7 results match your criteria: "Cochin Hotel Dieu University Hospital[Affiliation]"

Background: Advances in vertical take-off and landing (VTOL) technologies may enable drone-like crewed air ambulances to rapidly respond to out-of-hospital cardiac arrest (OHCA) in urban areas. We estimated the impact of incorporating VTOL air ambulances on OHCA response intervals in two large urban centres in France and Canada.

Methods: We included adult OHCAs occurring between Jan.

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Neonatal Outcomes in Extremely Preterm Newborns Admitted to Intensive Care after No Active Antenatal Management: A Population-Based Cohort Study.

J Pediatr

December 2018

Inserm UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé), Center for Epidemiology and Statistics Sorbonne Paris Cité, DHU Risks in Pregnancy, Paris Descartes University, Paris, France; Maternity Unit of Port Royal, Paris Descartes University, Cochin Broca Hotel Dieu Hospitals, DHU Risk in Pregnancy, Cochin Hotel Dieu University Hospital, Assistance Publique des Hopitaux de Paris, Paris, France.

Objective: To evaluate the association between active antenatal management and neonatal outcomes in extremely preterm newborns admitted to a neonatal intensive care unit (NICU).

Study Design: This population-based cohort study was conducted in 25 regions of France. Infants born in 2011 between 22 and 26 weeks of gestation and admitted to a NICU were included.

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Pharmacogenomic biomarkers do not predict response to drotrecogin alfa in patients with severe sepsis.

Ann Intensive Care

January 2018

Critical Care Research Laboratories, Centre for Heart Lung Innovation, St. Paul's Hospital, University of British Columbia, Burrard Building, Rm 166 - 1081 Burrard St, Vancouver, BC, V6Z 1Y6, Canada.

Purpose: To explore potential design for pharmacogenomics trials in sepsis, we investigate the interaction between pharmacogenomic biomarkers and response to drotrecogin alfa (activated) (DrotAA). This trial was designed to validate whether previously identified improved response polymorphisms (IRPs A and B) were associated with an improved response to DrotAA in severe sepsis.

Methods: Patients with severe sepsis at high risk of death, who received DrotAA or not, with DNA available were included and matched to controls adjusting for age, APACHE II or SAPS II, organ dysfunction, ventilation, medical/surgical status, infection site, and propensity score (probability that a patient would have received DrotAA given their baseline characteristics).

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Open access to research data: the two sides of the coin.

Eur J Anaesthesiol

January 2017

From the Department of Anaesthesiology and Perioperative Medicine, Ghent University Hospital - Ghent University, Ghent, Belgium (SDH), and Department of Anaesthesia and Intensive Care, Cochin-Hotel Dieu University Hospital - Paris Descartes University, Paris, France (CMS).

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Antifibrinolytic thereapy.

Thromb Res

January 2014

Cochin-Hôtel Dieu University Hospital, Assistance Publique - Hôpitaux de Paris, Université Paris Descartes, France.

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Introduction: Hyperfibrinolysis is observed during and immediately after major orthopedic surgery. The kinetics and duration of this phase should be defined to adjust the duration of antifibrinolytic treatment with tranexamic acid (TXA).

Objective: We aimed to quantify the duration of postoperative fibrinolysis and to assess the biological impact of TXA administration.

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