3 results match your criteria: "College of Life Science and Technology Guangxi University Nanning China.[Affiliation]"
The phytopathogen senses and effluxes salicylic acid via a sensor HepR and an RND family efflux pump to promote virulence in host plants.
mLife
September 2024
State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic and Developmental Sciences, School of Life Sciences and Biotechnology Shanghai Jiao Tong University Shanghai China.
Article Synopsis
- Salicylic acid (SA) is crucial for plant defense against certain pathogens, and its levels spike significantly at infection sites, yet how pathogens cope with this SA stress is still unclear.
- Research identified a specific operon (Xcc4167-Xcc4171) in the pathogen Xcc that encodes a transcription factor (HepR) and an SA efflux pump (HepABCD), both of which play roles in sensing and evicting SA during infection.
- The study concluded that HepR acts as a novel SA sensor that regulates the operon's expression, and the efflux pump is essential for Xcc's virulence in host plants like Chinese radish and cabbage.
Insertion sequence transposition activates antimycobacteriophage immunity through an -silenced lipid metabolism gene island.
mLife
March 2024
State Key Laboratory for Conservation and Utilization of Subtropical Agro-Bioresources, Guangxi Research Center for Microbial and Enzyme Engineering Technology, College of Life Science and Technology Guangxi University Nanning China.
Insertion sequences (ISs) exist widely in bacterial genomes, but their roles in the evolution of bacterial antiphage defense remain to be clarified. Here, we report that, under the pressure of phage infection, the IS transposition of into the gene can occur at high frequencies, which endows the mutant mycobacterium with a broad-spectrum antiphage ability. Lsr2 functions as a negative regulator and directly silences expression of a gene island composed of 11 lipid metabolism-related genes.
View Article and Find Full Text PDFHuangjiu (Chinese rice wine) is a popular and traditional alcoholic beverage in China; however, the consumption of Huangjiu readily results in hangover symptoms. The aim of this study was to identify the main components associated with behavioral inhibition, headache, and the relevant mechanisms by using a mice hangover model. The results of an open-field experiment revealed that the key biogenic amine associated with mice behavior was histamine, which inhibited the behavior activity of mice in a dose-dependent manner.
View Article and Find Full Text PDF