Ocotillol-Type Pseudoginsenoside-F11 Alleviates Lipopolysaccharide-Induced Acute Kidney Injury through Regulation of Macrophage Function by Suppressing the NF-κB/NLRP3/IL-1β Signaling Pathway.

Acute kidney injury (AKI) is characterized by a sudden decline in renal function. The inflammatory response is the fundamental pathologic alteration throughout AKI, regardless of the various causal factors. Macrophages are the main immune cells involved in the inflammatory microenvironment in AKI.

Pyxinol Fatty Acid Ester Derivatives J16 against AKI by Selectively Promoting M1 Transition to M2c Macrophages.

Acute kidney injury (AKI) is a common, multicause clinical condition that, if ignored, often progresses to chronic kidney disease (CKD) and end-stage kidney disease, with a mortality rate of 40-50%. However, there is a lack of universal treatment for AKI. Inflammation is the basic pathological change of early kidney injury, and inflammation can exacerbate AKI.

Morphologic analysis of Chinese lumbar endplate by three-dimensional computed tomography reconstructions for helping design lumbar disc prosthesis.

Lumbar disc prostheses have been used increasingly in recent years. The successful design of lumbar disc prostheses depends on accurate morphometric parameters. However, the morphologic dimensions of lumbar endplate area have not been investigated in Chinese population.

Primary cardiac sarcoma complicated with cerebral infarction and brain metastasis: A case report and literature review.

In large autopsy series, the estimated frequency of primary tumors of the heart ranges from 0.0017% to 0.33%.

An anatomic study of trifurcate iliotibial bands for correcting valgus knee deformity.

Background: The iliotibial band (ITB) trifurcates into the anterior, central and posterior branches at the knee level, and sometimes the branches must be selectively released to correct the valgus knee deformity during total knee arthroplasty. However, the anatomical morphology of the trifurcate ITBs has not been investigated.

Methods: Fifty-two knees from 26 embalmed cadavers were dissected to observe and record the relationship of the three branches given off from the ITB trifurcation.

Sulforaphane protection against the development of doxorubicin-induced chronic heart failure is associated with Nrf2 Upregulation.

Background: Doxorubicin (DOX) is an anthracycline antitumor drug. However, its clinical use is limited by dose-dependent cardiotoxicity and even progresses to chronic heart failure (CHF).

Objective: This study aims to investigate whether the Nrf2 activator, sulforaphane (SFN), can prevent DOX-induced CHF.

Morphologic evaluation of Chinese cervical endplate and uncinate process by three-dimensional computed tomography reconstructions for helping design cervical disc prosthesis.

Background: Cervical disc prostheses have been used increasingly in recent years. The successful design of cervical disc prostheses depends on accurate morphometric parameters. However, the morphologic dimensions of the cervical endplate area have not been investigated in the Chinese population.

Bryan Cervical Disc Arthroplasty Versus Anterior Cervical Discectomy and Fusion for Treatment of Cervical Disc Diseases: A Meta-analysis of Prospective, Randomized Controlled Trials.

Study Design: A meta-analysis of randomized controlled trials (RCTs).

Objective: The purpose of this study is to evaluate the effectiveness and safety of Bryan cervical disc arthroplasty (BCDA) as compared with anterior cervical discectomy and fusion (ACDF) for treatment of cervical disc diseases (CDDs).

Summary Of Background Data: Previous meta-analyses focused on the comparison of effectiveness and safety between ACDF and CDA, which consisted of various types of disc prostheses.