1,351 results match your criteria: "Coal Worker's Pneumoconiosis"
Association Between Pulmonary Tuberculosis and Bronchial Anthracosis.
Cureus
November 2024
Pulmonology, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Introduction Anthracosis is black discoloration of the bronchi, which can sometimes cause anthracofibrosis. Usually, exposure to biomass fuel, air pollution, or smoke at the workplace causes it. The objective of the current study was to determine the association between tuberculosis and anthracosis.
View Article and Find Full Text PDFOutcomes of Lung Transplantation in Coal Workers Pneumoconiosis: Analysis of UNOS Database.
Clin Transplant
December 2024
Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Internal Medicine, Emory University Hospital, Atlanta, USA.
Article Synopsis
Anthracosis, epidemiology, gene and cancer: An updated mini-review.
Caspian J Intern Med
October 2024
Student Research Committee, Faculty of Medicine, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Background: It is believed that anthracosis is one of the most important occupational diseases, mainly seen in the residents of industrial areas and coal mine workers. This bronchial disease is more common in Asia's rural areas, particularly in the Middle East. In this study, we examined the epidemiology and genetic factors affecting this disease and its relationship with different types of cancer.
View Article and Find Full Text PDFA Subtle Adversary: Mycobacterium avium-intracellulare Infection of the Surgical Site Years After Bilateral Lung Transplantation.
Cureus
October 2024
Department of Medicine, Division of Pulmonology, University of Kentucky, Lexington, USA.
Article Synopsis
Candidate gene polymorphisms associated with silicosis and coal workers' pneumoconiosis: a systematic review and meta-analysis.
BMC Pulm Med
November 2024
Department of Occupational Medicine and Toxicology, Clinical Center for Interstitial Lung Diseases, Beijing Institute of Respiratory Medicine and Beijing Chao-Yang Hospital, Capital Medical University, No. 8 Workers' Stadium South Road, Chao-Yang District, Beijing, China.
Article Synopsis
Advantages and rational application of indocyanine green fluorescence in pulmonary nodule surgery: a narrative review.
J Thorac Dis
October 2024
Nanjing Nuoyuan Medical Devices Co., Ltd., Nanjing, China.
Background And Objective: The early detection and early treatment of high-risk pulmonary nodules directly affect the long-term survival rate of patients. However, conventional nodule localization methods, such as hook-wire, technetium-99m, and methylene blue are associated with issues such as a high-frequency of complications, low patient tolerance, serious side effects, and inability to identify pigmented lungs. For patients who require segmentectomy, there is often a lack of effective path planning, resulting in insufficient resection margins or excessive loss of lung function.
View Article and Find Full Text PDFA Report of Two Cases of Tuberculosis With Bronchial Anthracofibrosis: Diagnostic Challenges and Therapeutic Approaches.
Cureus
October 2024
Pulmonology and Critical Care, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.
A clinical entity that was reported less than ten years ago, bronchial anthracofibrosis is marked by multifocal bronchial lumen constriction and anthracotic coloring of the bronchial mucosa. There is various etiology associated with "black bronchoscopy". A 47-year-old woman with no known co-morbidities reported having a three-month history of coughing up sputum.
View Article and Find Full Text PDFPsychological morbidity among coal miners compared to other occupations in Appalachia.
J Occup Med Toxicol
October 2024
Division of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Article Synopsis
- Coal miners in Appalachia show higher rates of depression and anxiety compared to other occupations, with 16.3% of surveyed individuals having mining experience.
- The study used comprehensive surveys to assess PTSD, depression, and anxiety among men aged 50 and older, adjusting for various factors like trauma and smoking.
- While coal mining correlated with increased depression (OR 1.6) and anxiety (OR 1.7), it was not directly linked to higher PTSD risk, emphasizing the need for targeted public health interventions for this population.
Current status, trends, and predictions in the burden of coal worker's pneumoconiosis in 204 countries and territories from 1990 to 2019.
Heliyon
October 2024
Shandong Academy of Occupational Health and Occupational Medicine, Shandong First Medical University & Shandong Academy of Medical Sciences, 250062, Jinan, Shandong Province, PR China.
Article Synopsis
- Coal worker's pneumoconiosis (CWP) is a serious lung disease caused by long-term exposure to coal dust, impacting the health and lifespan of miners while also straining economic resources and reducing workforce participation.
- The study analyzes trends and changes in the global impact of CWP from 1990 to 2019, anticipating shifts in how the disease affects miners due to changes in the coal industry.
- By providing a detailed overview of CWP's current and future implications, the study aims to aid countries in creating better health policies and preventive measures for coal miners.
Association of PPARGC1A gene polymorphism and mtDNA methylation with coal-burning fluorosis: a case-control study.
BMC Genomics
September 2024
Key Laboratory of Endemic and Ethnic Diseases, Ministry of Education & Key Laboratory of Medical Molecular Biology of Guizhou Province, & Collaborative Innovation Center for Prevention and Control of Endemic and Ethnic Regional Diseases Co-constructed by the Province and Ministry, Guizhou Medical University, Guiyang, Guizhou, China.
Article Synopsis
- Coal-burning fluorosis is caused by long-term exposure to high-fluoride coal used for heating and cooking, which affects the PPARGC1A gene and its expression levels.
- The study found specific genetic variations (genotypes) at several loci, such as rs13131226 and rs1873532, that significantly increase the risk of developing coal-burning and skeletal fluorosis.
- Increased methylation in the mitochondrial DNA D-loop region is linked to a higher risk of coal-burning fluorosis, highlighting the interaction between genetic factors and environmental exposure in the Guizhou population.
ERCC1 which affects lipids metabolism and actin dynamics in coal workers' pneumoconiosis is a candidate biomarker for early warning and diagnosis.
PLoS One
September 2024
Department of Occupational Diseases, Guiyang Public Health Clinical Center, Guiyang, GuiZhou, China.
Article Synopsis
- * Key findings indicate that specific genotypes of the ERCC1 gene are linked to the progression of CWP, with certain variants showing increased risk for later stages of the disease.
- * ERCC1 is proposed as a potential biomarker for early detection, which could help prevent disease progression and reduce costs for both workers and employers, while also offering targets for future drug development.
Gut microbiome and metabolome profiling in coal workers' pneumoconiosis: potential links to pulmonary function.
Microbiol Spectr
November 2024
NHC Key Laboratory of Pneumoconiosis, Shanxi Key Laboratory of Respiratory Diseases, Department of Pulmonary and Critical Care Medicine, The First Hospital of Shanxi Medical University, Taiyuan, China.
Unlabelled: Coal workers' pneumoconiosis (CWP) is a severe occupational disease resulting from prolonged exposure to coal dust. However, its pathogenesis remains elusive, compounded by a lack of early detection markers and effective treatments. Although the impact of gut microbiota on lung diseases is acknowledged, its specific role in CWP is unclear.
View Article and Find Full Text PDF[Changes of lung function and inflammatory factors in rat models of coal workers' pneumoconiosis].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
August 2024
School of Public Health, Shanxi Medical University, Key Laboratory of Pneumoconiosis, National Health Commission, Key Laboratory of Coal Environmental Pothogenicity and Prevention of Ministry of Education, Taiyuan 030001, China.
Article Synopsis
- The study investigates lung function and inflammatory responses in rat models of coal workers' pneumoconiosis over different time intervals.
- Ninety-six healthy male SD rats were divided into control and dust exposure groups, receiving either saline or various coal dust suspensions, and lung function was monitored at 1, 3, and 6 months post-exposure.
- Results indicated significant declines in forced vital capacity (FVC) and forced expiratory volume (FEV(0.2)) over time in dust-exposed groups, alongside observable changes in lung tissue, confirming that prolonged exposure to coal dust negatively affects lung health.
Caplan Syndrome Mimicking Progressive Massive Fibrosis on CT: A Case Report.
J Korean Soc Radiol
July 2024
Article Synopsis
- - This report discusses a case of Caplan syndrome in a former coal miner, highlighting how it resembled accelerated progressive massive fibrosis.
- - The patient had a long history of coal worker's pneumoconiosis and rheumatoid arthritis, leading to new findings on their CT scans.
- - The paper emphasizes the specific CT scan characteristics of Caplan syndrome that can lead to confusion with progressive massive fibrosis.
An evaluation of pyrite as a component of respirable coal dust.
J Hazard Mater
September 2024
John and Willie Leone Family Department of Energy and Mineral Engineering, College of Earth and Mineral Science, The Pennsylvania State University, University Park, PA 16802, USA. Electronic address:
Article Synopsis
- The study investigates the relationship between coal-pyrites and the production of hydroxyl radicals (•OH), which are harmful reactive species linked to coal worker's pneumoconiosis.
- It assesses the effectiveness of certain chemical additives in reducing •OH production across different pH levels and various solutions, such as tap water and simulated lung fluid.
- Findings reveal that the generation of •OH varies with pyrite composition and surface properties, with some additives like carboxymethyl cellulose showing promise in lowering •OH levels, particularly under aging conditions that enhance radical production.
[Study on the risk factors of coal workers' pneumoconiosis and the mechanism of pyroptosis in peripheral blood].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
July 2024
Office of Occupational Health Quality Control, the Third People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi 830091, China.
Article Synopsis
- The study investigates the risk factors and molecular mechanisms linked to coal workers' pneumoconiosis, aiming to find new diagnostic biomarkers and treatment strategies.
- It includes 142 male participants, categorizing them into different stages of the disease and a control group, while gathering information on health and blood samples.
- The research found significant differences in various health metrics across disease stages, particularly in smoking history, hemoglobin levels, and inflammatory markers like IL-1β and IL-18.
Prevalence of nano-sized coal mine dust in North and Central Appalachian coal mines - Insights from SEM-EDS imaging.
J Hazard Mater
September 2024
Department of Mining Engineering, Indian Institute of Technology (Indian School of Mines), Dhanbad 826004, India.
Article Synopsis
- - The growing incidence of lung diseases among coal miners highlights the urgent need to study respirable coal mine dust (RCMD), particularly focusing on harmful nano-sized particles that are more toxic than larger dust particles.
- - Advanced imaging techniques, like scanning electron microscopy and energy-dispersive spectroscopy, confirm the presence of these nano-sized particles in underground mine samples and reveal their dangerous chemical composition, including elements like silica and iron.
- - The study stresses the importance of recognizing the health risks associated with nano-sized coal dust, urging updates to mining regulations, improved protective measures for miners, and the development of better sampling tools to combat their harmful effects.
Pancreatobiliary Lymphadenopathy: Etiology, Location, and Factors Predicting Good Yield of Endoscopic Ultrasound-guided Biopsy.
Euroasian J Hepatogastroenterol
January 2024
Department of Hepatogastroenterology, Sindh Institute of Urology and Transplantation, Karachi, Sindh, Pakistan.
Article Synopsis
- Pancreatobiliary lymphadenopathy (PBL) can be linked to various benign or malignant conditions, and endoscopic ultrasound (EUS) can help obtain tissue samples for diagnosis.
- A study involving 87 patients revealed that the majority of cases were male (62.1%) with a mean age of 52, and the primary sites of enlarged lymph nodes were in the porta hepatis and peripancreatic areas.
- The findings showed that most cases were due to metastatic adenocarcinoma for neoplastic reasons and tuberculosis for non-neoplastic reasons, with larger lymph node size and satisfactory on-site evaluation linked to better biopsy outcomes.
Research progress on the pathogenesis and prediction of pneumoconiosis among coal miners.
Environ Geochem Health
July 2024
School of Mechatronic Engineering, Jiangsu Normal University, Xuzhou, 221000, Jiangsu Province, People's Republic of China.
Article Synopsis
- - Pneumoconiosis, a lung disease common among coal miners, stems from long-term coal dust inhalation and can lead to severe symptoms like pulmonary fibrosis, increased pain, and higher mortality rates, with no effective treatments available.
- - The disease's pathogenesis is complex, influenced by factors such as coal dust composition, particle size, shape, and concentration, but there is currently no standardized method for early prediction among miners.
- - This review highlights recent research on pneumoconiosis in coal miners, discussing its pathogenesis and the impact of coal dust, as well as introducing diagnostic methods like image analysis and biomarker detection, and addressing challenges in early screening.
[EQ-5D-3L based quality of life for patients of pneumoconiosis combined with tuberculosis and its influencing factors].
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
June 2024
National Institute of Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Article Synopsis
- The study aimed to assess the health-related quality of life for patients suffering from pneumoconiosis combined with tuberculosis in China, involving 951 patients over a period of four years.
- It revealed that the most common type of pneumoconiosis was silicosis with tuberculosis, and a significant portion of patients also had other chronic diseases.
- The results showed lower health utility and self-rating scores for these patients compared to those with pneumoconiosis alone, with notable differences in their quality of life based on urban versus rural residency as well as high instances of pain and discomfort reported.
Article Synopsis
- Anthracosis is a chronic lung disease characterized by the buildup of carbon in the lungs, leading to inflammation and weakened immunity, making patients vulnerable to parasitic infections such as lophomoniasis.
- Early diagnosis and treatment of both anthracosis and lophomoniasis are crucial for improving patient outcomes and preventing complications.
- A case study of a 77-year-old patient highlights the importance of recognizing the symptoms, conducting thorough testing, and treating with bronchodilators, corticosteroids, and antibiotics for effective management of these conditions.
Measuring lung diffusing capacity: an opportunity for improved medical surveillance and disability evaluation of coal miners.
Occup Environ Med
July 2024
Environmental and Occupational Health Sciences Division, University of Illinois Chicago, Chicago, Illinois, USA.
Article Synopsis
- Spirometry is the main test for assessing lung function in coal miners, but it may not fully capture lung impairment; researchers aimed to examine a different measure, called single-breath diffusing capacity for carbon monoxide (D), in former coal miners.
- Analysis of data from over 3,100 former miners revealed that 20.2% showed diffusion impairment, with a notable portion (10%) of those with normal spirometry also affected.
- The study concluded that diffusion impairment is common among former miners, suggesting that incorporating D tests into evaluations can better detect early lung disease alongside traditional spirometry.
Women in Coal Mining-Radiographic Findings of Women Participants in the Coal Workers' Health Surveillance Program 1970-2022.
J Womens Health (Larchmt)
September 2024
Centers for Disease Control and Prevention, Respiratory Health Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, USA.
Article Synopsis
- A study analyzed the work experience and respiratory health of U.S. women coal miners using data from the Coal Workers' Health Surveillance Program (CWHSP) from 1970 to 2022.
- Out of 8,182 women studied, most worked in coal mining for less than 10 years and mainly held non-dusty jobs, with only 0.5% showing signs of pneumoconiosis.
- The findings highlight the importance of understanding women's roles in mining and suggest improvements in gender-specific employment data to enhance their health and working conditions in male-dominated fields.
Histopathological Examination of Lung Necropsy of 11 Patients Who Died Due to COVID-19: A Case Series.
Iran J Pathol
December 2023
Department of Radiology, School of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran.
Article Synopsis
- * Most of the patients had interstitial lymphocytic pneumonitis, with varying severity, and several cases exhibited conditions like anthracosis and hyaline membranes.
- * The findings emphasize the need to monitor various pathological conditions in managing severe COVID-19 infections.
Seronegative Granulomatosis With Polyangiitis With Isolated Lung Lesions: A Case Report.
Cureus
May 2024
Internal Medicine, University of Minnesota, Minneapolis, USA.
Article Synopsis
- Granulomatosis with polyangiitis (GPA) is a rare type of vasculitis that mainly affects small and medium blood vessels, characterized by granulomas particularly in the upper respiratory tract and kidneys.
- A 54-year-old woman presented with symptoms leading to the discovery of GPA, despite being seronegative for common antibodies like ANCA; her lung lesions were identified through imaging and biopsy.
- The patient underwent treatment with intravenous rituximab for six months after diagnoses, which revealed necrotizing granulomatous inflammation.