4 results match your criteria: "College of Stomatology Shanghai Jiao Tong University School of Medicine[Affiliation]"
Integrating clinical and genomic landscape analysis of perineural invasion identify ACTA1 as an oncogene for oral squamous cell carcinoma.
Front Cell Dev Biol
October 2024
Central Laboratory, Nanjing Stomatological Hospital, Medical School of Nanjing University, Nanjing, Jiangsu, China.
Article Synopsis
- Perineural invasion (PNI) in oral squamous cell carcinoma (OSCC) is linked to advanced tumors and poorer patient outcomes, but the molecular mechanisms and clinical implications are still being studied.
- A study analyzed 279 OSCC samples, finding that PNI is associated with changes in immune cell composition, specifically lower T follicular helper cells and higher M2 macrophages, indicating a potential environment for immune evasion.
- The identified protein Actin α1 (ACTA1) was significantly upregulated in PNI cases and may indicate a sensitivity to immunotherapy, suggesting that patients with high ACTA1 could benefit from treatments targeting cytotoxic T cells.
Computed tomographic features of adenoid cystic carcinoma in the palate.
Cancer Imaging
January 2019
Department of Oral and Maxillofacial-Head and Neck Oncology, Ninth Peoples Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, No. 639 Zhizaoju Road, Shanghai, 200011, China.
Background: To evaluate the computed tomographic features and create a prediction model for clinical diagnosis of adenoid cystic carcinoma (ACC) in the palate with intact mucosa.
Methods: From March 2016 to May 2018, 102 patients with palatal tumors and intact mucosa, including 28 patients with a pathological diagnosis of ACC after surgery, were enrolled in this study. The patients' clinical symptoms, computed tomographic features and pathological diagnoses were recorded and analyzed.
Topical Timolol Vs. Oral Propranolol for the Treatment of Superficial Infantile Hemangiomas.
Front Oncol
December 2018
Department of Oral and Maxillofacial Surgery, Shanghai Ninth People's Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Infantile hemangiomas (IHs) are the most common vascular tumors of infancy. Oral propranolol has achieved great success in treating IHs since 2008. To minimize the systemic side events caused by oral administration of propranolol, topical timolol started to be applied in the treatment of IHs, especially for superficial lesions.
View Article and Find Full Text PDFInterdisciplinary Surgical Management of Multiple Facial Fractures With Image-Guided Navigation.
J Oral Maxillofac Surg
September 2015
Associate Professor, Department of Oral and Maxillofacial Surgery, Ninth People's Hospital, College of Stomatology Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Article Synopsis
- The study evaluated the effectiveness of using image-guided surgical navigation for managing multiple facial fractures in 36 patients from 2011 to 2014.
- Through virtual 3D modeling and interdisciplinary collaboration, the surgeries were performed with precision, showing a systematic error of just 1 mm during navigation.
- Results indicated that all patients healed well without serious complications, and the surgical outcomes demonstrated an accurate concordance with preoperative plans, supporting the method as a valuable strategy for complex facial fracture surgeries.