3 results match your criteria: "Clinical Research and Epidemiology in Pneumonia and Sepsis (CRIPS)[Affiliation]"
Response.
Chest
April 2021
Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico Internal Medicine Department, Respiratory Unit and Cystic Fibrosis Adult Center, Milan, Italy; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. Electronic address:
A Systematic Review of the Effect of Delayed Appropriate Antibiotic Treatment on the Outcomes of Patients With Severe Bacterial Infections.
Chest
September 2020
Respiratory Unit and Cystic Fibrosis Adult Center, Internal Medicine Department, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy. Electronic address:
Background: Patients with severe bacterial infections often experience delay in receiving appropriate treatment. Consolidated evidence of the impact of delayed appropriate treatment is needed to guide treatment and improve outcomes.
Research Question: What is the impact of delayed appropriate antibacterial therapy on clinical outcomes in patients with severe bacterial infections?
Study Design And Methods: Literature searches of MEDLINE and Embase, conducted on July 24, 2018, identified studies published after 2007 reporting the impact of delayed appropriate therapy on clinical outcomes for hospitalized adult patients with bacterial infections.
Nebulization of Antiinfective Agents in Invasively Mechanically Ventilated Adults: A Systematic Review and Meta-analysis.
Anesthesiology
May 2017
From the University Health Network and Mount Sinai Hospitals, Critical Care Department, University of Toronto, Toronto, Ontario, Canada (C.S.-L.); Soins Intensifs, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland (C.S.-L.); Universitat Autonòma de Barcelona, Medicine Department, Barcelona, Spain (C.S.-L.); Multidisciplinary Intensive Care Unit, Department of Anesthesiology and Critical Care, La Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris, University Pierre et Marie Curie (UPMC) of Paris 6, Paris, France (J.-J.R.); Department of Internal Medicine, Faculty of Medicine and Health Science, Ghent University, Ghent, Belgium (S.B.); Fourth Department of Internal Medicine, Athens University School of Medicine, Attikon University General Hospital, Athens, Greece (G.P.); Service de Réanimation Médicale, Groupe Hospitalier Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Université Pierre et Marie Curie of Paris, Paris, France (J.C., C.-E.L.); Pulmonary, Critical Care and Sleep Division, Department of Medicine, State University of New York at Stony Brook, Stony Brook, New York (L.B.P.); Infectious Diseases Division, Santa Maria Misericordia University Hospital, Udine, Italy (M.B.); Emergency and Intensive Care Department, Centro Hospitalar io S. João EPE, Porto, Portugal (J.M.P.); Department of Medicine, Faculty of Medicine, University of Porto, Porto, Portugal (J.M.P.); Critical Care Department, Vall d'Hebrón University Hospital, Vall d'Hebrón Research Institute, CIBERES, Barcelona, Spain (J. Riera); Acute Intensive Care Unit, University Hospital of South Manchester, Manchester, United Kingdom (T.F.); Burns Trauma and Critical Care Research Centre, Pharmacy Department, The University of Queensland, Herston, Brisbane, Australia (J.D., J.A.R.); Department of Respiratory Medicine, German Center for Lung Research (DZL), Medizinische Hochschule, Hannover, Germany (T.W.); Nuffield Department of Primary Care Health Sciences, Oxford University, United Kingdom (J.M.G.-A.); and ESGCIP, CIBERES, Clinical Research and Epidemiology in Pneumonia and Sepsis (CRIPS), Vall d'Hebrón Institut of Research, Barcelona, Spain (J. Rello).
Background: Nebulization of antiinfective agents is a common but unstandardized practice in critically ill patients.
Methods: A systematic review of 1,435 studies was performed in adults receiving invasive mechanical ventilation. Two different administration strategies (adjunctive and substitute) were considered clinically relevant.