[Treatment program for dual-diagnosis substance abusers].

Dual-diagnosis mentally ill patients, i.e. those characterized with substance abuse problems combined with mental health problems, are a challenge both for systems treating substance abusers and for mental health services.

Resonance Cassie-Wenzel wetting transition for horizontally vibrated drops deposited on a rough surface.

The transition between the Cassie and Wenzel wetting regimes has been observed under horizontal vibrations of a water drop placed on the rough micrometrically scaled polymer pattern. The observed transition has a distinct resonance character. The resonance frequencies as established experimentally coincide with the calculated eigenfrequencies of capillary-gravity standing waves on the drop surface.

Prefrontal and parietal regions are involved in naming of objects seen from unusual viewpoints.

Object naming is commonly used for demonstrating semantic memory abilities, known to be affected in normal aging. Yet, neuropsychological assessments of older people do not reflect irregularities. The authors used a test with 2 levels of naming complexity by 2 kinds of stimuli: common objects pictured from a conventional viewpoint (usual condition) or from an unconventional viewpoint (unusual condition).

Purification and identification of a novel leucine aminopeptidase from Bacillus thuringiensis israelensis.

A novel leucine aminopeptidase was purified from a Bacillus thuringiensis israelensis (Bti) culture. The purification stages included heating the concentrated supernatant to 65 degrees C for 90 min, anion-exchange chromatography by DEAE cellulose, and hydrophobic chromatography by phenyl Sepharose. The specific activity of leucine aminopeptidase after the hydrophobic chromatography increased by 215.

Geometry of Hamiltonian chaos.

The characterization of chaotic Hamiltonian systems in terms of the curvature associated with a Riemannian metric tensor in the structure of the Hamiltonian is extended to a wide class of potential models of standard form through definition of a conformal metric. The geodesic equations reproduce the Hamilton equations of the original potential model when a transition is made to an associated manifold. We find, in this way, a direct geometrical description of the time development of a Hamiltonian potential model.

Specific targeting to murine myeloma cells of Cyt1Aa toxin from Bacillus thuringiensis subspecies israelensis.

Multiple myeloma is currently an incurable cancer of plasma B cells often characterized by overproduction of abnormally high quantities of a patient-specific, clonotypic immunoglobulin "M-protein." The M-protein is expressed on the cell membrane and secreted into the blood. We previously showed that ligand-toxin conjugates (LTC) incorporating the ribosome-inactivating Ricin-A toxin were very effective in specific cytolysis of the anti-ligand antibody-bearing target cells used as models for multiple myeloma.

Cassie-Wenzel wetting transition in vibrating drops deposited on rough surfaces: is the dynamic Cassie-Wenzel wetting transition a 2D or 1D affair?

The transition between the Cassie and Wenzel wetting regimes has been observed under vertical vibration of a water drop placed on a rough micrometrically scaled polymer pattern. The transition takes place under the constant force per unit length of the triple contact line, not under constant pressure. A study of the vibrating drop deposited on the rough surface supplied valuable information concerning the Cassie-Wenzel wetting transition.

Environmental scanning electron microscopy study of the fine structure of the triple line and cassie-wenzel wetting transition for sessile drops deposited on rough polymer substrates.

The wetting of rough honeycomb micrometrically scaled polymer substrates was studied. A very strong dependence of the apparent contact angle on the drop volume has been established experimentally. The environmental scanning electron microscopy study of the fine structure of the triple line is reported first.

Why do pigeon feathers repel water? Hydrophobicity of pennae, Cassie-Baxter wetting hypothesis and Cassie-Wenzel capillarity-induced wetting transition.

Wetting of pigeon feathers has been studied. It was demonstrated that the Cassie-Baxter wetting regime is inherent for pigeon pennae. The water drop, supported by network formed by barbs and barbules, sits partially on air pockets.

Criminal mediation for minors in Israel.

Mediation was introduced in Canada in 1974 in order to handle a crime of robbery and vandalization committed by adolescents. After mediation, these adolescents agreed to apologize to each of their victims and pay restitution. Several countries (Canada, England, Finland, and the U.

Antidepressant-induced undesirable weight gain: prevention with rimonabant without interference with behavioral effectiveness.

Antidepressant pharmacotherapy has dramatically improved the quality of life for many patients. However, prolonged use may induce weight gain, resulting in enhanced risk for treatment noncompliance. Cannabinoid CB(1) receptor antagonists decrease food intake and body weight, but may also affect mood.

Wetting properties of the multiscaled nanostructured polymer and metallic superhydrophobic surfaces.

A superhydrophobic surface is produced from industrial grade polymer materials. The surface comprises partly disordered triple-scaled arrays of polyvinylidene fluoride (PVDF) globules. An inherently superhydrophobic metallic surface is produced with polymer template.

Droplet behavior on flat and textured surfaces: co-occurrence of Deegan outward flow with Marangoni solute instability.

It is demonstrated experimentally that the solution droplet behavior is governed by the co-occurrence of outward hydrodynamic and surface tension (solute Marangoni) induced flows. Potassium ferrocyanide allows the effective visualization of the processes taking place in the droplet. Wetting properties of the substrate govern the shape evolution of the evaporated droplet.

Quasi-phase-matched generation of optical intensity waves.

The evolution of modulated light in a nonlinear medium, when described in terms of intensity waves, depends critically on a phase-matching condition for the intensity waves. We formally develop the conditions for quasi-phase matching of the interacting intensity waves and show that a periodic nonlinearity can be utilized to eliminate the dephasing between them. This is verified using stimulated Brillouin scattering with a periodically nonlinear optical fiber that has a period length equal to one-half of the (modulation) wavelength of the intensity waves.

Cyt1Ca from Bacillus thuringiensis subsp. israelensis: production in Escherichia coli and comparison of its biological activities with those of other Cyt-like proteins.

The larvicidal activity of Bacillus thuringiensis subsp. israelensis against dipteran larvae is determined by four major polypeptides of the parasporal crystalline body produced during sporulation. Cyt1Aa shows the lowest toxicity when used alone but is the most synergistic with any of the other proteins.

Objective and subjective stressors and the psychological adjustment of melanoma survivors.

This study of 300 melanoma survivors examines the relative contributions of objective illness-related factors (stage of illness at diagnosis, time since diagnosis, and change in physical condition) and of subjective factors (cognitive appraisal) to their psychological adjustment. The findings show that lower appraisal of their situation as a threat, higher appraisal of it as a challenge, and higher appraisal of their subjective ability to cope with it all increased their well-being, while lower threat appraisal and higher appraisal of subjective ability to cope also reduced their distress. These findings, which are consistent with Lazarus and Folkman's stress coping theory, suggest that subjective factors may be more important than objective medical factors in predicting patients' adjustment.

Micrometrically scaled textured metallic hydrophobic interfaces validate the Cassie-Baxter wetting hypothesis.

The possibility of forming a hydrophobic metallic interface is shown when it is micrometrically textured. On such surface obtained by gold coating the polymer honeycomb template, the apparent contact angle of water was observed to be close to or greater than 90 degrees . The metal hydrophobicity is explained by trapping air inside pores of pattern according to the Cassie-Baxter wetting model.

Intracellular chemiluminescence activates targeted photodynamic destruction of leukaemic cells.

Photodynamic therapy (PDT) involves a two-stage process. A light-absorbing photosensitiser (Ps) is endocytosed and then stimulated by light, inducing transfer of energy to a cytoplasmic acceptor molecule and the generation of reactive oxygen species that initiate damage to cellular membrane components and cytolysis. The expanded use of PDT in the clinic is hindered by the lack of Ps target-cell specificity and the limited tissue penetration by external light radiation.

Development of a capitation scale for IDF career soldiers in Israel.

The Israeli National Health Insurance Law allocates a national healthcare budget to the sickness funds, which provide medical care to civilian population. Medical care for members of the IDF is financed through the budget of the Ministry of Defense and is not included in the national healthcare budget. Benefits provided to soldiers serving in the permanent forces are far more extensive than those provided to civilians.

Finger pulse waveform length in the detection of concealed information.

An attempt was made to assess the efficiency of the finger pulse waveform length (FPWL), in detection of concealed information. For this purpose, two mock-theft experiments were designed. In the first, 40 guilty participants were examined while electrodermal, respiration and finger pulse volume were recorded.

Antioxidant protective mechanisms against reactive oxygen species (ROS) generated by mitochondrial P450 systems in steroidogenic cells.

Mitochondrial P450 type enzymes catalyze central steps in steroid biosynthesis, including cholesterol conversion to pregnenolone, 11beta and 18 hydroxylation in glucocorticoid and mineralocorticoid synthesis, C-27 hydroxylation of bile acids, and 1alpha and 24 hydroxylation of 25-OH-vitamin D. These monooxygenase reactions depend on electron transfer from NADPH via FAD adrenodoxin reductase and 2Fe-2S adrenodoxin. These systems can function as a futile NADPH oxidase, oxidizing NADPH in absence of substrate, and leak electrons via adrenodoxin and P450 to O(2), producing superoxide and other reactive oxygen species (ROS).

Students of physical therapy. A comparative study of student profiles at a college and university in Israel.

This study focuses on the attributes of students of physical therapy in order to compare the profiles of students of physical therapy (PT) in two institutions of higher learning in Israel: Ben Gurion University (BGU) and the Academic College of Judea and Samaria (ACJS). This study focuses on a department where studies have an occupational/ applicative/practical orientation and high status in the higher education system. Findings of this study indicate broad similarities in the profiles of students at both institutions in relation to their age, family status, country of origin, number of siblings, parental education, and financial status of student family of origin.

Low back pain incident episodes: a community-based study.

Background Context: The available evidence regarding low back pain (LBP) incident episodes is not consistent. Such knowledge can add information for the potential contribution of preventive programs.

Purpose: a) To evaluate annual incident episodes of LBP among the general population.

Cyt2Ba of Bacillus thuringiensis israelensis: activation by putative endogenous protease.

The gene cyt2Ba of Bacillus thuringiensis subsp. israelensis was cloned for expression, together with p20, in an acrystalliferous strain. The large hexagonal crystals formed were composed of Cyt2Ba, which facilitated its purification.

Patterning in rapidly evaporated polymer solutions: formation of annular structures under evaporation of the poor solvent.

Patterning in the intensively evaporated polymer solutions based on polystyrene and poor solvent (acetone) was investigated. SEM and AFM studies demonstrated that annular elements of the surface topography are formed in this case, in contrast to the honeycomb patterns obtained under the evaporation of the good solvent (chloroform). The authors suggest that the theory of viscous dewetting developed by de Gennes explains the phenomenon satisfactorily.