Calcium deficiency and its implications for cardiovascular disease and cancer: Strategies for resolution via agronomic fortification.

Calcium (Ca) is a vital nutrient essential for structural development and signal transmission in both plants and animals. In humans, inadequate calcium intake has been correlated with various diseases, including osteoporosis, cardiovascular and cerebrovascular diseases, and cancer. In areas where plants serve as a main dietary source, calcium intake is significantly lower than the recommended adequate intake, notably in low- and middle-income countries (LMICs).