6 results match your criteria: "College of Nursing at Augusta University[Affiliation]"
Risk factors and mortality in patients with listeriosis and end-stage renal disease.
Am J Med Sci
October 2023
Department of Medicine, Medical College of Georgia at Augusta University, Augusta, GA, USA; Charlie Norwood VA Medical Center, Augusta, GA, USA. Electronic address:
Article Synopsis
- End-stage renal disease (ESRD) patients are at a higher risk for serious infections, particularly listeriosis, due to their immunocompromised status.
- A study analyzing data from over a million ESRD patients found that listeriosis is significantly associated with several risk factors, such as cardiovascular disease and diabetes.
- The research indicates that listeriosis is more common in ESRD patients than in the general population and is linked to increased mortality, highlighting the need for careful diagnosis in this vulnerable group.
Hashimoto's thyroiditis and renal transplant rejection.
J Endocrinol Invest
October 2023
Medical College of Georgia at Augusta University, 1120 15th Street, Augusta, GA, 30912, USA.
Purpose: Hashimoto's thyroiditis (HT) is a common autoimmune thyroid disorder that can disrupt thyroid function and homeostasis. As HT results from a dysregulated immune system, we hypothesized that these patients might be more susceptible to transplant failure; however, literature on this association is limited. The purpose of this study is to examine the association of HT with the risk of renal transplant failure.
View Article and Find Full Text PDFCutaneous squamous cell carcinoma and mortality in end-stage renal disease.
Am J Med Sci
March 2023
Medical College of Georgia at Augusta University, Augusta, GA, United States; Charlie Norwood VA Medical Center, Augusta, GA, United States. Electronic address:
Background: In the general population, cutaneous squamous cell carcinoma (cSCC) is associated with increased all-cause mortality. Transplant patients have been shown to have an increased risk of developing cSCC, and their cSCC is associated with an increased risk for mortality. In end-stage renal disease (ESRD) patients, there is extensive mortality and immune dysfunction.
View Article and Find Full Text PDFRole of prostaglandin D2 receptors in the pathogenesis of abdominal aortic aneurysm formation.
Clin Sci (Lond)
March 2022
Department of Medicine, College of Nursing at Augusta University, Augusta, GA, U.S.A.
Article Synopsis
- Prostaglandin D2 (PGD2) plays a role in promoting inflammation and may contribute to vascular diseases like abdominal aortic aneurysm (AAA), but the involvement of its receptors, DP1 and DP2, hasn't been thoroughly studied in AAA.
- In experiments using mice models, researchers found that DP1-deficient mice were protected from AAA formation, showing reduced inflammation and matrix metallopeptidase (MMP) activity.
- The study suggests that targeting DP receptors with specific inhibitors could be a potential therapeutic approach to treat AAA, similar to their use in treating allergic and lung diseases.
Profiling of Histone Modifications Reveals Epigenomic Dynamics During Abdominal Aortic Aneurysm Formation in Mouse Models.
Front Cardiovasc Med
October 2020
Departments of Medicine, College of Nursing at Augusta University, Augusta, GA, United States.
Abdominal aortic aneurysms (AAA) are characterized by localized inflammation, extracellular matrix degradation, and apoptosis of smooth muscle cells, which together lead to progressive and irreversible aortic dilation. Major risk factors for AAA include smoking and aging, both of which prominently alter gene expression via epigenetic mechanisms, including histone methylation (me) and acetylation (ac).However, little is known about epigenomic dynamics during AAA formation.
View Article and Find Full Text PDFPostoperative nausea and vomiting (PONV) continue to be among the most undesirable and distressing complications following general anesthesia, affecting 20% to 30% of all surgical patients and up to 70% of patients with multiple known risk factors. The purpose of this study was to reexamine the effectiveness of metoclopramide in the prevention of PONV when stratified by PONV risk scores. Secondary data from 2,116 adult ambulatory surgical patients were analyzed.
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