6 results match your criteria: "Clinical research and Innovation Department (DRCI)[Affiliation]"
What competencies are needed to develop collaboration between general practitioners and pharmacists through initial interprofessional training? An analysis of training needs through a qualitative occupational didactic approach.
BMC Med Educ
August 2024
ACCePPT Research Laboratory, University Clermont Auvergne and Clinical Research and Innovation Department (DRCI), Clermont-Ferrand University Hospital, Clermont-Ferrand, France.
Article Synopsis
- The study emphasizes the importance of collaborative practice in primary health care, especially between general practitioners (GPs) and community pharmacists (CPs) in France.
- Identifying training needs for last-year GP and CP students is crucial for fostering effective interprofessional collaboration, which has been challenging to develop.
- A framework was created to define key competencies and communication tools needed for collaboration, ultimately leading to better care for patients through structured interactions and exchanges between GPs and CPs.
Abatacept in early polymyalgia rheumatica (ALORS): a proof-of-concept, randomised, placebo-controlled, parallel-group trial.
Lancet Rheumatol
December 2023
Université de Bretagne Occidentale (Univ Brest), CHU Brest, INSERM (U1227), Brest, France.
Background: Medium-dose glucocorticoids can improve symptoms in nearly all patients with polymyalgia rheumatica. According to its good safety profile, abatacept could be used instead of glucocorticoids in early polymyalgia rheumatica. We aimed to determine whether the efficacy of abatacept is sufficient to justify larger studies in early polymyalgia rheumatica.
View Article and Find Full Text PDF[F]FDG PET/CT for therapeutic assessment of Abatacept in early-onset polymyalgia rheumatica.
Eur J Nucl Med Mol Imaging
April 2024
Nuclear Medicine Department, University Hospital, Brest, France.
Purpose: Evaluate the benefit of 2-deoxy-2-[18F]-fluoro-D-glucose ([F] FDG) positron emission tomography/computed tomography (PET/CT) for the therapeutic assessment of Abatacept (ABA) as first-line therapy in early-onset polymyalgia rheumatica (PMR) patients.
Methods: This was an ancillary study of ALORS trial (Abatacept in earLy Onset polymyalgia Rheumatica Study) assessing the ability of ABA versus placebo to achieve low disease activity (C-Reactive Protein PMR activity score (CRP PMR-AS) ≤ to 10) without glucocorticoid (GC) at week 12 in patients with early-onset PMR. The patients underwent [F] FDG PET/CT at baseline and after 12 weeks of treatment.
Stress management in obesity during a thermal spa residential programme (ObesiStress): protocol for a randomised controlled trial study.
BMJ Open
December 2019
Université Clermont Auvergne, INRA, CRNH, University Hospital of Clermont-Ferrand, CHU Clermont-Ferrand, Unit of Human Nutrition, Clermont-Ferrand, France.
Introduction: Stress and obesity are two public health issues. The relationship between obesity and stress is biological through the actions of stress on the major hormones that regulate appetite (leptin and ghrelin). Many spa resorts in France specialise in the treatment of obesity, but no thermal spa currently proposes a specific programme to manage stress in obesity.
View Article and Find Full Text PDFEffects of a short residential thermal spa program to prevent work-related stress/burnout on stress biomarkers: the ThermStress proof of concept study.
J Int Med Res
October 2019
University Hospital of Clermont-Ferrand, CHU Clermont-Ferrand, Clinical research and Innovation Department (DRCI), Biostatistics Unit, Clermont-Ferrand, France.
Objective: Work-related stress is a public health issue. Stress has multiple physical and psychological consequences, the most serious of which are increased mortality and cardiovascular morbidity. The ThermStress protocol was designed to offer a short residential thermal spa program for work-related stress prevention that is compatible with a professional context.
View Article and Find Full Text PDFA 96-hour continuous wound infiltration with ropivacaine reduces analgesic consumption after liver resection: A randomized, double-blind, controlled trial.
J Surg Oncol
January 2019
Oncology Surgery Department, Centre Léon Bérard, Lyon, France.
Background: Continuous wound infiltration (CWI) with local anesthetics to reduce morphine consumption in postoperative pain management after open liver resection in patients with cancer.
Methods: This single-center randomized double-blind study allocated patients requiring resection of liver metastases to receive a 3.75 mg/mL ropivacaine (ROP) infiltration, followed by a 2 mg/mL ROP CWI, or placebo (P) for 96 hours.