2 results match your criteria: "College of Biotechnology and Bioengineering Sungkyunkwan University (SKKU) Suwon Republic of Korea.[Affiliation]"
Bioprinted hASC-laden collagen/HA constructs with meringue-like macro/micropores.
Bioeng Transl Med
September 2022
Department of Biomechatronic Engineering, College of Biotechnology and Bioengineering Sungkyunkwan University (SKKU) Suwon Republic of Korea.
Extrusion-based bioprinting is one of the most effective methods for fabricating cell-laden mesh structures. However, insufficient cellular activities within the printed cylindrical cell-matrix blocks, inducing low cell-to-cell interactions due to the disturbance of the matrix hydrogel, remain to be addressed. Hence, various sacrificial materials or void-forming methods have been used; however, most of them cannot solve the problem completely or require complicated fabricating procedures.
View Article and Find Full Text PDFFabrication of bone-derived decellularized extracellular matrix/ceramic-based biocomposites and their osteo/odontogenic differentiation ability for dentin regeneration.
Bioeng Transl Med
September 2022
Department of Biomechatronic Engineering, College of Biotechnology and Bioengineering Sungkyunkwan University (SKKU) Suwon Republic of Korea.
Article Synopsis
- The study aimed to create bioactive biocomposites using decellularized extracellular matrix (dECM) and calcium phosphate, assessing their impact on the differentiation of human dental pulp stem cells (hDPSCs).
- High-quality cell-laden 3D biocomposites were successfully produced, with over 90% cell viability and stable printing properties, leading to positive evaluations of cytotoxicity and cell differentiation.
- Results indicated that dECM-based biocomposites significantly enhance osteogenic activity and promote odontogenic differentiation in hDPSCs, with successful tissue formation observed after implantation in mice, suggesting potential for use in dental tissue engineering.