Helminth diversity of nutria () across the Morava basin in the Czech Republic.

The nutria was introduced to Europe from South America and kept for the fur industry. This semiaquatic rodent became a well-established species in the Czech Republic; however, it still poses a significant threat to the native fauna, not only as a natural competitor but also as a vector of non-indigenous parasites. Our research aimed to investigate the diversity of endoparasitic helminths in nutria, with a particular focus on assessing the risk posed by helminth species with zoonotic potential.

Longitudinal Assessment of Cognitive Function in Survivors of Testicular Germ Cell Tumor.

Background And Objective: Survivors of testicular germ cell tumor (TGCT) may experience long-term cognitive changes. The aim of our prospective study was to longitudinally assess cognitive function among TGCT survivors to identify potential lasting cognitive changes over a period of 5 yr.

Methods: TGCT survivors (n = 151) completed Functional Assessment of Cancer Therapy-Cognitive Function (FACT-Cog) questionnaires annually, with median time to first follow-up visit (FUV) of 8 (range 4-24) yr since completion of treatment.

Temperature-dependent sleep patterns in Drosophila.

Sleep is a fundamental physiological process conserved through evolution, from worms to humans. Understanding how temperature influences sleep is essential for comprehending the complexities of animal behavior, physiology, and their adaptations to thermal environments. This study explores the impact of temperature on sleep behavior and patterns in Drosophila melanogaster.

Pharmacist-led interventions for vascular surgery patients: a prospective study on reducing drug-related problems.

Background: Vascular surgery patients are at a high risk of polypharmacy and drug-related problems. Only a limited number of studies have explored the impact of hospital pharmacists being members of a multidisciplinary team in the care of vascular surgery patients. The clinical study (Trial Registration Number NCT04930302, 16 June 2021) aimed to assess the impact of pharmacist-led interventions on the prevalence of drug-related problems among patients hospitalised at the vascular surgery department.

Vavro Šrobár: Slovak politician and publicist as a medical doctor involved (also) in the history of medicine.

Vavro Šrobár was a prominent political figure in East-Central Europe. He played a pivotal role in the establishment and development of the First Czechoslovak Republic, which emerged following the dissolution of the Austro-Hungarian Empire. He was the first Minister to exercise full administrative authority in overseeing the Provisional Government of Slovakia, and throughout his career, including until the end of his life, he held several significant political positions, such as Minister of Public Health and Physical Education, Minister of Unification, Minister of Education and National Enlightenment, and Minister of Finance.

Adolescents' Wellbeing at School: What Helps and What Hinders From Feeling Safe and Satisfied?

Objectives: The aim of this qualitative study was to identify the main factors that help and hinder adolescents' wellbeing at school using their perspectives and experiences.

Methods: We used data from 45 adolescents in the first year of high school in Slovakia (mean age = 14.98; 22.

P , T -odd effects in YbCu, YbAg, and YbAu.

In this work, the molecular enhancement factors of the P,T-odd interactions involving the electron electric dipole moment (Wd) and the scalar-pseudoscalar nucleon-electron couplings (Ws) are computed for the ground state of the bimetallic molecules YbCu, YbAg, and YbAu. These systems offer a promising avenue for creating cold molecules by associating laser-cooled atoms. The relativistic coupled-cluster approach is used in the calculations, and a thorough uncertainty analysis is performed to give accurate and reliable uncertainties to the obtained values.

Three Decades of Adolescent Health: Unveiling Global Trends Across 41 Countries in Psychological and Somatic Complaints (1994-2022).

Objectives: This study examined (non-)monotonic time trends in psychological and somatic complaints among adolescents, along with gender differences.

Methods: Repeated cross-sectional Health Behaviour in School-aged Children (HBSC) data from 1994 to 2022 covering 15-year-old adolescents from 41 countries (N = 470,797) were analysed. Three polynomial logistic regression models (linear, quadratic, cubic) were tested for best fit, including separate analyses by gender and health complaints dimension.

In Vitro Susceptibility of Clinical and Carrier Strains of to STAFAL Phage Preparation.

The treatment of infections caused by is currently complicated by the increasing number of strains resistant to antimicrobial agents. One promising way to solve this problem is phage therapy. Due to the lack of data on the effectiveness and safety of phage preparations, STAFAL is the only registered phage preparation for the treatment of infectious diseases in the Slovak Republic and the entire European Union.

Association of Sympathovagal Imbalance with Increased Inflammation and Impaired Adaptive Immunity in Bladder Cancer Patients.

Stress responses can impact bladder cancer (BC) outcomes via immune-inflammatory pathway modulation. This study explores heart rate variability (HRV) associations with serum immune-inflammatory biomarkers, blood count inflammatory markers, and psychosocial self-report measures in patients versus healthy controls. The TREM-1 and TREM-2 expressions on peripheral blood monocytes were analysed via flow cytometry; serum inflammatory biomarkers by ELISA; HRV (5-min ECG) pre-tumour resection; blood counts by haematology analyser; and psychosocial factors by validated questionnaires.

Comparative Study of Water and Milk Kefir Grains as Biopolymeric Adsorbents for Copper(II) and Arsenic(V) Removal from Aqueous Solutions.

This study investigates the biosorption capabilities of kefir grains, a polysaccharide-based byproduct of the fermentation process, for removing copper(II) and arsenic(V) from contaminated water. Unlike traditional heavy-metal removal methods, which are typically expensive and involve environmentally harmful chemicals, biopolymeric materials such as kefir grains provide a sustainable and cost-effective alternative for adsorbing hazardous inorganic pollutants from aqueous solutions. Our experimental results revealed significant differences in the sorption capacities of two types of kefir grains.

Keto Analogues in Patients with Chronic Kidney Disease with or Without Kidney Transplantation.

Keto analogues in combination with a (very) low-protein diet significantly reduces the progression to end-stage kidney disease. The question of their benefit and safety for kidney transplant recipients remains. This study aimed to show the renoprotective effect and safety of the use of this method in patients with chronic kidney disease and a kidney transplantation.

Pneumoperitoneum after placement of the temporary pacing wires: transverse colon injury at the base of a diverticulum.

We present the successful management of a patient presenting with pneumo-peritoneum early after surgery due to transvere colon injury after placement of the temporary pacing wires. The patient was asymptomatic, underwent computed tomography, the temporary pacing wires were removed and he was managed conservatively.

Late Bedtime from the Perspective of Adolescents: A Qualitative Study.

Purpose: Later sleep timing is a key determinant of reduced sleep duration and quality in adolescents and is associated with negative mental and physical outcomes. However, little is known about adolescents' views on late bedtime. The study's purpose is to explore adolescents' perspectives on why they go to sleep late during school nights and what would help them to go to bed earlier.

Wound healing: insights into autoimmunity, ageing, and cancer ecosystems through inflammation and IL-6 modulation.

Wound healing represents a complex and evolutionarily conserved process across vertebrates, encompassing a series of life-rescuing events. The healing process runs in three main phases: inflammation, proliferation, and maturation/remodelling. While acute inflammation is indispensable for cleansing the wound, removing infection, and eliminating dead tissue characterised by the prevalence of neutrophils, the proliferation phase is characterised by transition into the inflammatory cell profile, shifting towards the prevalence of macrophages.

Morphological changes in cerebrospinal fluid production.

The ventricular system and subarachnoid space are filled with cerebrospinal fluid, which plays a key role in the nervous system. This fluid is produced by the choroid plexus, an organ rich in ion transporters that precisely control the transport of specific ions into the cerebrospinal fluid thanks to tight junctions between the plexus cells; these prevent the passage of substances other than the transporters, thus allowing for precise control of the fluid composition. Cerebrospinal fluid production is based on a network of interrelationships between specific ion flows enabled by the numerous transporters.

Promoting Prevention and Targeting Remission of Asthma: A European Forum for Research and Education in Allergy and Airway Diseases Consensus Statement on Raising the Bar in Asthma Care.

Asthma is a common multifaceted respiratory disease with a major impact on quality of life. Despite increased insights into mechanisms underlying various asthma phenotypes and endotypes and the availability of targeted biologic treatment options, the disease remains uncontrolled in a substantial proportion of patients with risk of exacerbations, requiring systemic corticosteroids, and with progressive disease. Current international guidelines advocate a personalized management approach to patients with uncontrolled severe asthma.

-related disorder in 87 adults: Natural history and self-sustainability.

Purpose: is one of the most frequently mutated genes in intellectual disability cohorts. Thus, far few adult-aged patients with -related disorder have been described, which limits our understanding of the disease's natural history and our ability to counsel patients and their families.

Methods: Data on patients aged 18+ years with -related disorder were collected through an online questionnaire completed by clinicians and parents.

Determination of activities of Pb in Slovak tobacco and cigarettes: a study on radiological risks.

This study investigates the Pb activity concentrations in tobacco and cigarettes available in Slovakia, utilizing two specific extraction methods including the Sr Resin sorbent used in extraction chromatography, and the AnaLig Sr01 sorbent, which operates based on molecular recognition principles. The findings revealed significant variations in Pb activity concentrations, with concentrations ranging from 13.3 to 33.

Time-restricted feeding does not improve daily rhythms in locomotion and drinking disrupted by artificial light at night.

Exposure to artificial light at night (ALAN) disrupts natural darkness and desynchronizes daily rhythms in physiological processes and behavior. Previously, in rats, we have shown that dim ALAN disturbed the central circadian control and the temporal organization of behavior, and hormonal and metabolic pathways. The measurements of undisturbed daily behavioral (locomotor activity, feeding and drinking) patterns revealed reduced amplitudes and a transitory activity peak in the middle of the light (i.

Practical application of PMA-qPCR assay for determination of viable cells of inter-species biofilm of .

Determining the number of viable cells by calculating colony-forming units is time-consuming. The evaluation of mixed biofilms consisting of different species is particularly problematic. Therefore, the aim of this study was to optimize a molecular method-propidium monoazide quantitative polymerase chain reaction (PMA-qPCR)-for accurate and consistent differentiation between living and dead cells.