1 results match your criteria: "Colorado 80045 USA. cThe Ragon Institute of MGH[Affiliation]"

Distinctive features of CD4+ T cell dysfunction in chronic viral infections.

Curr Opin HIV AIDS

September 2014

aDepartement of Medicine and Centre de Recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM), University of Montreal, Montréal, Quebec, Canada bUniversity of Colorado, Research Complex 2, room 10007 (B164), 12700 E 19th Ave, Aurora, Colorado 80045 USA. cThe Ragon Institute of MGH, MIT and Harvard, Cambridge, Massachusetts, USA.

Purpose Of Review: To describe recent advances in the understanding of virus-specific CD4 T cell dysfunction in chronic viral infections, with an emphasis on HIV disease. We highlight features that are distinctive for CD4 T cells, as opposed to their CD8 T cell counterparts.

Recent Findings: CD4 T cell activation and differentiation are tightly controlled.

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