Correlation between conventional karyotype, interphase FISH and immunophenotype in risk stratification of newly diagnosed plasma cell myeloma: An observational study.

Background: Plasma cell myeloma (PCM) is a common adult hematological neoplasm of terminally differentiated B-cells resulting in accumulation of monoclonal plasma cells. PCM is heterogeneous disease with survival time varies from months to years, determined by age, stage, cytogenetics abnormalities, and treatment response. There is conflicting evidence in role of immunophenotype as a prognostic indicator.

Harmonic-to-noise ratio as speech biomarker for fatigue: K-nearest neighbour machine learning algorithm.

Background: Vital information about a person's physical and emotional health can be perceived in their voice. After sleep loss, altered voice quality is noticed. The circadian rhythm controls the sleep cycle, and when it is askew, it results in fatigue, which is manifested in speech.

Dual phase multidetector computed tomography angiography in evaluation of pulmonary arteries and collateral vessels in children with cyanotic congenital heart diseases.

Background: The purpose of this paper is to compare the efficacy of dual-phase multidetector computed tomography angiography (CTA) with transthoracic echocardiogram (TTE) and cardiac catheterization angiography (CCA) in evaluation of pulmonary arteries and collateral vessels, major aortopulmonary collateral arteries (MAPCAs) in children with cyanotic congenital heart diseases.

Methods: The study was a prospective observational study where 32 pediatric patients (18 males, 14 females and age range 2-116 months) with cyanotic congenital heart diseases (CCHD) were included. All patients underwent TTE, CTA, and CCA.

Study of Caregiver Burden in Continuous Ambulatory Peritoneal Dialysis.

Background: Increased caregiver burden undermines caregivers' mental and physical health and is an under recognized but critical aspect for the success of continuous ambulatory peritoneal dialysis (CAPD). This study was undertaken to quantify and identify the factors determining CAPD caregiver burden.

Materials And Methods: A cross-sectional study was conducted among 51 caregivers of CAPD patients visiting the centers from July to August 2023.

Accuracy of femoral tunnel placement using three different techniques in performing arthroscopic all-inside anterior Cruciate Ligament reconstruction; A randomized study.

Background: One of the key steps in arthroscopic Anterior Cruciate Ligament Reconstruction (ACLR) is getting the femoral tunnel at the right position to attach the graft. While the correct position has been described as a low and posterior position behind the bifurcate ridge on the medial surface of lateral femoral condyle, to reproducibly achieve it more than one technique is being used by surgeons. There are no randomized studies in literature which have evaluated the efficacy of these in a surgeon's hand.

Grommet Insertion on Stretched Glove over ear Speculum: A Novel Training Technique.

Introduction: Grommet insertion is a common procedure in field of Otology. Its outcome depends highly on degree of experience of the surgeon.

Materials And Methods: Simulation in training and clinical practice is an important facet in a surgeon's life.

Pneumolabyrinth in a Case of Squamous Chronic Otitis Media - a Rare Entity.

Pneumolabyrinth is a rare entity in a case of squamous chronic otitis media in the practice of otology. We report a case of 56 year male, a known case of Squamous Chronic Otitis Media who was diagnosed as a case of Pneumolabyrinth associated with a Perilymphatic fistula. Diagnosis was done with the help of audiometry and High-Resolution Computed Tomography of Temporal Bone in background of his symptoms.

From Ancient Remedies to Robotic Precision: An Otolaryngology Journey.

This review traces the historical development of otolaryngology, a medical specialty focused on diagnosing and treating ear, nose, and throat (ENT) disorders. The paper highlights key milestones and innovations shaping the field from ancient times to the modern era. The study involves a comprehensive review of historical texts and medical literature, examining advancements in otolaryngology.

Voice Rehabilitation after tongue cancer surgery: a cohort study in indian population.

Unlabelled: Tongue cancer significantly impacts speech and swallowing functions, necessitating comprehensive rehabilitation post-surgery. This study evaluates the rehabilitation outcomes of Indian patients who underwent tongue cancer surgery, focusing on speech therapy, nutritional support, and psychosocial interventions. A prospective cohort study was conducted from January 2021 to December 2022 at a tertiary care center in India.

Evolving Trends in Safe Surgery in Otolaryngology: Experience from a Tertiary Care Centre.

Unlabelled: Surgical outcomes in otolaryngology have improved with advancements in safety protocols, technology, and patient-centered care. Despite these improvements, surgical complications remain a concern, necessitating continuous evaluation. This study aimed to examine the trends in safe surgery practices and patient outcomes over two years at a tertiary care otolaryngology center, focusing on preoperative, intraoperative, and postoperative phases, as well as patient involvement in decision-making.

Impact of Adenoidectomy on Emotional, Social, and Academic Development in Children: A Longitudinal Cohort Study.

Unlabelled: Adenoid hypertrophy (AH) is a common condition in children, leading to obstructive sleep apnea (OSA), recurrent infections, and nasal breathing issues, which impact emotional and social growth. Although adenoidectomy is a common treatment, its broader effects on emotional, social, and academic development are underexplored. This longitudinal observational cohort study, conducted from January 2020 to December 2021 at a tertiary care center, involved 200 children aged 4 to 10 years with AH.

Building psychological resilience among families of service personnel.

Psychological resilience means adapting positively to adversity. This is armed forces' very context and function-encountering, enduring, and overcoming challenging situations through resilience. Scientific study of psychological resilience has moved from individual, to process, onward to developmental trajectories, and to neuro-biological underpinnings.

Capsular vascularization: role of suprachoroidal triamcinolone and histopathology.

Introduction: Neovascularization of the lens is a rare entity linked to lens-induced inflammation due to many causes like trauma. We describe a case managed using suprachoroidal triamcinolone, an anti-VEGF injection, in conjunction with cataract surgery and IOL implantation.

Patient And Clinical Findings: A male patient, 27, presented with a severe reduction in vision in his right eye (RE) accompanied by redness for one month.

Optical Density and Polarized Light Microscopy to confirm calcification of Intra-ocular Lens.

Introduction: Intra-ocular lens (IOL) calcification is a rare yet serious complication, presenting as clouding within the optics of IOL and necessitating IOL exchange.

Patient And Clinical Findings: In this case, a 77-year-old male experienced gradual vision loss in his left eye (LE) over four years post-cataract surgery a decade before. His best corrected visual acuity (BCVA) was 3/60 in the LE, with the anterior segment displaying a clear cornea but an opacified IOL within the capsular bag.

Cognitive Benefits of Hearing Aids in Elderly Indian Population: A Longitudinal Study.

Unlabelled: Age-related hearing loss is common among older individuals and is linked to cognitive impairment and a decrease in overall quality of life. Although hearing aids enhance auditory capabilities, their influence on cognitive performance in the Indian context has not been thoroughly investigated. This study investigates the cognitive benefits of hearing aids in elderly Indian patients with age-related hearing loss.

Tracking Magnesium Dynamics in Bell's Palsy: Correlations with Disease Progression and Recovery.

Unlabelled: This study investigates the relationship between serum magnesium levels and recovery outcomes in Bell's Palsy patients, aiming to elucidate magnesium's potential neuroprotective role in this condition. Conducted as a prospective cohort study at a tertiary care hospital, 50 Bell's Palsy patients had their serum magnesium levels measured at diagnosis and at 1 week, 1 month, 3 months, and 6 months post-diagnosis. Recovery was assessed using the House-Brackmann scale.

Assessment of the Level of Awareness and Degree of Implementation of Central Line Bundles for Prevention of Central Line-associated Blood Stream Infection: A Questionnaire-based Observational Study.

Aim: The objective of this study was to assess the extent of knowledge and application of central line bundles in the intensive care unit (ICU) of a tertiary care hospital for the purpose of avoiding central line-associated bloodstream infections (CLABSI). This assessment was conducted through the use of a questionnaire.

Materials And Methods: A cross-sectional study was conducted in the ICU, involving doctors and nurses.