Functional impairment in COPD can be predicted using genomic-derived data.

Objective: Reduced functional capacity and muscle weakness are two major contributors to functional impairment in chronic obstructive pulmonary disease (COPD). The underlying causes of functional impairment are poorly understood and, therefore, we sought to investigate the contribution of genetic factors.

Methods: We conducted a cross-sectional analysis of sociodemographic, clinical and genetic information of people with COPD.

Behind the scenes of palliative care: Qualitative study with oncology family caregivers.

Purpose: Long-term caregiving tasks can be exhausting for family caregivers, resulting in high psychological morbidity. The study aims to explore the experiences, challenges, and strengths of family caregivers providing care for cancer patients in palliative care, in-patient or at home.

Method: Nine caregivers were included, predominantly women aged 34 to 70, from various regions of Portugal.

Improving Motor Competence of Children: The "Super Quinas" Intervention Program in Portuguese Primary Schools.

Objectives: The objective of this study was to describe the effects of an extra hour of a structured motor program on the motor competence (MC) of children 6-10 years old..

Design: The need for movement interventions to enhance MC among school-aged children has gained vital importance in the last years, given the negative secular trends reported.

Immunotherapy in gastric cancer-A systematic review.

Background: Gastric Cancer (GC) is the 5th most prevalent and 4th most deadly neoplasm globally. Immunotherapy has emerged as a promising treatment approach in GC, potentially improving positive clinical outcomes while addressing the limitations of conventional therapies. GC immunotherapy modalities consist of adoptive cell therapy (ACT), cancer vaccines, and immune checkpoint inhibitors (ICI).

Dietary Surveys and Nutritional Epidemiology.

As the prevalence of lifestyle-related diseases continues to increase globally [...

Prescribed Hospital Diet Influence on Dietary Intake of Hospitalised Patients: A Cross-Sectional Study.

Background: The dietary intake of hospitalised patients is often compromised during hospitalisation, which can be a causal factor for hospital malnutrition. This is considered a public health problem worldwide and is associated with an increased risk of other complications.

Objectives: Our objective was to determine the dietary intake of hospitalised individuals and if the prescribed diet influences it.

Processed Food Consumption and Sleep Quality in School-Aged Children: Insights from a Cross-Sectional Study.

Objective: This cross-sectional study aimed to investigate the association between processed food consumption and sleep quality among school-aged children.

Methods: Our sample consisted of 137 children, with 52.6% being girls with a mean age of 7.

Early-Stage Luminal B-like Breast Cancer Exhibits a More Immunosuppressive Tumor Microenvironment than Luminal A-like Breast Cancer.

Background: Breast cancer is a heterogeneous malignant disease with a varying prognosis and is classified into four molecular subtypes. It remains one of the most prevalent cancers globally, with the tumor microenvironment playing a critical role in disease progression and patient outcomes.

Methods: This study evaluated tumor samples from 40 female patients with luminal A and B breast cancer, utilizing flow cytometry to phenotypically characterize the immune cells and tumor cells present within the tumor tissue.

Impact of Physical Exercise on Breast Cancer-Related Lymphedema and Non-Invasive Measurement Tools: A Systematic Review.

Breast cancer-related lymphedema (BCRL) is a chronic disease with lasting effects, making it one of the most feared sequelae of breast cancer with significant personal and social impacts. Therapeutic exercises play a fundamental role in its treatment. This systematic review aims to provide the most up-to-date findings on the impact of physical exercise on the management of BCRL.

Effectiveness of Global Postural Reeducation in Postural Changes and Postural Stability in Young Adults.

Background: Postural changes are considered a public health issue and have gathered significant interest in both research and clinical practice.

Aims: To evaluate the effectiveness of Global Postural Reeducation (GPR) in improving postural changes and postural stability in healthy young adults. Additionally, this study aims to identify the main postural changes in the sample population.

The Mental Health of Older People Living in Nursing Homes in Northern Portugal: A Cross-Sectional Study Protocol.

: In Portugal, evidence regarding the mental health of institutionalized older people is limited, leaving this area poorly described and the mental health needs of this population largely unknown. This research aims to describe the mental health of older persons residing in nursing homes in Northern Portugal. : A cross-sectional study will be conducted.

Intervention Programmes for First-Episode Psychosis: A Scoping Review.

The aim of this scoping review was to map intervention programmes for first-episode psychosis by identifying their characteristics, participants, and specific contexts of implementation. It seems reasonable to suggest that early intervention may be beneficial in improving recovery outcomes and reducing the duration of untreated psychosis (DUP). Despite the expansion of these programmes, there are still some significant variations and barriers to access that need to be addressed.

Optimizing Muscle Performance in Young Soccer Players: Exploring the Impact of Resisted Sprint Training and Its Relationship with Distance Covered.

Background: Speed training with resisted sprints has been shown to positively affect neuromuscular performance in soccer players. Various loads, ranging from 10% to 120% of body mass, have demonstrated performance improvements across the spectrum. However, the impact of sprint distance with optimal load on these adaptive responses has yet to be thoroughly described.

Decoding Urinary Tract Infection Trends: A 5-Year Snapshot from Central Portugal.

Introduction: This study analyzes urinary tract infections (UTIs) in a hospital in Central Portugal over a five-year period, focusing on bacterial prevalence, patient demographics, and antibiotic resistance patterns. This investigation aims to provide insights that can guide improved infection control and treatment strategies.

Methods: A total of 6161 positive urine cultures collected over five years were examined, with particular emphasis on 2019 due to a peak in infection rates.

Playing a serious game to increase fertility awareness: perceptions of adolescents, parents and teachers.

Infertility is increasing globally, affecting one in six adults due to factors like delayed childbearing and lifestyle changes. Despite the recognition of the importance of increasing fertility awareness, levels remain low. This study evaluated the perceptions of 'FActs!', a serious game aimed at improving adolescents' fertility awareness.

Validation of the Portuguese version of the Movement Disorder Society non-motor rating scale (MDS-NMS) in Parkinson's disease.

Background: The Movement Disorder Society Non-Motor Rating Scale (MDS-NMS) serves as a comprehensive clinical assessment tool for non-motor symptoms in Parkinson's disease (PD) OBJECTIVES: This study aims to validate the Portuguese version of the MDS-NMS, addressing the critical need for culturally adapted rating scales in Portuguese-speaking populations.

Methods: This multicenter, cross-sectional study engaged native Portuguese-speaking PD patients from 16 Movement Disorders Centers across Portugal and Brazil. We conducted a meticulous translation process into Portuguese, including forward-backward translation and cognitive pretesting.

Allergic Rhinitis and its Impact on Asthma (ARIA) Classes in MASK-air Users.

Background And Objectives: The Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines classify rhinitis as "intermittent" or "persistent" and "mild" or "moderate-severe". To assess ARIA classes in a real-world study in terms of phenotypic differences and their association with asthma.

Methods: We performed a cross-sectional real-world study based on users of the MASK-air® app who reported data for at least 3 different months.

Integrating literature and family insights: exploring the needs of families supporting adults with diabetes.

Introduction: The considerable influence that family members can have on diabetes management is well recognized. Therefore, it is crucial for professionals to acknowledge the impact of the diagnosis on family members. This study aimed to comprehensively identify and understand the needs of family members with an adult diagnosed with diabetes using a two-phased research design.

Effectiveness of Combined Physical and Psychological Interventions on Anxiety and Depression Symptoms in Adult Patients With Chronic Obstructive Pulmonary Disease: a Systematic Review Protocol.

Objective: The objective of this review is to evaluate the effectiveness of combined physical and psychological interventions on anxiety and depression symptoms in adult patients with chronic obstructive pulmonary disease (COPD).

Introduction: By 2030, COPD is expected to be the third-leading cause of death and the seventh in terms of overall health impact, measured in disability-adjusted life years. As with other comorbidities, anxiety and depression disorders influence the prognosis.

Efficacy and safety of pharmacological treatments in inclusion body myositis: a systematic review.

Objective: To identify the best evidence on the efficacy of treatment interventions for inclusion body myositis (IBM) and to describe their safety.

Methods: Systematic review of randomised controlled trials (RCTs) of pharmacological treatments of adults with IBM, conducted according to the Cochrane Handbook, updating a previous Cochrane review. The search strategy was run on Cochrane Neuromuscular Disease Group Specialized Register, CENTRAL, MEDLINE and EMBASE, ClinicalTrials.

Skeletal age assessed by Greulich-Pyle: Intra-observer and inter-observer agreement among male pubertal tennis players.

The assessment of biological maturation is a central topic in pediatric exercise sciences. Skeletal age (SA) reflects changes in each bone of the hand and wrist from initial ossification to the adult state. This study examined intra-observer and inter-examiner agreement is Greulich-Pyle (GP) assessments of SA in 97 male tennis players 8.

Depressive Symptoms and Amyloid Pathology.

Importance: Depressive symptoms are associated with cognitive decline in older individuals. Uncertainty about underlying mechanisms hampers diagnostic and therapeutic efforts. This large-scale study aimed to elucidate the association between depressive symptoms and amyloid pathology.