368 results match your criteria: "Clinical Research and Public Health[Affiliation]"

Article Synopsis
  • HTG-AP hospitalizations are on the rise in the US, particularly affecting Hispanic patients more than non-Hispanic whites, with both groups experiencing increased hospitalization rates.
  • The study analyzed data from the National Inpatient Sample from 2016 to 2020, finding that HTG-AP accounted for 5.9% of all acute pancreatitis cases, with significantly higher rates in the Hispanic population.
  • Despite similar clinical outcomes between the groups, Hispanic patients faced substantially higher hospital costs, totaling an excess of over $26 million compared to their non-Hispanic white counterparts.
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Article Synopsis
  • * Dienogest (DNG), a selective progestin, is commonly used for treating adenomyosis, but a specific case raised concerns about its safety.
  • * A 42-year-old woman on dienogest therapy suffered from dangerous uterine bleeding leading to hemorrhagic shock and a pulmonary embolism, ultimately requiring emergency surgery and anticoagulation treatment, suggesting a link between her condition, the medication, and the complications.
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Currently, risk stratification calculators for acute pancreatitis (AP) can at best predict acute pancreatitis mortality at 12 hours from the presentation. Given the severe morbidity associated with AP, the identification of additional prognostic indicators, which may afford earlier prediction in length of stay (LOS) and mortality, is desired. Metabolic acidosis can be a prognostic marker for the severity of AP, and venous bicarbonate can reliably and accurately be substituted for arterial base deficit to detect metabolic acidosis.

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Cutis verticis gyrata in a patient with acromegaly: an unusual case and review of literature.

Dermatol Online J

June 2024

Laboratory of Epidemiology, Clinical Research and Public Health, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, University of Mohammed 1st, Oujda, Morocco.

Article Synopsis
  • * Cutis verticis gyrate (CVG) is a rare skin complication seen in some acromegaly patients, characterized by the abnormal growth of scalp skin resulting in folds and furrows.
  • * Treatment involves managing growth hormone and IGF1 levels through surgery or injections, and the diagnosis of CVG is primarily clinical, requiring no imaging.
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Background: Adolescents and young adults (AYAs) with cancer are at risk of poor psychosocial outcomes. AYAs grew up with the internet and digital technology, and mobile Health (mHealth) psychosocial interventions have the potential to overcome care access barriers.

Objective: This pilot randomized controlled trial (RCT) aimed to establish the feasibility, acceptability, and preliminary efficacy of a fully automated mobile app version of the Promoting Resilience in Stress Management intervention (mPRISM).

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Article Synopsis
  • The study focuses on the rising aging population in France and Western Europe, specifically individuals aged 85 and older, and their mortality risk in trauma centers' ICUs.
  • Conducted from 2013 to 2022, the research analyzed 365 severely injured older patients in 14 ICU trauma centers, assessing their frailty and other clinical variables.
  • High mortality rates were found, with 43.5% in the ICU and 45.5% at 30 days, linked to factors like traumatic brain injury and severe hemorrhage, highlighting the need for early geriatric interventions to improve patient outcomes.
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Background: Approximately 20-50% of adolescent and young adult-aged childhood cancer survivors (AYA-CCS) experience sexual dysfunction (SD), although this healthcare need is widely underrecognized. Previous research from both AYA-CCS patients and their providers report that SD needs are unaddressed despite patient desires for SD discussions to be incorporated as part of their care. Patients and providers agree that standardized use of a patient-reported outcome measure may facilitate SD discussions; an SD screening approach was developed with patient and provider input.

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Robotic-Assisted and Laparoscopic Bariatric Surgeries Still Have Clinically Comparable Outcomes.

Obes Surg

August 2024

Department of Surgery, School of Medicine, Creighton University, 7710 Mercy Road, Education Building, Suite 501, Omaha, NE, 68124, USA.

Purpose: Bariatric surgery is considered the main treatment option for patients with severe obesity. The objective of our study is to compare intra- and postoperative outcomes between the robotic and laparoscopic approaches within the sleeve gastrectomy (SG), duodenal switch (DS), and Roux-en-Y gastric bypass (RYGB).

Materials And Methods: The data from the MBSAQIP were collected for patients who underwent SG, DS, and RYGB between 2015 and 2021.

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Purpose: Treatment strategies for osteosarcoma evolving between 1970 and 1999 improved 5-year survival and continue as standard of care today. This report evaluates the impact of these evolving therapies on long-term health outcomes.

Methods: Five-year survivors of childhood osteosarcoma in CCSS treated from 1970 to 1999 were evaluated for late (>5 years from diagnosis) mortality, chronic health conditions (CHCs), and health status using piecewise-exponential and logistical models.

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Video consent significantly improves patient knowledge of general surgery procedures.

Surg Endosc

August 2024

Department of Surgery, Creighton University School of Medicine, Creighton University, 7710 Mercy Road, Education Building, Suite 501, Omaha, NE, 68124, USA.

Introduction: Informed consent is essential in ensuring patients' understanding of their medical condition, treatment, and potential risks. The objective of this study was to investigate the impact of utilizing a video consent compared to standard consent for patient knowledge and satisfaction in selected general surgical procedures.

Methods And Procedures: We included 118 patients undergoing appendectomy, cholecystectomy, inguinal hernia repair, and fundoplication at two hospitals in Omaha, NE.

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Objectives: To evaluate the association between 3 ECT quality measures (seizure duration, Postictal Suppression Index [PSI], and heart rate response) and therapeutic compliance as indicated by transitioning from acute to continuation to maintenance phases of ECT.

Methods: This was a retrospective chart review of patients who received ECT between July 2016 and July 2019. ECT quality measures were lagged by 1 ECT session to examine the effect of the prior session's quality measure on progressing to a higher ECT phase at the subsequent ECT session.

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Background: Approximately 20-50% of adolescent and young adult-aged childhood cancer survivors (AYA-CCS) experience sexual dysfunction (SD), although this healthcare need is widely underrecognized. Previous research from both AYA-CCS patients and their providers report that SD needs are unaddressed despite patient desires for SD discussions to be incorporated as part of their care. Patients and providers agree that standardized use of a patient-reported outcome measure may facilitate SD discussions; an SD screening approach was developed with patient and provider input.

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Apoplexy of a giant clival ectopic prolactinoma: A very rare case report.

Int J Surg Case Rep

July 2024

Department of Endocrinology-Diabetology-Nutrition, Mohammed VI University Hospital, Medical School, Mohamed the First University, Oujda, Morocco; Laboratory of Epidemiology, Clinical Research and Public Health, Medical School, Mohamed the First University, Oujda, Morocco. Electronic address:

Introduction And Importance: Ectopic pituitary neuroendocrine tumor (EPNET) is a very rare entity, seldom with apoplexy evolution. Only three cases of intracranial ectropic pituitary neuroendocrine tumor apoplexy were reported in the literature.

Case Presentation: We report the case of a 45-year-old woman with a history of amenorrhea, and headaches.

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Updates in the management of hypertension.

Ann Med Surg (Lond)

June 2024

Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy of Oujda, University Mohammed First.

Hypertension is the leading cause of cardiovascular diseases and nephropathies. Its treatment and management require long-term follow-up which can be facilitated by the emergence of device-based therapies. Novel recommendations have been well described in the latest ESH guidelines as well as new risk factors have been identified.

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Background: The Affordable Care Act (ACA) increased private nonemployer health insurance options, expanded Medicaid eligibility, and provided preexisting health condition protections. We evaluated insurance coverage among long-term adult survivors of childhood cancer pre- and post-ACA implementation.

Methods: Using the multicenter Childhood Cancer Survivor Study, we included participants from 2 cross-sectional surveys: pre-ACA (2007-2009; survivors: n = 7505; siblings: n = 2175) and post-ACA (2017-2019; survivors: n = 4030; siblings: n = 987).

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Previous studies support links among maternal-fetal attachment, psychological symptoms, and hormones during pregnancy and the post-partum period. Other studies connect maternal feelings and behaviors to oxytocin and suggest that an increase in oxytocin during pregnancy may prime maternal-fetal attachment. To date, researchers have not examined a possible association between maternal-fetal attachment with human placental lactogen although animal models are suggestive.

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Biliary Tract Disorders and Associated Acute Complications in Patients With Acromegaly: A Single-Center Study.

J Clin Med Res

April 2024

Department of Endocrinology-Diabetology and Nutrition, Mohammed VI University Hospital Center, Faculty of Medicine and Pharmacy, University of Mohammed First, Oujda, Morocco.

Background: Biliary complications are frequent in patients with acromegaly. These complications may be secondary either to acromegaly or to somatostatin analogs (SAs). We aimed in this paper to assess the prevalence of biliary complications in patients with acromegaly at diagnosis and after treatment with SAs.

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A psychological insight of Moroccan adults' immunisation behaviour towards emergency vaccines.

Afr J Prim Health Care Fam Med

May 2024

Laboratory of Epidemiology, Clinical Research and Public Health, Faculty of Medicine and Pharmacy, Mohammed First University, Oujda.

Background: The psychology of vaccination behaviour explains how thoughts and feelings influence people's willingness to receive vaccines. Understanding vaccination behaviour is crucial to successfully managing vaccination campaigns.

Aim: Investigating factors associated with immunisation stress among students at Mohammed First University.

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Objective: This study aims to investigate if there is an increased risk of developing tracheal stenosis after tracheostomy with an open versus percutaneous tracheostomy.

Methods: The patient cohort included patients receiving open or percutaneous tracheostomies at Catholic Health Initiatives Midwest facilities from January 2017 to June 2023. The primary aim was to compare the differences in the risk of developing tracheal stenosis between open and percutaneous tracheostomy techniques.

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ORF disease: a case report with images.

Acute Med

April 2024

Department of Dermatology, Mohammed VI University Hospital of Oujda, Medical School of Oujda, Mohammed First University of Oujda, Morocco, Department of Epidemiology, Clinical Research and Public Health Laboratory, Medical School of Oujda, Mohammed First University of Oujda, Morocco.

Article Synopsis
  • - A 25-year-old Moroccan man contracted Orf disease, a viral infection transmitted from sheep and goats to humans, after handling a sheep.
  • - He developed painful finger lesions, and doctors diagnosed him based on his exposure history and the appearance of the lesions.
  • - Treatment included antiseptics and a topical cream, leading to complete recovery within a few weeks without any lasting issues.
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Plasmapheresis in thyrotoxicosis: a single-center case series.

J Med Case Rep

March 2024

Department of Endocrinology-Diabetology and Nutrition, Faculty of Medicine and Pharmacy, Mohammed VI University Hospital Center, University of Mohammed 1st, 4806, 60049, Oujda, Morocco.

Article Synopsis
  • Plasmapheresis is explored as a therapy for hyperthyroidism, especially in severe cases like thyroid storm, where it helps quickly reduce thyroid hormone levels and antibodies.
  • The study showcases three young African patients with Graves' disease who experienced complications from traditional treatments and successfully underwent plasmapheresis, which stabilized their condition for surgery.
  • The findings suggest that while standard treatments are often effective, plasmapheresis can be a safe and efficient alternative for patients unable to tolerate conventional medications before surgery.
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Atrial fibrillation (AF) has a high economic burden on the healthcare system with rehospitalizations as the most significant contributing factor necessitating an understanding of aspects related to hospitalizations to minimize economic costs and improve patient outcomes. Our study aims to assess whether all-cause 30-day hospital readmission following AF-specific hospitalization is associated with health-related social needs (HRSN) using the Nationwide Readmissions Database (NRD). All hospitalization data were abstracted from the 2015-2019 NRD, including hospitalizations for patients at least 18 years of age with a primary discharge diagnosis of AF.

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Misdiagnosis of cutaneous epithelioid angiosarcoma as diabetic foot ulcer: a case study.

Wounds

February 2024

Department of Dermatology, Mohammed VI University Hospital of Oujda, Medical School of Oujda, Mohammed First University of Oujda, Oujda, Morocco; Department of Epidemiology, Clinical Research and Public Health Laboratory, Medical School of Oujda, Mohammed First University of Oujda, Oujda, Morocco.

Background: AS is a malignant tumor that originates from vascular endothelial cells and is known for a high rate of local recurrence and metastasis.

Case Report: A 48-year-old male presented with cutaneous epithelioid AS. Cutaneous AS of the foot is quite rare, especially in the absence of predisposing factors, and in this patient it was previously misdiagnosed as a DFU.

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Assessment of drug prescription practises in chronic hemodialysis patients: case series.

Ann Med Surg (Lond)

March 2024

Nephrology-Dialysis and Kidney Transplantation Unit, University Hospital Mohammed VI, Oujda Faculty of medicine of Oujda, Morocco Mohammed Premier University.

Introduction: The aim of the study was to assess the quality of drugs prescriptions in chronic haemodialysis patients.

Material And Methods: The authors conducted a prospective study in chronic haemodialysis patients of two haemodialysis centres in the city of Oujda eastern Morocco, during the year of 2020. The authors identified the drugs prescribed in this population with regards to the product characteristics, in terms of indications, contraindications, dosage and drug interactions.

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