A Case of Toxic Epidermal Necrolysis Secondary to Acetaminophen in a Child.

Objective: To report and discuss a serious cutaneous adverse reaction in a child who was treated with acetaminophen (paracetamol).

Case Summary: A five years old male child presented a pruriginous maculopapular rash and a "drug-induced Stevens-Johnson syndrome/Toxic Epidermal Necrolysis" was suspected. Applying Spanish Pharmacovigilance System probability algorithm (modified Karch-Lasagna algorithm) for the suspected drugs (acetaminophen, ibuprofen and azithromycin), the causality of this adverse reaction was possible for acetaminophen and unlikely for the other two drugs.