480 results match your criteria: "Cologne-Merheim Medical Center[Affiliation]"

Background: The German Infection Protection Act and KRINKO recommend nominating one authorized medical specialist in every medical department as an infection prevention link physician (PLP). Detailed evidence on the contribution of PLPs to reducing infection rates is not available in Germany.

Aim: The "HygArzt"-study investigated whether, and to what extent, a PLP in orthopaedics/trauma surgery is able to improve hand hygiene adherence (HHA), process steps of dressing change, nosocomial infection (NI) and surgical site infection (SSI) rates by implementing an infection prevention bundle (IPB).

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: The insertion of chest drains (CD) in trauma patients is a lifesaving, albeit high-risk intervention. Safe insertion of CD in settings where aids like ultrasound are not available relies on a landmark technique defining the so-called triangle of safety. The inferior margin of this triangle is identified by nipple height, which is thought to correspond to the fifth intercostal space (ICS).

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Purpose: To clarify whether different methods of quantifying lateral femoral condyle (LFC) bone morphology as risk factors for anterior cruciate ligament (ACL) injury on lateral radiographs should be considered as individual risk factors and to assess inter- and intraobserver reliability.

Methods: We retrospectively reviewed 487 patients undergoing primary ACL reconstruction at our institution. Routine lateral radiographs of the injured knees were utilized to measure the following parameters: LFC ratio (LFCR), height of LFC to anteroposterior diameter ratio (HAPR), femur tibia size ratio (FTSR), tibia to posterior femoral condyle ratio (TPFCR) and Porto ratios (XY/AB; B/AB; B/XY).

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Article Synopsis
  • - This study explores how machine learning can predict whether individuals with traumatic brain injury (TBI) will return to work one year after their injury, using data collected from 586 hospitalized patients across Europe.
  • - By analyzing hospital stay and follow-up data, the researchers found that including follow-up information significantly improved prediction accuracy, going from around 81% to 88%.
  • - The final model, which included five key predictors, achieved 90% accuracy and can help clinicians set realistic goals and tailor interventions for TBI patients, enhancing their chances of returning to work.
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Lived experiences of working-age polytrauma patients in Germany - A qualitative Analysis.

Injury

January 2025

Academy for Traumatology (AUC) @ German Society of Traumatology, Straße des 17, Juni 106-108, Berlin, Germany.

Article Synopsis
  • Survivors of major trauma face various challenges affecting their physical, mental, and social well-being, ultimately impacting their quality of life, which the study investigates within the German healthcare system.
  • The research involved interviews with nine trauma survivors, highlighting key issues like poor communication between healthcare providers and the need for dedicated support contacts during recovery.
  • Findings emphasize the importance of social support from networks, including employers, as crucial for emotional healing and successful reintegration into work and life, with mobility playing a key role in enhancing overall quality of life.
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Purpose: Addressing grade 2 and 3 medial-sided instabilities during anterior cruciate ligament (ACL) reconstruction is crucial to reduce the risk of ACL graft failure. This study introduced a minimally invasive, medial collateral ligament (MCL) augmentation technique using a peroneus longus split tendon autograft, which was fixed to the femoral deep MCL insertion and tibial superficial MCL insertion.

Methods: This prospective, longitudinal, single-centre case series included patients who underwent MCL augmentation concurrent with primary or revision ACL reconstruction due to anteromedial instability.

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Article Synopsis
  • The study investigates the relationship between femoroacetabular morphology and the mechanisms of traumatic posterior hip dislocations in adults, focusing on differentiating between high-energy, sports-related, and low-energy trauma.
  • A total of 141 patients with dislocations were compared to a control group, utilizing CT scans to measure various anatomical angles related to hip structure and injury.
  • Findings revealed that most dislocations were due to high-energy events, with specific morphologies (like acetabular retroversion) linked to different trauma mechanisms, while low-energy impacts showed similar anatomy to the control group.
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Comparison of the European Foot and Ankle Score (EFAS) and the Self-Reported Foot and Ankle Score (SEFAS) in patients with foot and ankle surgery.

Arch Orthop Trauma Surg

November 2024

Department of Orthopedic and Trauma Surgery, Member Faculty of Health Witten/ /Herdecke University, St. Elisabeth-Hospital Herten, Im Schlosspark 12, 45699, Herten, Germany.

Background: The European Foot and Ankle Score EFAS and the Self-reported Foot and Ankle Score SEFAS are two Patient Reported Outcome Measures (PROMs) used in foot and ankle surgery. The EFAS has been published in recent years, while the SEFAS is a validated questionnaire based on the New Zealand total ankle questionnaire.

Methods: We compared the EFAS to the SEFAS, Short Form 36 (SF-36) and Numeric Rating Scale (NRS) regarding reliability and validity based on the results of 126 patients undergoing foot and ankle surgery in a single center.

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Article Synopsis
  • Nonoperative management (NOM) is increasingly used for blunt splenic injuries (BSIs) in Germany, showing high success rates even in severe cases, with guidelines supporting this practice.
  • A study analyzed data from 2,782 patients with BSIs, revealing that 57.5% received NOM while angioembolization (ANGIO) was used in only 1.0% of cases, mainly for less severe injuries.
  • The findings suggest a disconnect between clinical practice and guidelines, as more severe injuries typically led to splenectomy instead of ANGIO, highlighting the potential need for improved local treatment protocols.
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Advances in Modern Microsurgery.

J Clin Med

September 2024

Clinic of Plastic and Aesthetic Surgery, Helios Hospital Berlin-Buch, Schwanebecker Chaussee 50, 13125 Berlin, Germany.

Article Synopsis
  • Microsurgery utilizes optical magnification and specialized instruments for operating on small structures, playing a crucial role in procedures like tissue transfer and nerve reconstruction in plastic surgery.
  • A comprehensive literature search was conducted to identify relevant studies and advancements in microsurgery, focusing on its historical context and current applications.
  • Recent innovations, including robotic-assisted surgery and advanced imaging techniques, have greatly enhanced surgical precision and outcomes, with future developments in AI and robotics expected to further improve microsurgical practices.
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Treatment and clinical outcome in patients with femoral head fractures: a long-term follow-up.

Arch Orthop Trauma Surg

September 2024

Department of Trauma and Orthopedic Surgery, Cologne Merheim Medical Center, Witten/Herdecke University, Cologne, Germany.

Introduction: A femoral head fracture (Pipkin fracture) is a rare but severe injury. The optimal treatment is controversial, and there is a lack of research focusing on treatment strategies. The study aimed to analyze the treatment strategies in comparison to the outcome in patients after traumatic hip joint dislocation (THD) with concomitant femoral head fractures.

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Article Synopsis
  • This study evaluated the effectiveness of two ACL restoration techniques—repair with internal bracing (ACLIB) and reconstruction with autograft (ACLR)—in treating acute knee dislocations, highlighting ACLR as offering better stability, especially at 12 months post-surgery.
  • A total of 20 patients were included, and outcomes were assessed through patient-reported measurements and stress tests, showing ACLR had significantly lower tibial translation compared to ACLIB at the 24-month follow-up.
  • Both techniques produced good patient satisfaction scores, but knee stiffness was a common complication, which was effectively treated with early arthroscopic procedures.
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Is It Possible to Monitor the Safest Time to Perform Secondary Surgery on Free Flaps? A Clinical Evaluation of the Tewameter.

Medicina (Kaunas)

August 2024

Clinic for Plastic and Hand Surgery, Burn Care Center, Cologne Merheim Medical Center (CMMC), University of Witten/Herdecke, 51109 Cologne, Germany.

: Postoperative monitoring, following free flap surgery, plays a crucial role in ensuring the survival of the flap. However, in microsurgery, not only the immediate postoperative monitoring period but also the choice of the right time for secondary surgeries is crucial for the free flap survival. There is no clear consensus concerning the right choice of timing for secondary surgery.

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Background: Trauma induced coagulopathy remains to be an important cause of high transfusion requirements and mortality and shock induced endotheliopathy (SHINE) has been implicated.

Methods: European multicenter observational study of adult trauma patients with injury severity score ≥ 16 arriving within 2 h from injury to the trauma centers. Admission blood samples obtained were used for analysis of the SHINE biomarkers (syndecan-1, soluble thrombomodulin, adrenaline) and extensive analysis of coagulation, -and fibrinolytic factors together with collection of clinical data.

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Treatment of anastomotic leak in colorectal surgery by endoluminal vacuum therapy with the VACStent avoiding a stoma - a pilot study.

Langenbecks Arch Surg

July 2024

Department of Abdominal, Tumor, Transplant and Vascular Surgery, Cologne-Merheim Medical Center, Witten/Herdecke University, Ostmerheimer Strasse 200, D-51109, Cologne, Germany.

Purpose: Anastomotic leak (AL) represents the most relevant and devastating complication in colorectal surgery. Endoscopic vacuum therapy (EVT) using the VACStent is regarded as a significant improvement in the treatment of upper gastrointestinal wall defects. The innovative concept of the VACStent was transferred to the lower GI tract, gaining initial experience by investigating safety and efficacy in 12 patients undergoing colorectal resections.

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Early Point-of-Care Thromboelastometry Reduces Mortality in Patients with Severe Trauma and Risk of Transfusion: An Analysis Based on the TraumaRegister DGU.

J Clin Med

July 2024

Committee on Emergency Medicine, Intensive Care and Trauma Management (Sektion NIS) of the German Trauma Society (DGU®), 10623 Berlin, Germany.

Thromboelastometry like ROTEM is a point-of-care method used to assess the coagulation status of patients in a rapid manner being particularly useful in critical care settings, such as trauma, where quick and accurate assessment of coagulation can guide timely and appropriate treatment. Currently, this method is not yet comprehensively available with sparse data on its effectiveness in resuscitation rooms. The aim of this study was to assess the effect of early thromboelastometry on the probability of mass transfusions and mortality of severely injured patients.

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VacStent as an Innovative Approach in the Treatment of Anastomotic Insufficiencies and Leakages in the Gastrointestinal Tract-Review and Outlook.

Life (Basel)

June 2024

Center for Interdisciplinary Visceral Medicine, Department of Abdominal, Tumor, Transplant and Vascular Surgery, Cologne-Merheim Medical Center, Witten/Herdecke University, 51109 Cologne, Germany.

Anastomotic insufficiencies are severe complications of abdominal surgery, often leading to prolonged hospitalization, serious tissue inflammation, and even sepsis, along with the need for recurrent surgery. Current non-surgical treatments such as self-expanding metal stents (SEMSs) and endoscopic vacuum therapy (EVT) have limitations, including stent migration or perforation. This review evaluates the effectiveness of the VacStent GI (Möller Medical GmbH, Fulda, Germany), a novel medical device combining SEMS and negative-pressure wound therapy in treating gastrointestinal leaks.

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Background: Studies prospectively monitoring donor-specific antibodies (dnDSAs) and their clinical impact are sparse. This substudy of ATHENA was initiated to evaluate the effect of everolimus (EVR) or mycophenolic acid (MPA) in combination with reduced calcineurin inhibitor (CNI, tacrolimus [TAC] or cyclosporine [CsA]) on the formation of human leukocyte antibodies (HLA), including dnDSA, and the impact on clinical outcomes in kidney transplant (KTx) recipients.

Methods: All eligible patients were randomized 1:1:1 to receive either EVR + TAC, EVR + CsA or MPA + TAC, with basiliximab induction plus steroids after transplantation up to Month 12.

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Article Synopsis
  • The REVERXaL study investigates the characteristics and management of hospitalized patients who experience major bleeds related to factor Xa inhibitors (FXai), a new class of anticoagulants.
  • It includes two cohorts: a historical cohort analyzing past patient data and a prospective cohort that evaluates current treatment and patient-reported outcomes over three months.
  • The study aims to provide valuable information on treatment approaches and patient outcomes, potentially improving clinical practices for managing FXai-associated major bleeds.
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Implementation of health-related quality of life in the German TraumaRegister DGU® - first results of a pilot study.

Health Qual Life Outcomes

June 2024

Department of Orthopaedics and Traumatology, University Hospital and Medical Faculty, Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany.

Background: Approximately 30,000 people are affected by severe injuries in Germany each year. Continuous progress in prehospital and hospital care has significantly reduced the mortality of polytrauma patients. With increasing survival rates, the functional outcome, health-related quality (hrQoL) of life and ability to work are now gaining importance.

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Direct contact and very rapid valgus distortion characterise the injury mechanism of anterior cruciate ligament ruptures in judo.

Knee Surg Sports Traumatol Arthrosc

November 2024

Department of Orthopaedic Surgery, Trauma Surgery, and Sports Medicine, Cologne Merheim Medical Center, Witten/Herdecke University, Cologne, Germany.

Purpose: To analyse anterior cruciate ligament (ACL) rupture (ACLR) injury mechanisms in competitive judo using systematic video analysis, focusing on contact situations and biomechanics.

Methods: Seventeen videos of judo competitions wherein athletes developed ACLRs were included and retrospectively evaluated by five analysts. In all videos, the moment of initial contact and the index frame were defined.

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App-based analysis of the femoral tunnel position in ACL reconstruction using the quadrant method.

Arch Orthop Trauma Surg

July 2024

Department of Trauma Surgery, Orthopaedics and Sports Traumatology, BG Klinikum Hamburg, Bergedorfer Strasse 10, 21033, Hamburg, Germany.

Purpose: The purpose of this study was to examine the intra- and interobserver variability of an app-based analysis of the femoral tunnel position using the quadrant method in primary anterior cruciate ligament reconstruction.

Materials And Methods: Between 12/2020 und 12/2021 50 patients who underwent primary anterior cruciate ligament reconstruction were included in this retrospective study. Intraoperative strictly lateral fluoroscopic images of the knee with marked femoral tunnel were analyzed by four observers using the quadrant method.

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Purpose: Arthroscopic reconstruction techniques for higher-grade posterolateral corner (PLC) injuries (Fanelli Type B, PoLIS LI-B) have not yet been validated in clinical studies. The open reconstruction technique described by Arciero is well-established and showed good restoration of joint stability in previous studies. This study aimed to compare clinical outcomes of this established open surgery technique to a newly developed arthroscopic technique in a prospective randomized clinical trial.

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High-Intensity Blue Light (450-460 nm) Phototherapy for -Infected Wounds.

Photobiomodul Photomed Laser Surg

May 2024

Institute for Research in Operative Medicine (IFOM), Cologne-Merheim Medical Center, Witten/Herdecke University, Cologne, Germany.

Nosocomial wound infection with (PA) is a serious complication often responsible for the septic mortality of burn patients. High-intensity antimicrobial blue light (aBL) treatment may represent an alternative therapy for PA infections and will be investigated in this study. Antibacterial effects of a light-emitting diode array (450-460 nm; 300 mW/cm; 15/30 min; 270/540 J/cm) against PA were determined by suspension assay, biofilm assay, and a human skin wound model and compared with 15-min topically applied 3% citric acid (CA) and wound irrigation solution (Prontosan; PRT).

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