Exploring the presence and roles of humility when experiencing situations of uncertainty.

Background: Uncertainty is a pervasive challenge in clinical practice. Whereas the importance of humility in navigating uncertainty has been discussed, empirical research on how humility is practiced or expressed (i.e.

Exploring the Psychosocial Domain of the Social Determinants of Learning™ Framework: Predictors of Perceived Stress and Resilience in Prenursing Students.

Background: The Social Determinants of Learning™ framework can be used to conceptualize the influence of psychosocial health among students applying to nursing programs. Little is known about variables that may influence psychosocial health in these students.

Purpose: To describe demographic and mental health variables that predict perceived stress and resilience levels in accelerated online prenursing students.

Prolonged nightly fasting in older adults with memory decline: A single-group pilot study exploring changes in cognitive function and cardiometabolic risk factors.

Introduction: Older age significantly increases risk for cognitive decline. A growing number of older adults (≥ 65 years) experience cognitive decline that compromises immediate and/or long-term health. Interventions to mitigate cognitive decline are greatly needed.

Multidimensional sleep health and cognitive function across adulthood.

Study Objectives: Sleep is essential for proper function of the mind and body. Studies report the effect of sleep problems on cognition but focus on only a single or limited number of sleep indicators or on clinical populations (e.g.

Health impacts of a remotely delivered prolonged nightly fasting intervention in stressed adults with memory decline and obesity: A nationwide randomized controlled pilot trial.

Objective/goals: Cognitive decline is intricately linked to various factors such as obesity, stress, poor sleep, and circadian rhythm misalignment, which are interrelated in their impact on cognitive health. Irregular food-intake timing further compounds these issues. The practice of prolonged nightly fasting (PNF) may help synchronize food intake with circadian rhythms, potentially mitigating adverse effects of cognitive decline and associated factors.

HIV Vulnerability Typologies Among Adolescent Girls and Young Women in Lesotho: A Population-Based, Cross-Sectional, Latent Class Analysis.

Adolescent girls and young women ages 15-29 years (AGYW) living in Lesotho experience a disproportionate HIV burden. Using a household-based national survey in Lesotho, we conducted a three-step latent class analysis to identify typologies of AGYW most vulnerable to HIV infection. We first classified AGYW into HIV vulnerability groups based on self-reported sexual behaviors, then identified associations between typology and HIV diagnosis.

Pilot Testing Digital Stories to Influence College Men's Intentions to Vaccinate Against HPV.

College men are among those least likely to be vaccinated against the human papillomavirus (HPV). Viewing digital stories from other college men who were vaccinated against HPV as young adults may help influence them to seek the vaccine. Guided by the Theory of Planned Behavior, this research reports on the creation and pilot testing of digital stories to increase college men's intentions to vaccinate against HPV.

The association of high-density lipoprotein cargo proteins with brain volume in older adults in the Atherosclerosis Risk in Communities (ARIC).

Background: High-density lipoprotein (HDL) modulates the blood-brain barrier and cerebrovascular integrity, likely influencing the risk of Alzheimer's disease (AD), neurodegeneration, and cognitive decline.

Objective: This study aims to identify HDL protein cargo associated with brain amyloid deposition and brain volume in regions vulnerable to AD pathology in older adults.

Methods: HDL was separated from the plasma of 65 non-demented participants of the Atherosclerosis Risk in Communities (ARIC) study using a fast protein liquid chromatography method.

Parenting Concerns, Psychological Distress, and Relationship Adjustment Among Patients With Cancer and Their Partners: A Longitudinal Study.

Objective: Studies have found that cancer patients with dependent children exhibit high symptoms of anxiety, depression, and worry. Patients' parenting concerns can negatively impact their own and their family's adjustment to the cancer experience. However, relatively little is known about parenting concerns of partners of cancer patients, or associations between parenting concerns and couples' relationship adjustment.

Community Engagement in the BE SAGE Project: Reducing COVID-19 in Hispanic and Low-Income Preschoolers via Testing and Open-Air Garden-Based Education.

Objective: Back to Early Care and Education Safely With Sustainability via Active Garden Education (BE SAGE) involved COVID-19 testing and a free garden-based physical activity and nutrition program at early care and education centers with primarily Hispanic/Latino enrollment. This article describes the project community engagement plan, process, and outcomes focusing on deliberate and intentional staffing, an extensive online presence, and focused outreach.

Methods: BE SAGE purposefully hired bilingual (English/Spanish) and bicultural staff; developed and maintained a large bilingual online presence (website, newsletters, social media), and fostered community partnerships with community health workers (CHWs) and dedicated staff.

Preparing to intervene in intimate partner violence: An interprofessional safety planning and assessment simulation.

The healthcare system is often the point where intimate partner violence (IPV) can be identified and where intervention strategies are initiated. Healthcare workers often operate in silos; therefore, timely and appropriate intervention depends on effective interdisciplinary communication and teamwork. Interprofessional education initiatives are one method for promoting interdisciplinary cooperation.

Interprofessional Education for Domestic Violence Safety Planning in Nursing and Social Work: A Scoping Review.

Rationale: Nurses and social workers in healthcare settings are positioned to identify abuse and contribute to improving the wellbeing of victims and their family members by screening for, providing safety education about, and reporting abuse when required by law.

Objective: The review aims to assess the current state of the simulation education for addressing the needs of domestic violence (DV) survivors to screen, assess, and intervene in DV cases in healthcare settings.

Method: A scoping review to map the peer-reviewed evidence on interprofessional education (IPE) was conducted by means of automated database search for nursing and social work students.

Recommendations to reduce and prevent negative health outcomes and healthcare costs among night shift nurses: An AAN consensus paper.

A growing body of evidence demonstrates occupational night shift hazards. Decades of research point to health risks for nurses contributing to chronic diseases, including diabetes, cardiovascular disease, cognitive/mental health, and cancers-all associated with earlier mortality. Patient safety, recruitment and retention of quality nursing workforce, and related costs are important concerns associated with night shift work.

In Obesity, Esophagogastric Junction Fat Impairs Esophageal Barrier Function and Dilates Intercellular Spaces via Hypoxia-Inducible Factor 2α.

Background & Aims: Dilated intercellular space in esophageal epithelium, a sign of impaired barrier function, is a characteristic finding of gastroesophageal reflux disease that is also found in obese patients without gastroesophageal reflux disease. We explored molecular mechanisms whereby adipose tissue products might impair esophageal barrier integrity.

Methods: Cultures of visceral fat obtained during foregut surgery from obese and nonobese patients were established.

Challenges and barriers to WIC participation vary by participation status and language: Findings from focus groups in Missouri.

The Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) is one of the largest federal food and nutrition program serving women and young children and has a low coverage rate of about 50 percent. There is no peer-reviewed article that compares maternal perceptions of challenges and barriers to WIC participation by language and participation status. We compare challenges and barriers faced by English-speaking mothers to those faced by Spanish-speaking mothers to enrollment and retention in WIC within each group: current participants (n = 43), prior participants (dropouts; n = 27), and eligible non-participants (n = 18), using focus groups we conducted in Missouri in 2021-2023.

Transitions to Nursing Homes among Residents of Assisted Living and Community-Dwelling Home Care Recipients.

Objectives: To examine transitions to a nursing home among residents of assisted living relative to community-dwelling home care recipients.

Design: Population-based retrospective cohort study emulating a target trial.

Setting And Participants: Linked, individual-level health system data were obtained from older adults (aged ≥65 years) who made an incident application for a bed in a nursing home in Ontario, Canada, between April 1, 2014, and March 31, 2019, and were followed until December 31, 2019.

Designing work for healthy sleep: A multidimensional, latent transition approach to employee sleep health.

Healthy sleep is essential to employee well-being and productivity, but many modern workers do not obtain adequate sleep. Are technology-related changes to job design (i.e.

The Effects of Experimental Sleep Extension in Middle-to-Older-Aged Healthy Sleepers.

 To determine the feasibility for middle-aged and older adults to extend their time in bed by 2 h per night for 3 consecutive weeks. Other aims were to examine the effects of sleep extension on mood, cognitive performance, and cardiovascular health.  Ten healthy middle-aged to older adults (9 women;  = 65.

ALDH3A1-mediated detoxification of reactive aldehydes contributes to distinct muscle responses to denervation and Amyotrophic Lateral Sclerosis progression.

Different muscles exhibit varied susceptibility to degeneration in Amyotrophic Lateral Sclerosis (ALS), a fatal neuromuscular disorder. Extraocular muscles (EOMs) are particularly resistant to ALS progression and exploring the underlying molecular nature may deliver great therapeutic value. Reactive aldehyde 4-hydroxynonenal (HNE) is implicated in ALS pathogenesis and ALDH3A1 is an inactivation-resistant intracellular detoxifier of 4-HNE protecting eyes against UV-induced oxidative stress.

Characterizing Drug use Typologies and Their Association with Sexual Risk Behaviors: A Latent Class Analysis Among Men who have Sex with Men in Mexico.

Introduction: Drug use behaviors are closely associated with increased risk for HIV and other STIs among men who have sex with men (MSM) globally. Less is known about the drug use characteristics and their association with HIV/STI risk among MSM in Mexico, who have 13 times higher risk of acquiring HIV than the general population. We characterized distinct classes of drug use behaviors among a nationwide sample of MSM in Mexico and tested their associations with HIV risk behaviors.

Impact of Childhood Adversity on Late-Life Cognition in Older Puerto Rican Adults.

Objectives: This study examined the association between childhood adversity and late-life cognitive outcomes among older Puerto Rican adults.

Methods: Data were from the PREHCO study, a population-based cohort of 3,713 older Puerto Rican adults (mean age 72.5 years; 60% female).

Experiential diversity theory of adult development and aging in daily life.

Present theories on adult development and aging offer insights into how aging is characterized by gains and losses across different domains (e.g., social, emotional, physical, and cognitive).

Assessing alexithymia in chronic pain: psychometric properties of the Toronto Alexithymia Scale-20 and Perth Alexithymia Questionnaire.

Introduction: Alexithymia is elevated in chronic pain and relates to poor pain-related outcomes. However, despite concerns from other clinical populations, the psychometric properties of alexithymia measures have not been rigorously established in chronic pain.

Objective: This study examined the psychometric properties of the Toronto Alexithymia Scale-20 Item (TAS-20) and the Perth Alexithymia Questionnaire (PAQ) in adults with chronic pain.