Almotriptan: a review of pharmacology, clinical efficacy, and tolerability.

Objective: This article summarizes preclinical and clinical data for almotriptan.

Methods: Almotriptan has been evaluated in more than 3,500 acute migraine patients in phase 2 and 3 double-blind, randomized trials and in 1,500 patients in long-term open-label trials.

Results: Controlled clinical trials show that almotriptan 12.