Individuals' Desire for Social Needs Sharing Among Healthcare Providers: Findings from the 2022 Health Information National Trends Survey.

Background: Increasingly, health systems are collecting and using social needs data, yet there is limited information about individuals' preferences for how social needs information is shared among providers for treatment purposes.

Objective: To explore the connection between experiencing social needs and concerns about healthcare providers sharing social needs information.

Design And Participants: A nationally representative, cross-sectional study of 6252 US community-dwelling adults (≥ 18 years of age) who responded to the Health Information National Trends Survey (HINTS 6) (response rate 28.

Screening of Oxidative Stress-related Biomarkers and Antioxidant Drugs for Polycystic Ovary Syndrome Based on Bioinformatics and Molecular Docking.

Polycystic ovary syndrome (PCOS) is a prevalent endocrine and metabolic disorder affecting women of reproductive age. Oxidative stress (OS) is suggested to play a significant role in the development of PCOS. Using antioxidants to reduce OS and maintain a healthy balance in the body could be a novel treatment approach for PCOS.

Synergistic effect of Canarium strictum leaves extract and KI on the corrosion protection of mild steel in 15% HCl solution.

The inhibitory potential of an alcoholic extract derived from Canarium strictum leaves (CSL) was evaluated as a corrosion inhibitor for mild steel (MS) in 15% HCl solution. Furthermore, to enhance its inhibition effectiveness, the influence of potassium iodide (KI) was also examined. The corrosion inhibition and adsorption characteristics of CSL were comprehensively analysed through weight loss measurement, electrochemical impedance measurement (EIS), potentiodynamic polarization (PP), UV-visible spectroscopy, Fourier transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), scanning electron microscopy and energy dispersive spectroscopy (SEM-EDS).

Development of a handheld GPU-assisted DSC-TransNet model for the real-time classification of plant leaf disease using deep learning approach.

In agriculture, promptly and accurately identifying leaf diseases is crucial for sustainable crop production. To address this requirement, this research introduces a hybrid deep learning model that combines the visual geometric group version 19 (VGG19) architecture features with the transformer encoder blocks. This fusion enables the accurate and précised real-time classification of leaf diseases affecting grape, bell pepper, and tomato plants.

Healthy Lifestyle in the First 1000 Days and Overweight and Obesity Throughout Childhood.

Objectives: Investigate associations of different family healthy lifestyle scores (HLS) during the first 1000 days with childhood overweight and obesity (OWOB).

Methods: Cohort-specific analyses were conducted on participants (n = 25 006) from 4 European birth cohorts (The study on the pre- and early postnatal determinants of child health and development [EDEN], Elfe, France; Generation R, the Netherlands; and Lifeways, Ireland). Three composite HLSs were calculated: a maternal pregnancy HLS based on prepregnancy body mass index (BMI) and diet quality, physical activity, smoking status, and alcohol consumption during pregnancy; a parental pregnancy HLS additionally considering paternal BMI and smoking status; and an infancy HLS based on breastfeeding duration, age of solid food introduction, and exposure to passive smoking.

Alternative splicing of vascular calcification: Insights, opportunities, and challenges.

Vascular calcification(VC) significantly increases the risk of cardiovascular events, leading to thickening of the myocardium and arteries, coronary heart disease, heart failure, and potentially triggering myocardial infarction and sudden cardiac death. Although VC is a reversible process, there are currently no methods or medications in clinical practice that can completely reverse or cure it. The current treatment strategies primarily focus on slowing the progression of VC and exploring new diagnostic and therapeutic approaches, making the identification of early diagnostic markers for VC particularly important.

Sodium alginate/low methoxyl pectin composite hydrogel beads prepared via gas-shearing technology for enhancing the colon-targeted delivery of probiotics and modulating gut microbiota.

The probiotic encapsulation system has the potential to enhance the prebiotic effects of probiotics. However, challenges arise from the release behavior of this system in vivo and the large size of hydrogel beads. This study aims to address the issues related to the size of previous hydrogel beads and assess the colon-targeted delivery of probiotic polysaccharides composite hydrogel beads (PPHB).

Carbon quantum dots amplify beneficial effects of EGCG against neural injuries by NLRP3 inflammasome after intracerebral hemorrhage.

Neuroinflammation plays an indispensable role in neural damages after ICH, responsible for the induced high mortality and poor prognosis. NLRP3 inflammasome, which is known mediated by ROS, has been widely documented to aggravate brain injuries. Therefore, suppressing neural injuries by ROS/NLRP3 pathway may be beneficial in treating ICH.

Computational identification and experimental validation of novel microRNAs along with their targets through RT-PCR approach.

Various metabolic and cell signaling processes impact the functions of sugarcane plant cells. MicroRNAs (miRNAs) play critical regulatory roles in enhancing yield and providing protection against various stressors. This study seeks to identify and partially characterize several novel miRNAs in sugarcane using tools, while also offering a preliminary assessment of their functions.

Cracking the code of acrylamide and Nε-(carboxymethyl)lysine: Fish oil use and predictive strategies in potato chips during thermal processing.

Global high consumption of fried potatoes is driven by appealing taste and edible convenience. However, the occurrence of Maillard reaction hazardous products (MRHPs) and joint control recipes have scarcely been concerned. We aim to reveal and predict how fish oil treatment for potato slices reduces simultaneous formation of typical MRHPs in air-based thermal processed potato chips.

Changes of digestive stability and potential allergenicity of high hydrostatic pressure-treated ovalbumin during in vitro digestion.

Food allergens are defined by their stability during digestion, with allergenicity largely influenced by resistance to enzymatic hydrolysis. Ovalbumin (OVA), a major egg protein, is a significant contributor to food allergies, particularly in children. Our previous work demonstrated that high hydrostatic pressure (HHP) treatment reduces OVA allergenicity by disrupting conformational epitopes and altering its structure.

Molecular dynamics simulation revealing the interactions between toxic aldehydes and starch: A case study of malondialdehyde, 4-hydroxy-2-hexenal, and 4-hydroxy-2-nonenal in starch-based food during frying.

Toxic compounds in fried food products attract increasing attention, but studies regarding the levels of common toxins, such as malondialdehyde (MDA), 4-hydroxy-2-hexenal (4-HHE), and 4-hydroxy-2-nonenal (4-HNE), in fried starch-based food (FSBF) are scarce. Herein, we investigated the formation and distributions of these aldehydes in FSBF, and the frying oil and FSBF retained higher levels of low-molecular-weight aldehydes. The highest aldehyde concentrations were observed in French fries.

Pathways of 2-amino-1-methyl-6-phenylimidazo [4,5-b] pyridine (PhIP) inhibited by basic amino acids in the glucose/ creatinine/ phenylalanine model system.

This study aimed to investigate the inhibitory pathways of basic amino acids (Histidine, Lysine, and Arginine) on the formation of PhIP in the glucose/creatinine/phenylalanine model system. The inhibitory effects were found to depend on both the chemical structure and concentration of the basic amino acids, with Lysine showing the strongest inhibitory effect. Due to the lower reaction barrier of basic amino acids, their potential inhibitory mechanism is proposed to involve competition with phenylalanine for glucose.

Proteinaceous corals reveal heterogeneity in shifting Southern California oceanographic regimes.

The Southern California Bight is an ecologically important region for many local and migratory fauna. We combine bulk and compound-specific amino acid stable isotope measurements in the skeletons of proteinaceous octocorals with new regional ocean modeling system model output to explore biogeochemical changes at two locations within the Bight - Santa Cruz Basin and Santa Barbara Channel. Separated by the Channel Islands, these sites display distinct oceanographic regimes.

Tracing microplastics in environmental sources and migratory shorebirds along the Central Asian Flyway.

Microplastic pollution poses a significant threat to coastal ecosystems worldwide. Despite its widespread occurrence, knowledge on the prevalence and fate of microplastics across food webs is limited. To bridge this gap, we conducted an extensive study on microplastic contamination in mudflats, mangroves, and sand beaches being key habitats for wintering shorebirds on the west coast of India.

Antibiotic resistance gene pollution in poultry farming environments and approaches for mitigation: A system review.

Antibiotic resistance genes (ARG) pollution in poultry farming environments has become increasingly critical, primarily driven by the widespread use of antibiotics in animal husbandry. Prolonged antibiotic use has led to the emergence of ARGs and antibiotic-resistant bacteria, spreading via horizontal and vertical gene transfer. The complexity of ARG pollution in poultry farming arises from the unique farming practices, physiological characteristics of poultry, and manure management methods, with manure, wastewater, and air serving as significant vectors for ARG dissemination.

Probiotics improve eggshell quality via regulating microbial composition in the uterine and cecum.

Probiotics benefit the health and production performance of chickens, but their impact on egg and eggshell quality, particularly in the later stage, remains unclear. Here, 1-day-old Tianfu green shell-laying hens were fed either non-probiotics feed (n = 180) or feed supplemented with 100 mg / kg probiotics (n = 180). 16S rDNA sequencing indicated that dietary probiotics decreased the distribution of uterine p_Firmicutes, g_Fusobacterium, and s_Fusobacterium_unclassified, while increased p_Proteobacteria, g_Ralstonia, and s_Ralstonia_unclassified.

Health risk assessment of dietary cadmium exposure based on cadmium bioavailability in food: Opportunities and challenges.

Long-term exposure to Cd through contaminated food can lead to multiple adverse health effects on humans. Although previous studies have covered global food Cd concentrations and dietary Cd exposures across different populations, there are increasing concerns regarding the adequacy of current food Cd safety standards to protect populations from adverse health effects. Moreover, incorporation of Cd relative bioavailability (Cd-RBA) in foods improves the accuracy of health risk assessment.

Ionic liquid-modified magnetic covalent organic framework for the extraction of four pyrethroids in traditional Chinese herbs.

Efficient enrichment of analytes and purification of matrices are crucial for the highly sensitive detection and monitoring of pesticides in traditional Chinese herbs. This work prepared magnetic ionic liquid-controlled covalent organic framework (IL-COF@FeO) as the sorbent via a simple in-situ precipitation polymerization and thiolene "click" strategy. The IL-COF@FeO exhibited remarkable adsorption performance towards pyrethroids within 5 min.

Construction and characterisation of mung bean protein isolate/carboxymethyl konjac glucomannan sodium hydrogels: Gel properties, structural properties, microstructure, sodium salt release, and 3D printing.

This study proposed a hydrogel system using mung bean protein isolate (MPI) and carboxymethyl konjac glucomannan (CKGM). The effects of CKGM addition on the gel properties, structural characteristics, and Na loading capacity of the MPI-CKGM system were investigated. FTIR and molecular docking techniques demonstrated that MPI and CKGM formed hydrogels via hydrogen bonding interactions.

Advances in High-Resolution Mass Spectrometry-Based Metabolomics: Applications in Food Analysis and Biomarker Discovery.

Consumer concerns regarding food nutrition and quality are becoming increasingly prevalent. High-resolution mass spectrometry (HRMS)-based metabolomics stands as a cutting-edge and widely embraced technique in the realm of food component analysis and detection. It boasts the capability to identify character metabolites at exceedingly low abundances, which remain undetectable by conventional platforms.

Development, validation, and reliability testing of the College Perspectives around Food Insecurity survey.

The objective of this study was to develop and to test the validity and reliability of a survey aimed to evaluate internal and external factors associated with college food insecurity. Researchers used a mixed methods approach to evaluate the College Perspectives around Food Insecurity survey. Survey items were constructed from interview data and assigned a social cognitive theory concept (environment, personal, or behavior).

Aspartate Metabolism-Driven Gut Microbiota Dynamics and RIP-Dependent Mitochondrial Function Counteract Oxidative Stress.

Aspartate (Asp) metabolism-mediated antioxidant functions have important implications for neonatal growth and intestinal health; however, the antioxidant mechanisms through which Asp regulates the gut microbiota and influences RIP activation remain elusive. This study reports that chronic oxidative stress disrupts gut microbiota and metabolite balance and that such imbalance is intricately tied to the perturbation of Asp metabolism. Under normal conditions, in vivo and in vitro studies reveal that exogenous Asp improves intestinal health by regulating epithelial cell proliferation, nutrient uptake, and apoptosis.

Transcriptome Reveals the Promoting Effect of Beta-Sitosterol on the Differentiation of Bovine Preadipocytes.

Natural small molecule compounds play crucial roles in regulating fat deposition. Beta-sitosterol exhibits multiple biological activities such as cholesterol reduction and anticancer effects. However, its regulatory mechanism in the differentiation of bovine preadipocytes remains unclear.