15 results match your criteria: "Cliniques Universitaires de Saint Luc[Affiliation]"

Article Synopsis
  • This study evaluated the use of motorized spiral enteroscopy (MSE) for performing biliary endoscopic retrograde cholangiopancreatography (ERCP) in patients with altered surgical anatomy at five centers in Europe.
  • Out of 89 enrolled patients, MSE-assisted ERCP had a technical success rate of 54%, while adverse events occurred in 14% of cases, including one serious incident of esophageal perforation.
  • The study was halted in July 2023 due to safety concerns after the MSE device was withdrawn by the manufacturer, indicating potential risks associated with the procedure.
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This review focuses on uterine mesenchymal tumors that are defined on a molecular level by a single and unique genetic alteration, that is somehow necessary and sufficient to allow tumor growth and progression. Although diverse from a clinical, morphological and immunohistochemical point of view, the different entities we are going to talk about share both a simple genomic profile with a low number of chromosomal alterations observed by CGH Array (few deletions, gains or amplifications..

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Introduction: This case report abstract discusses scoliosis, a multifactorial three-dimensional spinal deformity, including lateral curvatures on the frontal plane characterized by Cobb angle measurement, vertebral rotation on the axial plane and sagittal deformity. Scoliosis can be mild, moderate, or severe, and if left untreated, it can lead to further deformity and compromise cardiopulmonary function. Scoliosis is classified into early onset and late onset, with idiopathic scoliosis being the most common form.

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Introduction: Prosthetic joint infection (PJI) is a relatively infrequent occurrence; however, it always poses a significant risk to the patient's functional outcome. The origin of PJI is often a topic of debate. In this case, we present a PJI that resulted from a digestive fistula passing through an iliopsoas abscess, which can be regarded as an unusual consequence of rare conditions.

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Background: Patients with disorders of consciousness (DoC) are a challenging population prone to misdiagnosis with limited effective treatment options. Among neuromodulation techniques, transcutaneous auricular vagal nerve stimulation (taVNS) may act through a bottom-up manner to modulate thalamo-cortical connectivity and promote patients' recovery. In this clinical trial, we aim to (1) assess the therapeutic clinical effects of taVNS in patients with DoC; (2) investigate the neural mechanisms underlying the effects of its action; (3) assess the feasibility and safety of the procedure in this challenging population; (4) define the phenotype of clinical responders; and (5) assess the long-term efficacy of taVNS in terms of functional outcomes.

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Introduction: STELLAR was a Belgian, multicentre, retrospective, observational chart review that described the utilization (number of injections and treatment regimen) and effectiveness of intravitreal aflibercept (IVT-AFL) in patients with anti-vascular endothelial growth factor (VEGF) treatment-naïve neovascular age-related macular degeneration (nAMD) during the first 12 months of IVT-AFL treatment.

Methods: Patients initiating IVT-AFL between July 2013 and July 2017 were included in STELLAR. Primary endpoints were number of visits and IVT-AFL injections, and number of patients who received ≥ 7 versus < 7 IVT-AFL injections during the first 12 months of treatment.

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Article Synopsis
  • Certain changes (mutations) in a gene called CALR can cause diseases like essential thrombocythemia (ET) and primary myelofibrosis (PMF).
  • Scientists created special mice with these CALR mutations to study how they affect blood cell production.
  • These mutated mice had more platelets in their blood and showed issues with heart development when the mutations were present in both copies of the gene.
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Early and Late Factors Impacting Patient and Graft Outcome in Pediatric Liver Transplantation: Summary of an ESPGHAN Monothematic Conference.

J Pediatr Gastroenterol Nutr

September 2017

*Swiss Center for Liver Disease in Children, University Hospitals Geneva, Geneva, Switzerland †Division of Infectious Diseases and the Transplant and Regenerative Medicine Centre, Hospital for Sick Children, University of Toronto, Toronto, Canada ‡Pediatric Nephrology, Imagine Institute, Necker-Enfants Malades Hospital, APHP, Paris Descartes University-Sorbonne Paris Cité, Paris, France §Pediatric Liver Care Center, Cincinnati Children's Hospital, Cincinnati, OH ||Department of Surgery, Ospedale Papa Giovanni XXIII, Bergamo, Italy ¶Faculté de Médecine, University de Nantes, Nantes, France #Pediatric Hepatology, Gastroenterology and Transplantation, Ospedale Papa Giovanni XXIII, Bergamo, Italy **Pediatric Hepatology Unit, Necker Enfants Malades Hospital, Paris, France ††First Department of Pediatrics, Semmelweis University, Budapest, Hungary ‡‡University Tor Vergata, Rome, Italy §§Pediatric Liver GI and Nutrition Centre, King's College Hospital, London, UK ||||Faculty of Medicine, Istanbul University, Istanbul, Turkey ¶¶Institute of Transplant Immunology, FIB-Tx, Hannover Medical School, Germany ##Abdominal Transplant Surgery, University of California San Francisco, San Francisco, CA ***Department of Pediatrics, Karolinska University Hospital, CLINTEC Karolinska Institutet, Stockholm, Sweden †††Pediatric Radiology Department, Hôpital Bicêtre, Hôpitaux Universitaires Paris Sud- Assistance Publique Hôpitaux de Paris, Le Kremlin-Bicêtre, France ‡‡‡Pediatric Hepatology and Liver Transplantation, Hospital Universitario Infantil La Paz, Madrid, Spain §§§Department of Pediatrics, University Children's Hospital Bonn, Bonn, Germany ||||||Center for Cell and Gene Therapy and Texas Children's Cancer Center, Texas Children's Hospital, Houston Methodist Hospital, Baylor College of Medicine, Houston, TX ¶¶¶Pediatric Liver GI and Nutrition Centre, King's College, London, UK ###Seattle Children's Hospital and University of Washington, Seattle, WA ****School of Cancer Sciences ††††Department of Cellular Pathology, Queen Elizabeth Hospital, University of Birmingham, Birmingham, UK ‡‡‡‡The European Transplant Registry, APHP Paul Brousse Hospital, Villejuif, France §§§§Liver Unit, Birmingham Children's Hospital, Birmingham, UK ||||||||Department of Pediatric Hematology/Oncology and Integrated Research and Treatment Center for Transplantation, Hannover Medical School, Germany ¶¶¶¶Hillman Center for Pediatric Transplantation, Children's Hospital of Pittsburgh, Pittsburgh, PA ####Department of Medicine, Surgery and Dentistry "Scuola Medica Salernitana", Section of Pediatrics, University of Salerno, Baronissi, Italy *****Bambino Gesu Children's Hospital, Rome, Italy †††††Department of Pediatric Gastroenterology, Hepatology, and Nutrition, Ege University, Izmir, Turkey ‡‡‡‡‡Pediatric Surgery and Transplantation Unit, Cliniques Universitaires de Saint-Luc, Université Catholique de Louvain, Brussels, Belgium §§§§§ISMETT, University of Pittsburgh Medical Center, Palermo, Italy ||||||||||The Children's Memorial Health Institute, Warsaw, Poland ¶¶¶¶¶Divisions of Abdominal and Transplant Surgery, Faculty of Medicine and University Hospitals Geneva, Geneva, Switzerland #####University of Salerno, Baronissi, Italy ******King's College Hospital, Institute of Liver Studies, London, UK ††††††Department for Pediatric Kidney, Liver and Metabolic Disease, Division of Pediatric Gastroenterology and Hepatology, Hannover Medical School, Hannover, Germany.

As pediatric liver transplantation comes of age, experts gathered to discuss current paradigms and define gaps in knowledge warranting research to further improve patient and graft outcomes. Identified areas ripe for collaborative research include understanding the molecular and cellular mechanisms of tolerance and the role of donor-specific antibodies, considering ways to expand donor pool, minimizing long-term side effects of immunosuppression, and fine-tuning surgical techniques to minimize biliary and vascular complications.

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Objective: To compare in a multicenter randomized controlled trial the benefits in terms of anxiety regulation of a 15-session single-component group intervention (SGI) based on support with those of a 15-session multiple-component structured manualized group intervention (MGI) combining support with cognitive-behavioral and hypnosis components.

Methods: Patients with nonmetastatic breast cancer were randomly assigned at the beginning of the survivorship period to the SGI (n = 83) or MGI (n = 87). Anxiety regulation was assessed, before and after group interventions, through an anxiety regulation task designed to assess their ability to regulate anxiety psychologically (anxiety levels) and physiologically (heart rates).

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On the accuracy of adults' auditory perception of normophonic and dysphonic children's personality.

Logoped Phoniatr Vocol

October 2015

c Université de Liège, Département de psychologie: cognition et comportement, Unité de la voix , Liège , Belgium.

We investigated the accuracy of auditory inferences of personality of Belgian children with vocal fold nodules (VFN). External judges (n = 57) were asked to infer the personality of normophonic (NP) children and children with VFN (n = 10) on the basis of vowels and sentences. The auditory inferred profiles were compared to the actual personality of NP and VFN children.

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[Central nervous system involvement in Wegener's granulomatosis].

Rev Med Interne

November 2008

Service de médecine interne générale, cliniques universitaires de Saint-Luc, université catholique Louvain, avenue Hippocrate, 1200 Bruxelles, Belgique.

Introduction: Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis associated with c-ANCA antibodies. The involvement of the central nervous system in WG is uncommon and usually caused by in situ vasculitis, intracranial granuloma formation or contiguous invasion from extracranial sites.

Case Report: Here, we report on a tumour-like expansion of a severe nasosinusal WG into the brain, which was confirmed by brain biopsy examination.

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[Safety and efficacy of multiple subpial transections: report of a consecutive series of 30 cases].

Neurochirurgie

May 2008

Département de neurochirurgie, centre de référence pour l'épilepsie pharmacorésistante, cliniques universitaires de Saint-Luc, université catholique de Louvain, avenue Hippocrate 10, 1200 Bruxelles, Belgique.

Purpose: To present our results using multiple subpial transections (MST) for the treatment of pharmacologically refractory epilepsy (PRE) with epileptogenic foci in eloquent areas.

Method: Between January 2003 and March 2006, we treated 33 patients with PRE with epileptogenic foci in eloquent areas by MST "in rays", either isolated (MSTs group) or completing resection or disconnection of other cortical areas (MST+ group). Our first 30 patients had a follow-up of at least 24 months: eight in the MSTs group and 22 in the MST+ group.

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["Facial graft": about the first facial allotransplantation of composite tissues].

Ann Chir Plast Esthet

October 2007

Département de Morphologie Expérimentale et Service de Chirurgie Plastique et Reconstructrice, Université Catholique de Louvain et Cliniques Universitaires de Saint-Luc, Bruxelles, Belgique.

The first facial allograft was realised in Amiens 2005 November 27th. Breaking the technical limits of the so called possible and in appearance transgressing some cultural forbidden in organ transplantation, this resolutely innovative intervention open more than new perspective in the surgery of the reconstruction after disfigurement, but also a wide field of scientific investigations about dynamic and meaning of the facial function. Obviously, it also deals with numerous ethical and medical problems.

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Genes and metals: a deadly combination.

Acta Gastroenterol Belg

May 2005

Cliniques Universitaires de Saint-Luc, Département de Pédiatrie, Bruxelles.

Wilson's disease is an autosomal recessive disease of copper metabolism, with an estimated prevalence of 1:30000. The most common presentations of WD are liver disease and neurological disturbance. For many years the diagnosis was based on the results of several clinical and biochemical tests, for which several limitations had been reported.

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