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Pulmonary renal syndrome: A case report of diffuse alveolar hemorrhage in association with ANCA negative pauci-immune glomerulonephritis.

Medicine (Baltimore)

June 2018

Division of Pulmonary and Critical Care Medicine Department of Medicine, Bronx Care Health System, Bronx, NY Department of Pathology, College of Physicians and Surgeons, Columbia University Affiliated with Icahn School of Medicine at Mount Sinai, New York, NY.

Rationale: Pulmonary renal syndrome (PRS) is a term most commonly used to describe a combination of glomerulonephritis and pulmonary hemorrhage as a manifestation of a multisystem autoimmune disease. It is usually associated with ANCA vasculitis and anti-GBM disease. Diffuse alveolar hemorrhage in a patient with ANCA and anti-GBM negative pauci-immune glomerulonephritis is rare and optimal management is unknown.

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