linked to better survival rates after a year post-transplant, with no notable differences in other postoperative complications between groups.
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Article Synopsis
  • The study investigates the genetic factors linked to severe COVID-19, specifically focusing on hospitalized cases in admixed Americans.
  • Researchers conducted the largest genome-wide association study (GWAS) for COVID-19 hospitalization in this population, identifying four significant genetic associations, including two novel loci found in Latin Americans.
  • The findings highlight the importance of including diverse populations in genomic research, aiming to improve understanding of genetic risks associated with COVID-19 across different ethnic groups.
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Current antibiograms cannot discern the particular effect of a specific antibiotic when the bacteria are incubated with a mixture of antibiotics. To prove that this task is achievable, strains were treated with ciprofloxacin for 45 min, immobilized on a slide and stained with SYBR Gold. In susceptible strains, the nucleoid relative surface started to decrease near the MIC, being progressively condensed as the dose increased.

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[Not Available].

Farm Hosp

January 2024

Dirección Asistencial, Área Sanitaria de A Coruña e Cee, A Coruña, Spain; Grupo de Virología Clínica, Instituto de Investigación Biomédica de A Coruña (INIBIC)-Complejo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidad de A Coruña (UDC), A Coruña, Spain. Electronic address:

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Cross-sectional and longitudinal associations of adherence to WCRF/AICR cancer prevention recommendations with health-related quality of life in breast cancer survivors. Health-EpiGEICAM study.

J Nutr Health Aging

August 2024

Unidad de Epidemiología del Cáncer y Ambiental, Departamento de Epidemiología de Enfermedades Crónicas, Centro Nacional de Epidemiología (CNE), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; CIBER de Epidemiología y Salud Pública, Instituto de Salud Carlos III (CIBERESP, ISCIII), Madrid, Spain; GEICAM Spanish Breast Cancer Research Group, Madrid, Spain.

Article Synopsis
  • - The study investigates how following cancer prevention guidelines from the WCRF/AICR affects the health-related quality of life (HRQL) in breast cancer survivors over a long period, specifically comparing their status at diagnosis and 7-12 years later.
  • - Researchers analyzed data from 406 breast cancer survivors, collecting information on lifestyle, diet, physical activity, and HRQL using a scoring system based on WCRF/AICR recommendations.
  • - Results indicate that higher adherence to these cancer prevention guidelines is linked to slight improvements in the physical aspect of HRQL over time, while no significant change was found in the mental HRQL domain.
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Stratification tools in the follow-up of people living with HIV, are they necessary and applicable?

Farm Hosp

July 2024

Dirección Asistencial, Área Sanitaria de A Coruña e Cee, A Coruña, España; Grupo de Virología Clínica, Instituto de Investigación Biomédica de A Coruña (INIBIC)-Complejo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidad de A Coruña (UDC), A Coruña, España. Electronic address:

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Background: Levodopa-induced dyskinesias (LID) are frequent in Parkinson's disease (PD).

Objective: To analyze the change in the frequency of LID over time, identify LID related factors, and characterize how LID impact on patients' quality of life (QoL).

Patients And Methods: PD patients from the 5-year follow-up COPPADIS cohort were included.

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Predicting the development of heart failure in patients with atrial fibrillation.

Rev Esp Cardiol (Engl Ed)

September 2024

Servicio de Cardiología, Complejo Hospitalario Universitario de A Coruña (CHUAC), Instituto de Investigación Biomédica de A Coruña (INIBIC), A Coruña, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Spain. Electronic address:

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Objective: To develop multidisciplinary recommendations based on available evidence and expert consensus for the therapeutic management of patients with refractory Behçet's syndrome (BS) (difficult to treat, severe resistant, severe relapse) to conventional treatment.

Methods: A group of experts identified clinical research questions relevant to the objective of the document. These questions were reformulated in PICO format (patient, intervention, comparison and outcome).

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Purpose: To evaluate the efficacy and safety of first-line therapy with palbociclib in a Spanish cohort treated after palbociclib approval.

Methods: PALBOSPAIN is an observational, retrospective, multicenter study evaluating real-world patterns and outcomes with 1 L palbociclib in men and women (any menopausal status) with advanced HR/HER2- BC diagnosed between November 2017 and November 2019. The primary endpoint was real-world progression-free survival (rw-PFS).

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To delineate the phenotype of erosive hand osteoarthritis (EHOA) in a Spanish population and assess its correlation with metabolic syndrome. We conducted a cross-sectional study using baseline data from the Prospective Cohort of Osteoarthritis from A Coruña (PROCOAC). Demographic and clinical variables, obtained through questionnaires, clinical examinations, and patient analytics, were compared among individuals with hand OA, with and without EHOA.

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Prognostic impact of chronic obstructive pulmonary disease and bronchial asthma in patients with heart failure.

Rev Clin Esp (Barc)

March 2024

Servicio de Cardiología, Complejo Hospitalario Universitario de A Coruña (CHUAC), Instituto de Investigación Biomédica de A Coruña (INIBIC), Servicio Galego de Saúde (SERGAS), A Coruña, Spain; Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Madrid, Spain; Universidad de A Coruña (UDC), A Coruña, Spain.

Purpose: To analyze the impact of chronic obstructive pulmonary disease (COPD) and bronchial asthma on therapeutic management and prognosis of patients with heart failure (HF).

Methods: Analysis of the information collected in a clinical registry of patients referred to a specialized HF unit from January-2010 to June-2012. Clinical profile, treatment and prognosis of patients was evaluated, according to the presence of COPD or asthma.

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Acute myeloid leukemia has a poor prognosis in older adults, and its management is often unclear due to its underrepresentation in clinical trials. Both overall survival (OS) and health-related quality-of-life (HRQoL) are key outcomes in this population, and patient-reported outcomes may contribute to patient stratification and treatment assignment. This prospective study included 138 consecutive patients treated in daily practice with the currently available non-targeted therapies (intensive chemotherapy [IC], attenuated chemotherapy [AC], hypomethylating agents [HMA], or palliative care [PC]).

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A multitrait genetic study of hemostatic factors and hemorrhagic transformation after stroke treatment.

J Thromb Haemost

April 2024

Genomics of Complex Disease Group, Institut de Recerca Sant Pau (IR SANT PAU), Barcelona, Spain; Cardiovascular Medicine Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

Article Synopsis
  • Scientists studied a medicine called r-tPA that helps treat strokes but can cause bleeding in the brain, making things worse for patients.
  • They looked at certain genetic factors in the body that might affect this bleeding risk after using r-tPA.
  • They found some specific genes that are linked to both blood clotting factors and the risk of bleeding, which could help in understanding how to treat patients better in the future.
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Article Synopsis
  • Various neoadjuvant treatments for advanced colon cancer are becoming available, and effective preoperative staging is essential for choosing the right approach.
  • A study involving 50 centers and 1,950 patients focused on the diagnostic accuracy of CT scans for T4 colon tumors, revealing significant limitations in terms of sensitivity and specificity for staging.
  • The findings indicated that while CT had high accuracy for detecting peritoneal metastases, its overall performance for T4 staging and lymph node classification was inadequate, highlighting the need for improved diagnostic methods.
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Fulminant myocarditis proven by early biopsy and outcomes.

Eur Heart J

December 2023

Medical Intensive Care Unit, Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Paris Cedex 13, France.

Article Synopsis
  • Endomyocardial biopsy (EMB) is important for diagnosing fulminant myocarditis in adults, but its timing and effects on patient outcomes are still being studied.
  • In a study involving 419 patients across 36 centers, those who had an early EMB (within 2 days of ICU admission) showed significantly better survival rates (63%) without needing heart transplants or LVAD compared to those with delayed EMB (40%).
  • The research suggests that early EMB is associated with lower mortality rates and better overall outcomes, supporting its prompt use in ICU patients suspected of having fulminant myocarditis.
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Staging Parkinson's disease according to the MNCD classification correlates with caregiver burden.

Brain Behav

December 2023

Department of Neurology, Unidad de Trastornos del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen del Rocío/CSIC/Universidad de Sevilla, Seville, Spain.

Background And Objective: Recently, we demonstrated that staging Parkinson's disease (PD) with a novel simple classification called MNCD, based on four axes (motor, non-motor, cognition, and dependency) and five stages, correlated with disease severity and patients' quality of life. Here, we analyzed the correlation of MNCD staging with PD caregiver's status.

Patients And Methods: Data from the baseline visit of PD patients and their principal caregiver recruited from 35 centers in Spain from the COPPADIS cohort from January 2016 to November 2017 were used to apply the MNCD total score (from 0 to 12) and MNCD stages (from 1 to 5) in this cross-sectional analysis.

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Response to levodopa in Parkinson's disease over time. A 4-year follow-up study.

Parkinsonism Relat Disord

November 2023

Unidad de Trastornos Del Movimiento, Servicio de Neurología y Neurofisiología Clínica, Instituto de Biomedicina de Sevilla, Hospital Universitario Virgen Del Rocío/CSIC/Universidad de Sevilla, Seville, Spain; CIBERNED (Centro de Investigación Biomédica en Red Enfermedades Neurodegenerativas), Spain.

Background And Objective: A good response to levodopa is a key factor to indicate device-aided therapies in people with Parkinson's disease (PwPD). The aim of the present study was to analyze the response to levodopa in PwPD with motor fluctuations followed for 4 years.

Patients And Methods: PwPD with motor fluctuations recruited from January 2016 to November 2017 from the COPPADIS cohort and assessed annually (from baseline to 4-year follow-up) during the OFF and ON states were included in this analysis.

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