2 results match your criteria: "Comenius University Children's Hospital Bratislava[Affiliation]"
Relapse remains the major cause of treatment failure in children with high-risk acute lymphoblastic leukaemia (ALL) undergoing allogeneic haematopoietic stem-cell transplantation (allo-SCT). Prognosis is considered dismal but data on risk factors and outcome are lacking from prospective studies. We analysed 242 children with recurrence of ALL after first allo-SCT enrolled in the Berlin-Frankfurt-Munster (BFM) ALL-SCT-BFM 2003 and ALL-SCT-BFM international 2007 studies.
View Article and Find Full Text PDFProtothecal peritonitis in child after bone marrow transplantation: case report and literature review of paediatric cases.
New Microbes New Infect
November 2014
Department of Paediatric Haematology and Oncology, Haematopoietic Stem Cell Transplantation Unit, Comenius University Children's Hospital Bratislava, Slovakia.
Article Synopsis
- The case details a rare protothecal infection caused by Prototheca wickerhamii in a pediatric stem cell recipient, highlighting the challenges of treatment due to antifungal resistance.
- The review of 13 pediatric cases since 1980 shows that although protothecosis typically has a low mortality rate, this patient succumbed to multi-organ failure exacerbated by complications and a resistant strain of the algae.
- The literature lacks clear treatment guidelines, but successful therapies have included amphotericin B and azoles, emphasizing the need for awareness of unusual pathogens as immunocompromised populations grow.