15 results match your criteria: "Clinics Hospital of University of Sao Paulo[Affiliation]"

Functional Free Muscle Transfer for Reconstruction of Traumatic Adult Brachial Plexus Injuries.

Hand Clin

May 2024

Hand Surgery and Reconstructive Microsurgery Group of the Institute of Orthopedics and Traumatology, Clinics Hospital of University of Sao Paulo, São Paulo, Brazil.

Article Synopsis
  • Traumatic brachial plexus injury is primarily treated with functional free muscle transfer (FFMT), aiming to restore elbow flexion as the main goal, along with shoulder stability and hand movement.* -
  • The article reviews existing literature on the effectiveness of FFMT for adults suffering from these injuries.* -
  • It also offers surgical technical recommendations to optimize functional outcomes for patients undergoing FFMT after traumatic brachial plexus injuries.*
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Introduction And Hypothesis: Enhanced recovery after surgery (ERAS) evidence-based protocols for perioperative care can lead to improvements in clinical outcomes and cost savings. This article aims to present consensus recommendations for the optimal perioperative management of patients undergoing urogynecological surgery.

Methods: A review of meta-analyses, randomized clinical trials, large nonrandomized studies, and review articles was conducted via PubMed and other databases for ERAS and urogynecological surgery.

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Computed tomography angiography and microsurgical flaps for traumatic wounds: What is the added value?

Clin Hemorheol Microcirc

October 2021

Hand Surgery and Reconstructive Microsurgery Group of the Institute of Orthopedics and Traumathology, Clinics Hospital of University of Sao Paulo, São Paulo, Brazil.

Background: Microsurgical flaps are widely used to treat complex traumatic wounds of upper and lower limbs. Few studies have evaluated whether the vascular changes in preoperative computed tomography angiography (CTA) influence the selection of recipient vessel and type of anastomosis and the microsurgical flaps outcomes including complications.

Objective: The aim of this study was to evaluate if preoperative CTA reduces the occurrence of major complications (revision of the anastomosis, partial or total flap failure, and amputation) of the flaps in upper and lower limb trauma, and to describe and analyze the vascular lesions of the group with CTA and its relationship with complications.

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Introduction: The traumatic lesions of the brachial plexus in adults are devastating injuries causing continuous severe functional impairment for both work and daily living activities. The restoration of elbow flexion is one of the most important movements for patient recovery to previous activities. Free gracilis muscle transfer has good outcomes for cases with late presentation or as a rescue surgery to regain elbow flexion, however, bad results are present in all cohorts with insufficient recovery of muscle strength for elbow flexion.

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Background: Myasthenia gravis (MG) is a challenge for anesthesia management. This report shows that the use of rocuronium-sugammadex is not free from flaws and highlights the importance of cholinesterase inhibitors management and neuromuscular block monitoring in the perioperative period of myasthenic patients.

Case Presentation: Myasthenic female patient submitted to general balanced anesthesia using 25 mg of rocuronium.

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Study of the formulation optimization and reusability of a MAGAT gel dosimeter.

Phys Med

July 2019

Physics Department, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto, University of São Paulo, Av. Bandeirantes 3900, 14040-901, Monte Alegre, Ribeirão Preto, SP, Brazil; Radiotherapy Service, Clinics Hospital of University of São Paulo Medical School at Ribeirão Preto, Av. Bandeirantes 3900, 14040-900, Monte Alegre, Ribeirão Preto, SP, Brazil. Electronic address:

Article Synopsis
  • The study focuses on optimizing a methacrylic acid gelatine and tetrakis (hydroxymethyl) phosphonium chloride (MAGAT) gel dosimeter to ensure both effective radiation measurement and cost efficiency.
  • Various concentrations of the components in the dosimeter were tested to achieve a reliable dosimetric response, with the final formulation showing good linearity and consistency across different radiation doses.
  • The optimized MAGAT gel dosimeter demonstrated a usable sensitivity and can be reused after irradiation, though its sensitivity decreases by 15% after the initial use.
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Do two venous anastomoses decrease venous thrombosis during limb reconstruction?

Clin Hemorheol Microcirc

November 2019

Hand Surgery and Reconstructive Microsurgery Group of the Institute of Orthopedics and Traumathology, Clinics Hospital of University of Sao Paulo, São Paulo, Brazil.

Background: The optimal number of veins to be anastomosed in perforator flaps for limb reconstruction and its influence on the results remain controversial. Venous thrombosis of microvascular anastomoses is a commonly recorded complication in soft tissue reconstruction.

Objective: To evaluate the effect of two venous anastomoses in the incidence of venous thrombosis for limb reconstruction using anterolateral thigh (ALT) microsurgical free flaps.

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This study aimed to evaluate the relationship between posturography, clinical balance, and executive function tests in Parkinson´s disease (PD). Seventy-one people participated in the study. Static posturography evaluated the center of pressure fluctuations in quiet standing and dynamic posturography assessed sit-to-stand, tandem walk, and step over an obstacle.

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Regurgitation of Undigested Food: What is Your Diagnosis?

Dysphagia

April 2016

Department of Otorhinolaryngology, Clinics Hospital of University of Sao Paulo, School of Medicine, Av. Eneas de Carvalho Aguiar, 255, 6o. andar, São Paulo, CEP 05403-000, Brazil.

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Article Synopsis
  • Amyotrophic Lateral Sclerosis (ALS) is a lethal neurodegenerative condition characterized by motor neuron death, leading to muscle weakness and respiratory failure; the most common form is sporadic and not inherited.
  • Research efforts to develop treatments have largely failed as they rely on animal models with specific gene mutations that do not represent sporadic ALS.
  • Using human induced pluripotent stem cell (hiPSC)-derived motor neurons from sporadic ALS patients, the study identified key dysregulated genes and highlighted the important role of mitochondrial function in the disease’s progression, suggesting potential pathways for future research and therapeutic strategies.
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Unlabelled: The extrinsic ectropion is a condition with low prevalence characterized by an ectropion with normal eyelid and anatomy unchanged and the cause is found in tissues adjacent orbits. There are not many studies in the literature regarding their treatment, especially without addressing the eyelid respecting its anatomical integrity.

Purpose: To evaluate the outcome of 8 extrinsic ectropions secondary to facial burns treated with facial suspension technique.

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Background: Clobazam has been used in clinical practice as an adjunctive treatment for diverse seizure types and epilepsy syndromes. We evaluated the efficacy and safety of clobazam in a large sample of patients with refractory epilepsy at a tertiary pediatric center.

Methods: We retrospectively reviewed patients treated with clobazam between January 2001 and July 2013 who had a follow-up visit at least one month after starting clobazam.

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Use of itraconazole in the treatment of mucocutaneous leishmaniasis: a pilot study.

Int J Infect Dis

August 2001

Department of Infectious and Parasitic Diseases, Clinics Hospital of University of São Paulo, School of Medicine, São Paulo, Brazil.

Objective: Mucocutaneous leishmaniasis is widely distributed in Brazil, with Leishmania (Viannia) braziliensis being the major etiologic agent. The currently recommended therapy is limited by its parenteral use, high toxicity, and variable efficacy. A clinical pilot study was conducted to analyze itraconazole as an oral alternative for the treatment of mucocutaneous leishmaniasis.

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Twenty three infants with neonatal seizures were followed prospectively to a mean age of 11 months. Only 2 were pre-term and birth weight ranged from 1700 to 4230 grams, with 17 male and 6 female infants. Hypoxic-ischemic encephalopathy was the most common etiology (82.

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