A qualitative exploration of balancing family, work, and academics among female graduate nursing students in a lower-middle-income country.

Career women have varied responsibilities in society, and therefore, finding a balance among work, family, and personal life duties is becoming increasingly difficult. The literature explains that there is no one-size-fits-all standard for work-life balance. This study sought to explore ways of coping with family life and schooling among Ghanaian nurses and midwives pursuing graduate programmes without study leave.

Subjective Cognitive Decline in COPD - A Cross-Sectional Analysis of the Behavioral Risk Factor Surveillance System.

Background: Subjective cognitive decline (SCD), an early indicator of cognitive impairment, may affect COPD care and outcomes, yet its sociodemographic associations in Chronic Obstructive Pulmonary Disease (COPD) remain poorly understood.

Objective: To investigate the prevalence of SCD among people with COPD across different age groups and identify associations between demographics, risk behaviors, comorbidities, and self-reported SCD.

Design: Pooled 2019 BRFSS data from 24 states using the Cognitive Decline module were analyzed.

Bone marrow mesenchymal stem cells improve bone cancer pain by inhibiting p38MAPK phosphorylation and microglia activation.

Background: Bone cancer pain (BCP) is not adequately addressed by current treatment methods, making the exploration of effective management strategies a topic of significant interest. Bone marrow mesenchymal stem cells (BMSCs) seem to be a potential way for managing BCP, yet little is known about the mechanisms underlying the efficacy of this potential treatment.

Methods: We established the male C57BL/6 mice BCP models.

A Latent Class Analysis of Resilience and Its Relationship With Care Burden and Psychological Distress in Family Caregivers of Older Adults With Disability.

Given the challenging circumstances of aging with disability, family caregivers (FGs) face significant strain. Resilience, however, is a crucial protective factor against adverse caregiving outcomes. The study thus aimed to determine the latent classes of resilience among FGs and examine how these classes are related to care burden and psychological distress.

Validity and Reliability of the Korean Version of the Florida Patient Acceptance Survey.

Aim: To validate the Korean version of the Florida Patient Acceptance Survey (K-FPAS) and assess its reliability in evaluating the acceptance of implantable cardioverter defibrillators (ICDs) among Korean patients.

Design: A methodological research study was conducted to develop and validate the K-FPAS as a valuable tool for assessing ICD acceptance and its related factors in the Korean patient population.

Methods: A total of 243 participants, aged 18 years and older, who had received ICDs within the past year and were regularly monitored by cardiac specialists, were included in the study.

Critical care nurses' intention to leave and related factors: Survey results from 5 European countries.

Objectives: To determine the nursing intention to leave in critical care units and explore related factors along with work environment and sociodemographic variables.

Design And Setting: Quantitative cross-sectional study in five European countries (Spain, Poland, Croatia, Cyprus and Romania) through a self-administered survey in 2021.

Methods: The "AACN Critical elements of a healthy work environment scale.

Occurrence rate and risk factors for rest and procedural pain in critically ill patients: A systematic review and meta-analysis.

Objectives: To summarize the occurrence rates and identified the risk factors for pain at rest and during procedures in critically ill patients.

Methods: This study conducted a systematic review and meta-analysis. The Embase, PubMed, CINAHL Plus, Web of Science Core Collection and ProQuest Dissertations & Theses A&I databases were searched from inception to January 10, 2025, for relevant studies.

Nationwide Trends in Screen Time and Associated Risk Factors by Family Structures Among Adolescents, 2008-2022: Nationwide Cross-Sectional Study.

Background: Although understanding long-term trends in adolescent screen time and the influence of family structure is essential, there is a lack of research addressing these issues comprehensively.

Objective: This study aimed to conduct comprehensive investigations into adolescent screen time before and during the COVID-19 pandemic, with a particular focus on family structures.

Methods: This study used nationwide, large-scale data from the Korea Youth Risk Behavior Web-Based Survey from South Korea.

The prediction power of thymidine phosphorylase and IL-6 in the relapse of breast cancer.

Objective: Aim: To investigate the role of thymidine phosphate and IL-6 in the pathogenesis and survival rate in women with breast cancer..

Patients And Methods: Materials and Methods: Sixty women diagnosed with breast cancer (with age ranging between 25-65 years) were included in the current study.

The Association Between the Dietary Fatty Acid Fraction and Healthy Life Expectancy: Global Spatiotemporal Epidemiology from 2010 to 2019.

Background: As the global population ages, extending not only the life expectancy (LE) but also the healthy life expectancy (HALE) has become a critical public health objective. Dietary choices, especially the intake of various fatty acids, may play a role in achieving good health.

Objective: The aim of this study was to describe the intake of fatty acid (FA) fractions across different countries and explore its associations with HALE and LE from 2010 to 2019 according to publicly available international data.

Digitalizing the community health information system improved women's retention on the maternal continuum of care pathway in northwest Ethiopia: A quasi-experimental study.

Background: Retaining women on the maternal continuum of care pathway remains a significant challenge for the healthcare system. Digitalizing primary healthcare system using community health workers is a key strategy to enhance maternal healthcare utilization in Ethiopia. However, the effectiveness of digitalizing community health system using frontline health system workers is uncertain.

A systematic review of assessment tools for cognitive frailty: Use, psychometric properties, and clinical utility.

Background: The concept of 'cognitive frailty' (CF) was first developed by an international consensus group in 2013 and defined as evidence of both physical frailty and cognitive impairment without a clinical diagnosis of AD or another dementia. CF has been associated with adverse health outcomes and early identification is vital. Difficulty in the assessment of CF however is the lack of a diagnostic gold standard.

Strategies for relapse prevention among people with schizophrenia in KwaZulu-Natal Province, South Africa: Healthcare providers' perspectives.

Introduction: Relapse is a significant challenge among people with schizophrenia and is broadly recognized by the aggravation of positive or negative symptoms, the need for re-hospitalization, more intensive case management, and/or changes in medication. The quality of inpatient care and proper transition to outpatient care are crucial in reducing the risk of relapse. Healthcare providers play vital roles in ensuring the continuity of care after patients are discharged from the hospital.

Cancer nursing research priorities: findings from a cancer nurses' consultation in Europe.

Background: Nurses are well positioned to identify the most critical issues in patient care and to determine priorities for investigation. Involving nurses in developing research priorities may increase their engagement in research and enhance the development high-quality nursing practice.

Aim: This study aimed to scope the potential topics for future cancer nursing research in Europe from the perspective of cancer nurses.

Mechanistic Insights into SENP1 and OCT4 Interaction in Promoting Drug Resistance and Stem Cell Features in Colon Cancer.

This study explores the molecular mechanism by which sentrin/SUMO-specific protease 1 (SENP1) promotes cisplatin (Cis) resistance and tumor stem cell characteristics in colon adenocarcinoma (COAD) through desumoylation-mediated modification of octamer-binding transcription factor 4 (OCT4). By analyzing single-cell and transcriptome sequencing datasets, we identified key genes and regulatory pathways in both resistant and sensitive COAD cells. Malignant cells were isolated and evaluated for stemness using the infercnv package, and differential genes between Cis-resistant and -sensitive groups were identified.

Barriers and Facilitators to Cross-Institutional Referrals: System Configuration Analysis of VA Staff Experiences.

Background: In 2014 and 2018, respectively, Congress passed the Veterans Access, Choice, and Accountability Act (Choice Act) and the Maintaining Internal Systems and Strengthening Integrated Outside Networks Act (MISSION Act), which expanded eligibility for and use of cross-institutional referrals among U.S. Veterans enrolled in the Veterans Health Administration.

Frequency of Black and American Indian/Alaskan Native US Residents Screened for Firearm Access.

Objective: This study evaluates Black and AIAN individuals' self-reported history of being screened for firearm access by healthcare providers, and identifies factors that influence screening.

Methods: A cross-sectional, nationally representative survey of included 3015 Black and 527 AIAN adults in the US. Participants were recruited via probability-based sampling.

Predictors of the Intention to Stop Using Smart Devices at Bedtime Among University Students in Saudi Arabia: Cross-Sectional Survey.

Background: The widespread use of smart devices, particularly among university students, has raised concerns about their impact on sleep quality. Bedtime usage of smart devices is associated with sleep disruptions and poor sleep quality.

Objective: This study aimed to explore the behavioral and perceptual factors influencing university students' intention to stop using smart devices at bedtime in Saudi Arabia.

Awake Prone Positioning in Adults With COVID-19: An Individual Participant Data Meta-Analysis.

Importance: The impact of awake prone positioning (APP) on clinical outcomes in patients with COVID-19 and acute hypoxemic respiratory failure (AHRF) remains uncertain.

Objective: To assess the association of APP with improved clinical outcomes among patients with COVID-19 and AHRF, and to identify potential effect modifiers.

Data Sources: PubMed, Embase, the Cochrane Library, and ClinicalTrials.

Cue Detection and Self-Debriefing Techniques in Virtual Simulation: Techniques Using Cognitive Engineering Inspired Expertise Development Approaches.

Introduction: Online experiential learning can benefit learners with scalable techniques to self-debrief and to develop cognitive skills in recognizing clinical cues.

Methods: We developed techniques for cue-detection exercises and self-debriefing, based on cognitive engineering-inspired expertise development approaches that focus on tacit knowledge, sensemaking, and mental models. Self-debriefing was structured by asking the learners to compare and then reflect on their choices and rationales against those provided by a panel of experts.

The Association of Long COVID-19 Symptoms, Physical Function, and Activities of Daily Living Among Older Women.

Background: The impact of COVID-19 on physical function (PF) outcomes among older adults remains unclear. We examined the long-term association between COVID, PF, and Activities of Daily Living (ADLs) among women from the Women's Health Initiative (WHI).

Methods: Participants from the WHI who completed the COVID-19 survey (2021-2022) and annual survey (2022) were included.

A Model of the Determinants of Maternal Mortality for Indigenous Women.

Aims: To present a model of the determinants of maternal mortality for Indigenous women-social, structural, political and biological.

Design: Non-Indigenous academicians and an Indigenous tribal citizen and scholar partnered to amplify Indigenous women's voices.

Method: With epistemic decolonisation and Indigenist feminism as our theoretical basis, we used theory derivation to create a model of the determinants of Indigenous maternal mortality.

Associations Between Frailty, Family Functioning, and Quality of Life in Adolescents With Congenital Heart Disease: A Cross-Sectional Study.

Aim: To examine the relationship between frailty status, family functioning, and quality of life in adolescents with congenital heart disease (CHD).

Background: Frailty is a rarely assessed health outcome in adolescents. Despite advances in paediatric CHD treatment, potential complications may cause frailty, affecting family dynamics and quality of life.