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Article Synopsis
- Development of a new immunotherapy approach for breast cancer focuses on overcoming issues with antigen presentation to T cells, which is critical for successful treatment.
- The strategy combines immune cell infiltration, immunogenic cell death, and dendritic cell maturation using a smart nanosystem that releases multiple therapeutic agents directly in the tumor microenvironment.
- Local injection of this nanoparticle leads to significant tumor regression by enhancing immune cell activity and targeting specific tumor tissues, indicating its potential as an effective clinical treatment for breast cancer.