Preoperative prediction of lung function in pneumonectomy by spirometry and lung perfusion scintigraphy.

Introduction: Nowadays an increasing number of lung resections are being done because of the rising prevalence of lung cancer that occurs mainly in patients with limited lung function, what is caused by common etiologic factor - smoking cigarettes. Loss of lung tissue in such patients can worsen much the postoperative pulmonary function. So it is necessary to asses the postoperative pulmonary function especially after maximal resection, i.

Ultrasound evaluation of uterine scar after cesarean section.

Introduction: The rate of attempted vaginal birth after previous cesarean delivery has decreased, while the success rate of such births increased. Advances in surgical techniques, the development of anesthesiology services, particularly endotracheal anesthesia, very quality postoperative care with cardiovascular, respiratory and biochemical resuscitation, significantly reduce maternal mortality and morbidity after cesarean section. Progress and development of neonatal services, and intensive care of newborns is enabled and a high survival of newborn infants.

Detection methods of immunoglobulin IgG in CSF and serum.

Introduction: This study represents a new approach to the extended analysis of correlation of findings of oligoclonal bands on gels and the level of intrathecal synthesis of immunoglobulin G in the central nervous system. Previous studies have shown that there is no correlation at this level as well as the number of tape or finding does not correlate with the forecast effect of therapy or patient outcome.

Aims Of The Study: To determine the correlation of level of immunoglobulins IgG in CSF with the number of oligoclonal bands on the gel.

The influence of inflammatory markers and CRP predictive value in relation to the target hemoglobin level in patients on chronic hemodialysis.

Unlabelled: The aim of this study was to determine the influence of inflammatory markers, predictive values of CRP and target hemoglobin (Hb) in patients on chronic hemodialysis.

Material And Methods: Made is a cross-sectional study of inflammatory agents serum levels-CRP, fibrinogen and ferritin before hemodialysis in 114 patients divided into two groups according to the achieved or unachieved target hemoglobin level in the Cantonal Hospital in Zenica.

Results: The 57 patients (test group) did not reached the target hemoglobin in the range from 10-12 g/dl and CRP values were significantly higher compared to the control group (57 patients) who had reached targeted hemoglobin values.

Improved glycaemic control with insulin glargine as part of a basal-bolus regimen in T2DM patients inadequately controlled on premixed therapy.

Objectives: Monitoring efficacy of insulin glargine administered to patients with diabetes mellitus type 2 (DMT2) in combination with rapid-action insulin and analogues, where the hitherto fixed-mixture insulin therapy failed to achieve a satisfactory glycaemic control (HbA1c < 7%) following a six-month fixed-mixture insulin therapy.

Design: Open, observational, multicentric, non comparative, prospective product registry.

Results: 9-month prospective observational study recruited DMT2 patients previously uncontrolled on premixed insulin (HbA1c > 7%).

Comparison of two and three dimensional transthoracic versus transesophageal echocardiography in evaluation of anatomy and pathology of left atrial apendage.

Objective: Our objective was the comparison of combined utility of two-dimensional (2D) transthoracic echocardiography (TTE) and three-dimensional (3D) TTE versus 2D and 3D transesophageal echocardiography (TEE) in evaluation of anatomy of the left atrium appendage (LAA) and for clot formation in LAA.

Background: 2DTEE as semi-invasive method has been for a long time used to visualize the LAA. Improved echocardiography technology has increasingly improved visualization of LAA by 2DTTE and 3DTTE in many patients and decreased the need for TEE performance.

The kinetics of virological and biochemical responses in the treatment of chronic hepatitis C by dual antiviral therapy.

Introduction: Infection with hepatitis C is often manifested by a mild clinical course, and in many patients it is revealed incidentally, during routine laboratory ests. Progression of the disease often takes 10-20 years with specified high risk of fibrosis and hepatocellular carcinoma.

Material And Methods: The group of subjects with chronic liver disease of viral C etiology was consisted of 50 patients of both sexes, 38 (75%) were male and 13 (25%) females, aged 20-65 years.

Ultrasound evaluation of uterine scar after Cesarean section and next birth.

Introduction: Cesarean section (Sectio Caesarea) is a surgical method for the completion of delivery. After various historical modifications of operative techniques, modern approach consists in the transverse dissection of the anterior wall of the uterus. The rate of vaginal birth after cesarean section was significantly reduced from year to year, and the rate of repeated cesarean section is increased during the past 10 years.

The secondary composite temporoparietal lobe-modification.

Orbital defects after malignant tumor removal represent a major problem for satisfactory reconstruction. Treatment and surgical reconstruction according to the regular surgical protocol improves with each new case contributing to continuous improvement of surgical techniques in order to achieve better reconstruction of the defect. In our modification in 20 patients there was presented a new method of reconstruction of the defect where the orbits included also a part of the muscle (sternocleidomastoid muscle) for better stabilization at the desired position on the immediate ocular prosthesis installation site in order to quickly overcome the postoperative defect after orbital exenteration.

Brucella endocarditis in prosthetic valves.

Conflict Of Interest: none declared.

Introduction: Brucella endocarditis (BE) is a rare but severe and potentially lethal manifestation of brucellosis. Pre-existing valves lesions and prosthetic valves (PV) are favorable for BE.

The development of infectology in bosnia and herzegovina, with special emphasis on the development and history of infectious clinic, clinical center of sarajevo university.

none declared There is a relatively low amount of historical data about development of infectology in Bosnia and Herzegovina, but that does not mean that these medical disciplines didn't have important events and actors that are important for the development of this medical discipline in B&H. In this review we intent to show your several characteristic events and important persons, which left a lasting impression in the development of infectology service in BIH and especially in Sarajevo. Development center for this discipline was in Sarajevo.

Asthma and Chronic Obstructive Pulmonary Disease (COPD) - Differences and Similarities.

Bronchial asthma and COPD (chronic obstructive pulmonary disease) are obstructive pulmonary diseases that affected millions of people all over the world. Asthma is a serious global health problem with an estimated 300 million affected individuals. COPD is one of the major causes of chronic morbidity and mortality and one of the major public health problems worldwide.

Interferon treatment of multiple sclerosis.

Introduction: IN THE TREATMENT OF MULTIPLE SCLEROSIS (MS) DIFFER: treatment of relapse, treatment slow the progression of the disease (immunomodulators and immunosuppression), and symptomatic treatment.

The Aim: The aim of this study is to analyze the application of interferon therapy in the treatment of MS-E: Process the disease, patients with multiple sclerosis who have passed the commission for multiple sclerosis at the Neurology Clinic of Clinical Center of Sarajevo University as a reference center for referral to the Commission for multiple sclerosis from the Federal Ministry of Health in 2009 year in terms of total number examined, gender differences, diagnostic tests (MRI, CSF, EP), neurological findings and EDSS scores. Provide a section through the continuous support and education of patients during the introduction Betaferon in therapy with the goal of education for self-use and reduce the incidence of side effects of interferon therapy.

Effects of conservative treatment for osteoporotic thoracolumbal spine fractures.

Introduction: Osteoporosis has a significant role in the etiology of thoracolumbal spinal fractures in older patients. It is the segment where the relatively immobile thoracic segment transfers into a mobile lumbar spine. The clinical picture is always with the back pain after minimal trauma or sometimes even without injury.

Erectile dysfunction as a complication after treatment of prostate cancer.

Introduction: Treatment of localized prostate cancer refers to two basic modes which are the radical retro pubic prostatectomy and external radiotherapy. However, according to most authors, radical prostatectomy is the gold standard for long-term survival.

Objective: To determine the occurrence of erectile dysfunction after radical operative treatment and irradiation therapy.

How the application of human immunoglobulin in the treatment of myasthenia crisis changed the outcome of the disease.

Introduction: Myasthenia gravis (MG) is an autoimmune disease characterized by weakness and fluctuating pathological tiredness of cross-striped muscle with improvement after rest.

Goal: To compare the outcomes of treatment in myasthenic crisis therapy and conventional therapy with high doses of human immunoglobulin. Epidemiological research, mainly retrospective, partly prospective, descriptive-analytical and clinical-application nature, was carried out on Neurology Clinic Clinical Center University of Sarajevo in the period from January 1st 2002 to December 31st 2008.

The most frequent psychiatric disorders registered at day hospital of psychiatric clinic in sarajevo during 2006-2007.

NONE DECLARED Day Hospital is an alternative to inpatient treatment as a transition from hospital to outpatient type of treatment, especially for those patients who cannot quickly return to the family, and patients who are unable to leave the usual social contacts so to them the hospitalization will pose a great mental risk. The aim of the research is to determine the structure of psychiatric morbidity, as well as demographic features and duration of hospitalization in patients treated at a Day Hospital of Psychiatric Clinic in Sarajevo during the period 2006-2007. The survey is conducted at the Psychiatric Clinic, Clinical Center of Sarajevo University as retrospective, based on observations of certain variables (gender, age, hospitalization duration), and the number of diagnosis.

Efficiency and safety of radioactive iodine I-131 in treatment of thyroid disease.

Thyroid gland is the largest endocrine gland in the body. The thyroid gland produces hormones that regulate the metabolism rate, affect the growth and many functions of various organ systems. Nuclear medicine technique is very useful diagnostic tool in detecting thyroid disease.

Surgical treatment of pleural empyema according to disease stage.

Unlabelled: Para pneumonic effusions are often complications of bacterial pneumonia, occurring in 5-50% patients and in 15% cases it can progress into pleural empyema. Pleural empyema treatment includes drainage of pus, re-expansion of lung by using appropriate antibiotics. Surgical treatment covers implementation of certain thoracic drainage modifications, use of VATS techniques and thoracotomy with pleura decortications.

Possibilities of computer assisted tomography (CT) in evaluation of lung cancer operability.

As is well known, surgical treatment is the most effective therapy for non-small cell lung cancer, although only a small number of patients are suitable for this type of treatment (25%-30%). The outcome of operative treatment and prognosis greatly depends on accurate preoperative diagnostic process using the TNM classification. Until now, different diagnostic methods are used in the preoperative staging of this severe illness, including computer assisted tomography which acquired a leading role.

Incidence of secondary vascular complications after stroke.

Unlabelled: Stroke is a clinical syndrome characterized by the sudden occurrence of a permanent focal neurological deficit. The most common causes of death are transtentorial herniation, pneumonia, pulmonary embolism and heart disease. According to literature data, pulmonary embolism (PE) is responsible for 5% of deaths after stroke.

Somatosensory evoked cerebral potentials (SSEP) in multiple sclerosis.

Introduction: Neurological findings are the main criteria for making the diagnosis of multiple sclerosis, including head and spine MRI, CSF findings and evoked potentials.

Objective: Investigate and observe correlation in SSEP especially wave P22 in group of healthy examiners, as well on those suffering multiple sclerosis. Present Evoked potentials clinical application benefits in Multiple sclerosis diagnostic procedures used in Neurological Clinic, Clinical Center University of Sarajevo.

Role of transrectal ultrasonography in evaluting azoospermia causes.

Infertility is a term with which we define lack of pregnancy among sexual partners within one year of regular intercourses without use of contraceptives. The term primary infertility includes lack of any previous pregnancy, while secondary infertility is a current infertility with previous successful pregnancy. Azoospermia is an inability to produce spermatozoids in testicles or represents normal production of the spermatozoids but the obstacle is somewhere in the ejaculatory paths.

Randomized phase II study of induction chemotherapy with gemcitabine plus cisplatin followed by sequential radiotherapy versus radiotherapy alone in patients with stage III non-small cell lung cancer.

Purpose: This randomized phase II trial was conducted to compare the overall response rate (ORR) of gemcitabine plus cisplatin combination followed by sequential radiotherapy (RT) (arm A) versus RT alone (arm B) in chemonaive patients with stage IIIA or IIIB non-small cell lung cancer (NSCLC). Secondary objectives were to evaluate time to progressive disease (TTPD), overall survival, and treatment tolerability in both arms.

Patients And Methods: Eligible patients were required to have stage IIIA or stage IIIB NSCLC, no previous chemotherapy, ECOG performance status of 0-2, bidimensionally measurable disease, and age 18 to 75 years.